The origin and diversification of Amaryllidaceae: A phylogenetic and biogeographic analysis [PDF]
Abstract Premise Previous angiosperm‐wide studies estimated that the geophytic family Amaryllidaceae diverged in Africa 87.00–46.77 million years ago (mya), spanning the Cretaceous and Palaeogene periods, including multiple important climatic and geological events.
Zoë H. Dennehy‐Carr +4 more
wiley +2 more sources
Tissue-Specific Natural Synthesis of Galanthaminein Zephyranthes Species and Its Accumulation in Different In Vitro-Grown Organs Following Methyl Jasmonate Treatment [PDF]
Galanthamine is an immensely valuable alkaloid exhibiting anti-cancer and antiviral activity. The cultivation of plant tissues in in vitro conditions is a good source for the synthesis and enrichment of secondary metabolites of commercial interest.
Rukaya Syeed +9 more
doaj +2 more sources
ERK Inhibition Promotes Engraftment of Allografts by Reprogramming T‐Cell Metabolism [PDF]
Extracellular regulated protein kinases (ERK) pathway is highly activated in graft‐infiltrating T cells. Lycorine, an amaryllidaceae alkaloid extracted from the traditional Chinese medicine Zephyranthes candida, presents to be a novel ERK‐specific inhibitor and prolongs engraftment of allografts.
Xiaosheng Tan +15 more
wiley +2 more sources
Elucidating the enzyme network driving Amaryllidaceae alkaloids biosynthesis in Leucojum aestivum [PDF]
Schematic representation of Amaryllidaceae alkaloid biosynthesis in Leucojum aestivum. Norbelladine synthase (LaNBS) and noroxomaritidine/norcraugsodine reductase (LaNRII) catalyze the condensation of tyramine and 3,4‐dihydroxybenzaldehyde to form norbelladine, which is subsequently O‐methylated by norbelladine‐4′‐O‐methyltransferase (LaN4′OMT ...
Basanta Lamichhane +6 more
wiley +2 more sources
Flavonoids and alkaloids from the rhizomes of Zephyranthes ajax Hort. and their cytotoxicity [PDF]
A new flavanol derivative, (2R,3R)-3-acetoxy-7-hydroxy-3′,4′-methylenedioxyflavan (1), was co-isolated from the rhizomes of Zephyranthes ajax Hort. with the following seven known compounds: 7-hydroxyflavan (2), 7,4′-dihydroxyflavan (3), 7,4′-dihydroxy-8 ...
Khan Viet Nguyen +6 more
doaj +2 more sources
Anticoronavirus Isoquinoline Alkaloids: Unraveling the Secrets of Their Structure–Activity Relationship [PDF]
ABSTRACT Background Natural alkaloids are a structurally diverse class of bioactive compounds with significant therapeutic potential. This study aimed to evaluate the in vitro antiviral activity of various natural alkaloids against coronaviruses, clarify molecular effects via bioassays and docking, and explore structure–activity relationships.
Marcela Safratova +11 more
wiley +2 more sources
Undescribed Amaryllidaceae Alkaloids from Zephyranthes citrina and Their Cytotoxicity [PDF]
This phytochemical study presents the isolation of eight alkaloids from Zephyranthes citrina Baker. The structures of the new alkaloids, zephycitrine (1) and 6-oxonarcissidine (2), were established by analysis of spectroscopic and spectrometric data. Processing the EtOH extract under acid-base conditions yielded the unreported isolation artifacts 3 and
Křoustková, Jana +11 more
openaire +3 more sources
The demand for green synthesis of metal oxide nanomaterials is increasing tremendously to achieve sustainable development goals and for a clean environment. Simultaneously, metal oxides hold significant importance across various fields, such as catalysis,
Sanjana Afrin Disha +3 more
doaj +2 more sources
Influence of Sucrose and Activated Charcoal on Phytochemistry and Vegetative Growth in Zephyranthes irwiniana (Ravenna) Nic. García (Amaryllidaceae) [PDF]
Zephyranthes irwiniana (Ravenna) Nic. García is an endemic, red list threatened species from the Brazilian savanna (Cerrado) with pharmacological potential to treat the symptoms of Alzheimer’s Disease (AD).
Bertholdo Dewes Neto +6 more
doaj +2 more sources
Alkaloids are a type of natural compound possessing different pharmacological activities. Natural products, including alkaloids, which originate from plants, have emerged as potential protective agents against neurodegenerative disorders (NDDs) and chronic inflammations. A wide array of prescription drugs are used against these conditions, however, not
Babita Aryal +13 more
wiley +1 more source

