Results 61 to 70 of about 812,870 (286)

Prognostic Impact of European LeukemiaNet Genetic Risk Stratification System in Adult Patients With Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha, Bishwas Mandal, Vishal Mandal, Asis Shrestha, Amir Babu Shrestha   +4 more
wiley   +1 more source

Using the Zero Trust Five-Step Implementation Process with Smart Environments: State-of-the-Art Review and Future Directions

Future Internet
There is a growing pressure on industry to secure environments and demonstrate their commitment in taking right steps to secure their products. This is because of the growing number of security compromises in the IT industry, Operational Technology ...
Shruti Kulkarni, Alexios Mylonas, Stilianos Vidalis   +2 more
doaj   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Securing the Metaverse: A Blockchain-Enabled Zero-Trust Architecture for Virtual Environments

IEEE Access
In order to improve cybersecurity in newly developed network infrastructures, this research investigates the integration of blockchain technology with zero-trust security concepts. The zero-trust paradigm ensures continuous authentication across entities,
Ikram Ud Din, Kamran Habib Khan, Ahmad Almogren, Mahdi Zareei, Jesus Arturo Perez Diaz   +4 more
doaj   +1 more source

Toward Zero-Trust Security for the Metaverse

IEEE Communications Magazine
By focusing on immersive interaction among users, the burgeoning Metaverse can be viewed as a natural extension of existing social media. Similar to traditional online social networks, there are numerous security and privacy issues in the Metaverse (e.g., attacks on user authentication and impersonation).
Ruizhi Cheng, Songqing Chen, Bo Han 0001
openaire   +2 more sources

Evaluating the impact of an enhanced energy performance standard on load-bearing masonry domestic construction: Understanding the gap between designed and real performance: lessons from Stamford Brook. [PDF]

, 2011
This report is aimed at those with interests in the procurement, design and construction of new dwellings both now and in the coming years as the Government’s increasingly stringent targets for low and zero carbon housing approach. It conveys the results
Bell, M, Lowe, RJ, Miles-Shenton, D, South, T, Wingfield, J   +4 more
core  

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Development of a Prediction Model for Progression Risk in High‐Grade Gliomas Based on Habitat Radiomics and Pathomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate the value of constructing models based on habitat radiomics and pathomics for predicting the risk of progression in high‐grade gliomas. Methods This study conducted a retrospective analysis of preoperative magnetic resonance (MR) images and pathological sections from 72 patients diagnosed with high‐grade gliomas (52 ...
Yuchen Zhu, Yuxi Gong, Weilin Xu, Xingjian Sun, Gefei Jiang, Lei Qiu, Kexin Shi, Mengxing Wu, Yinjiao Fei, Jinling Yuan, Jinyan Luo, Yurong Li, Yuandong Cao, Minhong Pan, Shu Zhou   +14 more
wiley   +1 more source

A descriptive analysis of general acute Trust star ratings [PDF]

This paper examines the relationship between acute NHS Trust star ratings in England (generated by the Department of Health) in 2000/01 and 2001/02 with various other Trust characteristics and performance indicators from a Trust level database maintained
Peter Smith, Rowena Jacobs
core