Results 61 to 70 of about 196,831 (306)
Bounds for the Zero Forcing Number of Graphs with Large Girth
Theory and Applications of Graphs, 2015 The zero-forcing number, Z(G) is an upper bound for the maximum nullity of all symmetric matrices with a sparsity pattern described by the graph. A simple lower bound is δ ≤ Z(G) where δ is the minimum degree.
Randy Davila, Franklin Kenter
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Discretionary monetary policy and the zero lower bound on nominal interest rates [PDF]
, 2005 Ignoring the existence of the zero lower bound on nominal interest rates one considerably understates the value of monetary commitment in New Keynesian models. A stochastic forward-looking model with lower bound, calibrated to the U.S.
Billi, Roberto +2 more
core
The decay rates of solutions to a chemotaxis-shallow water system
Electronic Journal of Qualitative Theory of Differential Equations, 2021 In this paper, we consider the large time behavior of solution for the chemotaxis-shallow water system in $\mathbb{R}^2$. The lower bound for time decay rates of the bacterial density and the chemoattractant concentration are proved by the method of ...
Yanqiu Huang, Qiang Tao
doaj +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
PRICE-LEVEL TARGETING – A VIABLE ALTERNATIVE TO INFLATION TARGETING? [PDF]
CES Working Papers, 2012 The recent financial crisis that has led some central banks reaching the zero lower bound of their interest rate to use unconventional monetary policy instruments, has brought to the forefront theacademic discussions on the shift from inflation targeting
Iulian Vasile Popescu
doaj
On the Empirical (Ir)Relevance of the Zero Lower Bound Constraint [PDF]
NBER Macroeconomics Annual, 2019 The magnitude of the global financial crisis of 2007–8 and the recession that it triggered ledmany central banks to lower their policy rates down to values near zero, their theoretical lower bound.1 In the United States, the target for the federal funds rate remained at zero for 7 years, from January 2009 through December 2015.
Debortoli, Davide +2 more
openaire +3 more sources
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Public Investment, Time to Build, and the Zero Lower Bound [PDF]
SSRN Electronic Journal, 2014 Abstract We study the effectiveness of public investment in stimulating an economy stuck in a liquidity trap. We do so in the context of a tractable new-Keynesian economy in which a fraction of government spending increases the stock of public capital subject to a time-to-build constraint.
Bouakez, Hafedh +2 more
openaire +5 more sources
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source