Results 71 to 80 of about 1,474,906 (296)

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

open access: yesFEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Sign changes of Fourier coefficients of Siegel cusp forms of degree two on Hecke congruence subgroups

open access: yes, 2017
In this article, the authors give a lower bound on the number of sign changes of Fourier coefficients of a non-zero degree two Siegel cusp form of even integral weight on a Hecke congruence subgroup.
Gun, S., Sengupta, J.
core   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Transport coefficients in non-quasiparticle systems

open access: yesEPJ Web of Conferences, 2011
Transport coefficients, in particular the shear viscosity to entropy density ratio are studied in systems where the small-width quasiparticle assumption is not valid.
Jakovác A.
doaj   +1 more source

Projection to Mixture Families and Rate-Distortion Bounds with Power Distortion Measures

open access: yesEntropy, 2017
The explicit form of the rate-distortion function has rarely been obtained, except for few cases where the Shannon lower bound coincides with the rate-distortion function for the entire range of the positive rate. From an information geometrical point of
Kazuho Watanabe
doaj   +1 more source

Prognostic Impact of European LeukemiaNet Genetic Risk Stratification System in Adult Patients With Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha   +4 more
wiley   +1 more source

Note on quantum discord

open access: yesResults in Physics
Quantum discord goes beyond entanglement and exists in a wide range of quantum states that may be separable, playing a crucial role in quantum information tasks.
Yiding Wang   +2 more
doaj   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

Optimal Monetary Policy under Commitment with a Zero Bound on Nominal Interest Rates [PDF]

open access: yes
We determine optimal monetary policy under commitment in a forwardlooking New Keynesian model when nominal interest rates are bounded below by zero. The lower bound represents an occasionally binding constraint that causes the model and optimal policy to
Klaus Adam, Roberto M. Billi
core   +3 more sources

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu   +10 more
wiley   +1 more source

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