Results 91 to 100 of about 104,470 (312)
Advanced Science, EarlyView.We developed a nanoparticle named OAF, which simultaneously targeted to both the brain and liver via the transferrin receptor 1 (TfR1) receptor, promoting lipoprotein receptor‐related protein 1 (LRP1) expression to enhance amyloid‐beta (Aβ) clearance. In AD mice model, OAF significantly reduced Aβ deposition and cognitive impairment, while a mitigating
Wenshuai Gong +8 more
wiley +1 more source
Advanced Science, EarlyView.Molecular, genetic, virological, and biochemical analysis in combination with global proteome and phosphoproteome profiling and functional assays were applied to study the role of PR130 in the context of HSV‐1 replication. The observations reveal that host‐intrinsic mechanisms regulate HSV‐1 replication and highlight PR130 as a susceptibility factor of
Johannes Jungwirth +10 more
wiley +1 more source
Proof of the Pudding: Applying the City-zen Methodology to Other European Cities [PDF]
, 2019 Back in 2012, a group of enthusiasts submitted a project proposal to the EU. Many talks, partner proposals, and city explorations later, City-zen was granted EU-funding “to develop and demonstrate energy efficient cities and to build a methodology and ...
Bot, Marjolein +3 more
core
Two‐Dimensional Triferroics: From Fundamental Couplings to Multifunctional Applications
Advanced Science, EarlyView.This graphic summarizes the three main types of currently reported 2D triferroic couplings. From the structural perspective, existing systems can be broadly classified into two categories, which exhibit distinct symmetry features and coupling behaviors. Beyond the lattice difference, a third type involves the interplay among ferroelectricity, magnetism,
Yang Li, Jialin Gong, Zhiqing Li
wiley +1 more source
Don't-know mind: the spirit of Korean zen
, 2004 An excerpt from Zen Master Wu Kwang's new book "Don't-know mind: the spirit of Korean ...
Wu Kwang, Zen Master (Shrobe, Richard)
core
Advanced Science, EarlyView.We report the development of biotinylated PEGylated bilirubin‐coated perfluoropentane (bt‐PEG‐BR@PFP) nanobubbles, a novel class of ROS‐activatable and dual‐modality contrast agents that amplify both ultrasound (US) and magnetic resonance imaging (MRI) signals in response to elevated ROS.
Wonsik Jung +6 more
wiley +1 more source
Mu Shim Sunim gets a Zen Stick
, 1997 On February 23, 1997, Ven. Mu Shim Sunim received inka from Zen Master Seung Sahn at the Seoul International Zen Center, Hwa Gye Sah Temple, in Seoul.
Dae Jin Mu Shim Sunim, Zen Master
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Advanced Science, EarlyView.This study identifies a FOSL2‐driven positive feedback loop that amplifies FSH/FSHR signaling. During FSH‐dependent follicle maturation, FSH induces Fosl2 expression via the cAMP‐PKA‐CREB cascade. FOSL2 in turn binds the promoters of Fshr and estrogen‐biosynthesis genes to enhance their transcription, thereby increasing Fshr mRNA level and amplifying ...
Hongru Shi +13 more
wiley +1 more source
Frontiers in MicrobiologyZearalenone (ZEN), a naturally occurring estrogenic mycotoxin prevalent in cereals and animal feed, poses significant challenge to livestock industry owing to its detrimental effects on animal reproduction.
Jiagao Chang +6 more
doaj +1 more source