Results 11 to 20 of about 2,614 (204)

Endocrine-disrupting compounds and metabolomic reprogramming in breast cancer. [PDF]

open access: yesJ Biochem Mol Toxicol, 2023
Abstract Endocrine‐disrupting chemicals pose a growing threat to human health through their increasing presence in the environment and their potential interactions with the mammalian endocrine systems. Due to their structural similarity to hormones like estrogen, these chemicals can interfere with endocrine signaling, leading to many deleterious ...
Winz C, Zong WX, Suh N.
europepmc   +2 more sources

Annual banned‐substance review—Analytical approaches in human sports drug testing 2021/2022–

open access: yesDrug Testing and Analysis, Volume 15, Issue 1, Page 5-26, January 2023., 2023
Detection assays for drugs and methods of sports doping published between 2021 and 2022 are critically reviewed and evaluated in context with the Prohibited List 2022 as established by the World Anti‐Doping Agency. Abstract Also in 2021/2022, considerable efforts were invested into advancing human sports drug testing programs, recognizing and taking ...
Mario Thevis, Tiia Kuuranne, Hans Geyer
wiley   +1 more source

Determination and enantioselective separation of zilpaterol in human urine after mimicking consumption of contaminated meat using high‐performance liquid chromatography with tandem mass spectrometry techniques

open access: yesRapid Communications in Mass Spectrometry, Volume 36, Issue 19, 15 October 2022., 2022
Rationale The synthetic β‐adrenoreceptor agonist zilpaterol is legitimately used as an animal feed supplement in selected countries due to its known effects on lipolysis and protein biosynthesis. These pharmacological characteristics of zilpaterol have contributed to its classification as doping agent in sport by the World Anti‐Doping Agency.
Luisa Euler   +3 more
wiley   +1 more source

Post‐mortem investigation into a death involving doping agents: The case of a body builder

open access: yesDrug Testing and Analysis, Volume 14, Issue 10, Page 1795-1799, October 2022., 2022
Abstract Introduction A young male was found dead on the bed of a hotel room. He was expected to take part in a bodybuilding competition the day after. During the site inspection, drugs of different types were found. The next day, an autopsy was performed. The evidence of cardiomegaly with organ congestion involving lung, liver, kidneys, adrenal glands,
Donata Favretto   +5 more
wiley   +1 more source

Drug disposition in cholestasis: An important concern. [PDF]

open access: yesPharmacol Res Perspect
Abstract Cholestasis, a chronic liver condition, disrupts bile acid homeostasis and complicates drug disposition, posing significant challenges in medicating cholestatic patients. Drug metabolism enzymes and transporters (DMETs) are pivotal in drug clearance.
Shang T, Zhang C, Liu D.
europepmc   +2 more sources

Annual banned‐substance review: Analytical approaches in human sports drug testing 2020/2021

open access: yesDrug Testing and Analysis, Volume 14, Issue 1, Page 7-30, January 2022., 2022
Detection assays for drugs and methods of sports doping published between 2020 and 2021 are critically reviewed and evaluated in context with the Prohibited List 2021 as established by the World Anti‐Doping Agency. Abstract Most core areas of anti‐doping research exploit and rely on analytical chemistry, applied to studies aiming at further improving ...
Mario Thevis, Tiia Kuuranne, Hans Geyer
wiley   +1 more source

Sports drug testing and the athletes' exposome

open access: yesDrug Testing and Analysis, Volume 13, Issue 11-12, Page 1814-1821, November-December 2021., 2021
Investigations into the athlete's exposome and how to distinguish between deliberate drug use and different contamination scenarios has become a central topic of antidoping research, and a variety of challenges need to be taken into consideration. Abstract Similar to the general population, elite athletes are exposed to a complex set of environmental ...
Mario Thevis   +3 more
wiley   +1 more source

Características de carcaça de bezerros de rebanhos leiteiros desmamados precocemente e alimentados com diferentes dietas líquidas Effect of feeding different liquid diets on carcass characteristics of early weaned dairy calves

open access: yesRevista Brasileira de Zootecnia, 2005
Avaliaram-se o rendimento de carcaça e o desenvolvimento dos órgãos e vísceras de 40 bezerros mestiços F1 Holandês x Gir alimentados com diferentes dietas líquidas, à base de leite integral ou colostro fermentado, associados ou não com óleo de soja (45 ...
Antonio Bento Mancio   +4 more
doaj   +1 more source

Nanoporous gold: A review and potentials in biotechnological and biomedical applications

open access: yesNano Select, Volume 2, Issue 8, Page 1437-1458, August 2021., 2021
In summary, this review not only briefly introduces the preparation, characterization, and modification of NPG, but also comprehensively analyzes the representative research results of NPG in the fields of biotechnology and biomedicine: catalysis, biosensors, biofuel cells, and drug delivery. In addition, the main challenges and future opportunities of
Sa Xiao   +3 more
wiley   +1 more source

Annual banned‐substance review: Analytical approaches in human sports drug testing 2019/2020

open access: yesDrug Testing and Analysis, Volume 13, Issue 1, Page 8-35, January 2021., 2021
Detection assays for drugs and methods of sports doping published between 2019 and 2020 are critically reviewed and evaluated in context with the Prohibited List 2020 as established by the World Anti‐Doping Agency. Abstract Analytical chemistry‐based research in sports drug testing has been a dynamic endeavor for several decades, with technology‐driven
Mario Thevis, Tiia Kuuranne, Hans Geyer
wiley   +1 more source

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