Results 81 to 90 of about 2,048,363 (280)

Polynomials with Real Zeros and Compatible Sequences

open access: yesThe Electronic Journal of Combinatorics, 2012
In this paper, we study polynomials with only real zeros based on the method of compatible zeros. We obtain a necessary and sufficient condition for the compatible property of two polynomials whose leading coefficients have opposite sign. As applications, we partially answer a question proposed by M. Chudnovsky and P. Seymour in the recent publication [
openaire   +2 more sources

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

open access: yesFEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Research on single-phase grounding characteristics of low-resistance grounding systems with distributed generation

open access: yesInternational Journal of Electrical Power & Energy Systems
The network-level characteristics of zero-sequence currents during single-phase ground faults in existing low-resistance grounding systems with inverter-interfaced distributed generators (IIDGs) remain unclear. Moreover, the influence of IIDG integration
Jianwen Zhao, Fuyang Zeng
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Long $n$-zero-free sequences in finite cyclic groups

open access: yes, 2006
A sequence in the additive group ${\mathbb Z}_n$ of integers modulo $n$ is called $n$-zero-free if it does not contain subsequences with length $n$ and sum zero.
Chen, Fang, Savchev, Svetoslav
core   +2 more sources

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

Development of a Prediction Model for Progression Risk in High‐Grade Gliomas Based on Habitat Radiomics and Pathomics

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate the value of constructing models based on habitat radiomics and pathomics for predicting the risk of progression in high‐grade gliomas. Methods This study conducted a retrospective analysis of preoperative magnetic resonance (MR) images and pathological sections from 72 patients diagnosed with high‐grade gliomas (52 ...
Yuchen Zhu   +14 more
wiley   +1 more source

On Subsequence Sums of a Zero-sum Free Sequence [PDF]

open access: yesThe Electronic Journal of Combinatorics, 2007
Let $G$ be a finite abelian group with exponent $m$, and let $S$ be a sequence of elements in $G$. Let $f(S)$ denote the number of elements in $G$ which can be expressed as the sum over a nonempty subsequence of $S$. In this paper, we show that, if $|S|=m$ and $S$ contains no nonempty subsequence with zero sum, then $f(S)\geq 2m-1$.
openaire   +2 more sources

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