Results 51 to 60 of about 192,785 (264)
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2016 This paper uses an estimated DSGE model of the Czech economy to study the macroeconomic implications of various shocks when the interest rate is constrained by the zero lower bound.
Miroslav Hloušek
doaj +1 more source
On closed-form tight bounds and approximations for the median of a gamma distribution.
PLoS ONE, 2021 The median of a gamma distribution, as a function of its shape parameter k, has no known representation in terms of elementary functions. In this work we use numerical simulations and asymptotic analyses to bound the median, finding bounds of the form 2 ...
Richard F Lyon
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Hair distributions in noncommutative Einstein-Born-Infeld black holes
Nuclear Physics B, 2019 We study hair mass distributions in noncommutative Einstein-Born-Infeld hairy black holes with non-zero cosmological constants. We find that the larger noncommutative parameter makes the hair easier to condense in the near horizon area. We also show that
Yan Peng
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
PRICE-LEVEL TARGETING – A VIABLE ALTERNATIVE TO INFLATION TARGETING? [PDF]
CES Working Papers, 2012 The recent financial crisis that has led some central banks reaching the zero lower bound of their interest rate to use unconventional monetary policy instruments, has brought to the forefront theacademic discussions on the shift from inflation targeting
Iulian Vasile Popescu
doaj
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Bounds for the Zero Forcing Number of Graphs with Large Girth
Theory and Applications of Graphs, 2015 The zero-forcing number, Z(G) is an upper bound for the maximum nullity of all symmetric matrices with a sparsity pattern described by the graph. A simple lower bound is δ ≤ Z(G) where δ is the minimum degree.
Randy Davila, Franklin Kenter
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Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source