Results 101 to 110 of about 209,207 (313)

The hybrid history of zebrafish

G3: Genes, Genomes, Genetics
Abstract Since the description of zebrafish (Danio rerio) in 1822, the identity of its closest living relative has been unclear. To address this problem, we sequenced the exomes of 10 species in genus Danio, using the closely related Devario aequipinnatus as outgroup, to infer relationships across the 25 chromosomes of the zebrafish ...
Braedan M. McCluskey, Peter Batzel, John H. Postlethwait   +2 more
openaire   +2 more sources

Glomage: A Multimodal Platform for High‐Content Morphological and RNA Profiling of Glomeruli in Zebrafish and Mouse Models

Advanced Science, EarlyView.
Understanding how glomeruli, the kidney's filtration units, function in intact tissue remains challenging. Glomage enables rapid 3D imaging and quantitative analysis of entire glomeruli from zebrafish larvae and mice. This approach allows scalable cell quantification and detection of structural changes, advancing kidney disease research and ...
Maximilian Schindler, Tim Lange, Sophia‐Marie Bach, Soeren S. Lienkamp, Nicole Endlich   +4 more
wiley   +1 more source

The Nordic Zebrafish and Husbandry Meeting 2018

, 2019
The Nordic zebrafish and husbandry meeting took place at Karolinska Institutet in Stockholm, November 7-9, 2018. More than 120 scientists from Europe joined this meeting, which also attracted world-leading keynote speakers such as Zoltan Varga, Didier ...
Gorniok, Beata Filipek,, Braeutigam, Lars,, Aleström, Peter,, Braeutigam, L, Ledin, Johan,, Filipek-Gorniok, B, Alestrom, P, Ledin, J   +7 more
core   +1 more source

Is Emerging Nanomedicine a Friend or Foe to Germ Cells?

International Journal of Nanomedicine
Hui Yu,1,2,* Chunhui Hu,3,* Xuelin Wang,1 Ying Zhang,1 Nanhui Zhang,1 Pengxia Yu,1,2 Kai Lian,1 Jiaolong Huang,1 Peng Duan1,2 1Key Laboratory of Zebrafish Modeling and Drug Screening for Human Diseases of Xiangyang City, Xiangyang No.
Yu H, Hu C, Wang X, Zhang Y, Zhang N, Yu P, Lian K, Huang J, Duan P   +8 more
doaj  

DTX3L Inhibits the EMT, Metastasis, and Stem‐Like Features of Gastric Cancer Through Promoting GSK‐3β Dependent SNAI1 Decay

Advanced Science, EarlyView.
This research identifies DTX3L as a critical tumor suppressor that inhibits epithelial‐mesenchymal transition (EMT), invasion and metastasis in gastric cancer. By functioning as an E3 ubiquitin ligase, DTX3L targets the master EMT regulator SNAI1 for GSK‐3β‐dependent proteasomal degradation.
Yang Chen, Zhen Li, Jiajia Shen, Jingyu Lin, Xiaoli Zhao, Rui Zhang, Ying Han, Zhen Wang   +7 more
wiley   +1 more source

Proteomics Profiling of Single Organs from Individual Adult Zebrafish

, 2010
The model organism zebrafish (Danio rerio) is extensively utilized in studies of developmental biology but is also being investigated in the context of a growing list of human age-related diseases.
Blennow, Kaj,, Brinkmalm-Westman, Ann,, Gustavsson, Mikael K,, Zetterberg, Henrik,, Pannee, Josef,, Brinkmalm, Gunnar,, von Otter, Malin,, Kettunen, Petronella,, Abramsson, Alexandra,   +8 more
core   +1 more source

Reconstruction of macroglia and adult neurogenesis evolution through cross-species single-cell transcriptomic analyses

Nature Communications
Macroglia fulfill essential functions in the adult vertebrate brain, producing and maintaining neurons and regulating neuronal communication. However, we still know little about their emergence and diversification. We used the zebrafish D.
David Morizet, Isabelle Foucher, Alessandro Alunni, Laure Bally-Cuif   +3 more
doaj   +1 more source

Spontaneous Non‐Catalyzed Molecular Reactions and Interactions in the Human Body: Biomedical Implications

Advanced Science, EarlyView.
ABSTRACT The human body functions as a natural reactor for a vast network of chemical and biological reactions and physical interactions among small molecules, proteins, cells, and numerous other components. These reactions/interactions are essential for maintaining normal physiological functions.
Yuhao Cai, Chao Zhao
wiley   +1 more source

Cannabinoid Receptor 1 Regulates Zebrafish Renal Multiciliated Cell Development via cAMP Signaling

Journal of Developmental Biology
Endocannabinoid signaling plays a significant role in neurogenesis and nervous system physiology, but its roles in the development of other tissues are just beginning to be appreciated.
Thanh Khoa Nguyen, Sophia Baker, Julienne Angtuaco, Liana Arceri, Samuel Kaczor, Bram Fitzsimonds, Matthew R. Hawkins, Rebecca A. Wingert   +7 more
doaj   +1 more source

A Computational Strategy for Identifying Self‐Assembling Food‐Derived Molecules for Antiparasitic Nanotherapy

Advanced Science, EarlyView.
An integrated computational screening strategy identified ursolic acid (UA) and 18β‐glycyrrhetinic acid (18βGA) as a self‐assembling food‐derived molecular pair. The resulting carrier‐free nanoparticles (UA‐18βGA) showed synergistic antiparasitic activity, reduced combined toxicity, and host‐protective anti‐inflammatory effects in zebrafish and murine ...
Shenye Qu, Ting Wang, Jietao Liu, Jiacheng Qin, Bin Yang, Yihang Liu, Pengfei Li, Gaoxue Wang, Fei Ling   +8 more
wiley   +1 more source