Results 111 to 120 of about 104,138 (249)

Programmed Interfacial Phase Separation for Spatiotemporal Fungicide Delivery via Tunable Micro/Nano Architectures

Advanced Science, EarlyView.
ABSTRACT Translating dynamic liquid‐liquid phase separation into robust solid‐state architectures remains a challenge in materials engineering. Here, we report a composition‐driven interfacial assembly strategy that couples supramolecular coacervation with metal‐phenolic coordination to engineer tunable fungicide carriers.
Rui Zhang, Tongfang Jing, Leiming He, Kaidi Cui, Yuying Song, Xuewei Mao, Lidong Cao, Lin Zhou   +7 more
wiley   +1 more source

Characterization of Intracellular Peptides from Zebrafish (Danio rerio) Brain

, 2019
Brazilian National Research CouncilFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Brazilian National Research Council: 449390/2014-4Processo FAPESP: 2015/22752-0Processo FAPESP: 2016/04000-3Processo FAPESP: 2013/07467-0Peptides represent a ...
Correa, Claudia Neves, Manzi Teixeira, Caio Matheus [UNESP], Manzi Teixeira, Caio Matheus, Correa, Claudia Neves [UNESP], Iwai, Leo Kei, Castro, Leandro Mantovani de, Castro, Leandro Mantovani de [UNESP], Ferro, Emer Suavinho   +7 more
core   +1 more source

Thymidine exerts anti-doxorubicin-induced cardiomyopathy effect through the regulation of the PPAR signaling pathways and ferroptosis pathways

Frontiers in Pharmacology
IntroductionTo evaluate the anti-cardiomyopathic activity of thymine (Thy) and to elucidate its mechanism of action.MethodsTransgenic zebrafish with enhanced green fluorescent protein (EGFP)-labelled hearts (Tg (cmlc2: EGFP)) and wild-type AB zebrafish ...
Bin Li, Bin Li, Qifei Wang, Qifei Wang, Jiashuo Zhou, Jiashuo Zhou, Peihai Li, Peihai Li, Chen Sun, Chen Sun, Qing Xia, Qing Xia, Yun Zhang, Yun Zhang   +13 more
doaj   +1 more source

Sunscreen‐Inspired Nano‐Pesticide for UV‐Shielding and Laccase‐Responsive Delivery of Mancozeb With Enhanced Fungicidal Efficacy and Ecological Safety

Advanced Science, EarlyView.
The sunscreen‐inspired nano‐pesticide, MCB@URFSL, provides UV‐shielding, enhanced rainfastness, and laccase‐responsive delivery for improved fungicidal efficacy and high ecological safety. ABSTRACT Fungicides are a crucial tool for protecting crops and ensuring consistent food supply.
Jin Yan, Xin Ye, Linping He, Cheng Hong, Xu‐Huan Zhao, Gizachew Mulugeta Manahelohe, Xiao‐Tong Feng, Yu‐Cheng Gu, Qiang Bian, Min Wu, Ming‐Zhi Zhang   +10 more
wiley   +1 more source

Proteomics Profiling of Single Organs from Individual Adult Zebrafish

, 2010
The model organism zebrafish (Danio rerio) is extensively utilized in studies of developmental biology but is also being investigated in the context of a growing list of human age-related diseases.
Blennow, Kaj,, Brinkmalm-Westman, Ann,, Gustavsson, Mikael K,, Zetterberg, Henrik,, Pannee, Josef,, Brinkmalm, Gunnar,, von Otter, Malin,, Kettunen, Petronella,, Abramsson, Alexandra,   +8 more
core   +1 more source

Antiangiogenic Drug Testing Using Proangiogenic and Hypoxia Zebrafish Model

Bio-Protocol
Zebrafish is an excellent in vivo model for high-throughput antiangiogenic drug testing, commonly known as the zebrafish angiogenesis assay. Conventional zebrafish angiogenesis assays are performed in wild-type zebrafish to evaluate the vascular changes ...
S. Vinoth, Kirankumar Santhakumar
doaj   +1 more source

Phase Separation of TRIM21 Modulates PTPN14 Stability to Drive Flow‐Dependent Endothelial Activation and Atherogenesis

Advanced Science, EarlyView.
Disturbed flow promotes the formation of TRIM21‐rich biomolecular droplets, which concentrate TRIM21 and PTPN14 and facilitate their SPRY‐FERM interaction (illustrated by the TRIM21 D355‐PTPN14 R132 salt bridge). This condensate‐driven proximity enables TRIM21 to catalyze K48‐linked polyubiquitination of PTPN14 at lysine 956, leading to proteasome ...
Xue He, Qiannan Ma, Xue Wang, Jiaxu Mang, Chufeng Li, Bingjun Wu, Liu Yao, Yequn Chen, Qiankun Bao, Yi Zhu, Jinlong He   +10 more
wiley   +1 more source

Zebrafish Gastrulation

Annual Review of Cell and Developmental Biology
The primordial body architecture of vertebrates is established during gastrulation, a critical period of development characterized by the emergence of the three germ layers (ectoderm, mesoderm, and endoderm) and the formation of an embryo with clearly identifiable dorso-ventral and anterior-posterior axes.
openaire   +2 more sources

Carbohydrate‐Mediated Cellular Uptake of Boronic Acid Hybrids In Cellulo and Insulin‐Deficient Zebrafish: Live Imaging and Application of Multiphoton FLIM

Advanced Science, EarlyView.
Boronic acid‐based fluorescent hybrids have been used as part of a versatile platform for real‐time metabolic bioimaging across cellular and organismal scales. Including glucose‐responsive imaging in living cells and in an insulin‐deficient vertebrate model, this work opens new opportunities for the development of precision diagnostics, metabolic ...
Haobo Ge, John S. Fossey, David Gonzalez Calatayud, Stephen E. Flower, Sabrina Wang, Hanna Aitessaid, Melita Tvardauskaite, Julia Dudzic, Max Jewell, Charareh Pourzand, Stanley W. Botchway, David Gurevich, Tony D. James, Sofia I. Pascu   +13 more
wiley   +1 more source

Nephronectin regulates cardiac valve development via BMP4-HAS2 signaling in zebrafish [PDF]

, 2011
It has been estimated that about 1% of live births carry severe congenital heart defects and 20-30% among them have valve malformations. Despite its medical importance the underlying cause of many valvular diseases remains undiscovered.
Patra, Chinmoy (Dr.)
core