Results 101 to 110 of about 2,775,940 (306)

Threonine 348 regulates the subcellular localization of PTEN

open access: yesFEBS Open Bio, EarlyView.
Thr348 in the C2 domain is a key contributor to PTEN subcellular localization. The PTEN350 fragment and PTENA4 accumulated in the nucleus, whereas PTENK13R,A4 predominantly localized to the plasma membrane. In contrast, substitution of Thr348 with Asp (T348D) disrupted these characteristic localization patterns, resulting in predominant cytoplasmic ...
Takashi Kato, Suzu Tanaka, Miyu Ohashi
wiley   +1 more source

Subsequence sums of a zero-sumfree sequence

open access: yesEuropean Journal of Combinatorics, 2009
Let \(G\) be a finite additive Abelian group and let \(S=\{a_i\}_{i=1}^n\) be a finite sequence of elements of \(G\). Define \[ \Sigma(S)=\left\{\sum_{i\in I}a_i:\emptyset\neq I\subseteq\{1,\dots,n\}\right\}. \] The author shows the inequality \(|\Sigma(S)|\geq 2n-1\) provided that \(0\not\in\Sigma(S)\) and the group generated by \(a_1,\dots,a_n\) is ...
openaire   +1 more source

Polynomials with real zeros and Pólya frequency sequences

open access: yesJournal of Combinatorial Theory, Series A, 2005
12 ...
Yi Wang 0027, Yeong-Nan Yeh
openaire   +2 more sources

Using fluorescence fluctuation spectroscopy to quantify molecular dynamics within cells

open access: yesFEBS Open Bio, EarlyView.
Microscopy techniques like fluorescence correlation spectroscopy (FCS) and number and brightness analysis (N&B) allow to quantify concentrations, diffusion rates, and oligomerization of fluorescently labeled molecules in the living cell. In this protocol the principles of how to set up these types of experiments are described including calibration ...
Mark A. Hink
wiley   +1 more source

Zero-sum balanced binary sequences

open access: yes, 2012
For every positive integer n ≡ 0 mod 4, we construct a zero-sum {±1}-sequence of length n which is balanced, i.e., whose associated Steinhaus triangle contains as many +1’s as −1’s. This implies the existence of balanced binary sequences of every length m ≡ 0 or 3 mod 4, thereby providing a new solution to a problem posed by Steinhaus in 1963.
Eliahou, Shalom   +2 more
openaire   +4 more sources

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source

Iterated sequences and the geometry of zeros [PDF]

open access: yesJournal für die reine und angewandte Mathematik (Crelles Journal), 2011
15 pages. To appear in J. Reine Angew. Math. (Crelle's journal)
openaire   +3 more sources

Zero-shot Information Retrieval

open access: yes, 2023
With advancements in Transformer models, Zero-shot Information Retrieval (IR) has seen remarkable progress. Document retrieval saves time for knowledge workers seeking relevant documents from a corpus.
JIANG OU (17284639)
core   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu   +21 more
wiley   +1 more source

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