Results 191 to 200 of about 516,911 (342)

Regulating Tumor Metabolic Reprogramming with Biomimetic Co‐Delivery of Simvastatin and Kynureninase for Immunotherapy

Advanced Science, EarlyView.
After the intravenous injection of biomimetic and pH/ROS‐responsive PTSK@CRM, the nanoparticles can be accumulated in tumors and release Sim and KYNase to inhibit the tumor growth, regulate the metabolism of cholesterol and Kyn, and reverse the immunosuppressive tumor microenvironment.
Jiaxin Yin, Shengcai Yang, Zengguang Liu, Songchen Zhao, Siyu Sun, Ziling Liu, Quanshun Li   +6 more
wiley   +1 more source

Measurements, Predictions, and Control in Microgrids and Power Electronic Systems. [PDF]

Sensors (Basel), 2023
Baier CR, Hernández JC, Wheeler P.
europepmc   +1 more source

Gallium‐Doped MXene Nanozymes Protect Liver Through Multi‐Death Pathway Blockade and Hepatocyte Regeneration

Advanced Science, EarlyView.
This study develops gallium‐doped V2C MXene nanozymes (Ga‐V2C) to treat acetaminophen‐induced liver injury through multi‐death pathway blockade and hepatocyte regeneration. Unlike conventional single‐target therapies like N‐acetylcysteine, Ga‐V2C nanozymes enable oxidative stress suppression, apoptosis, and ferroptosis inhibition, and enhanced ...
Xiaopeng Cai, Jingwen Deng, Liqing Wang, Junjie Su, Dongyi Xian, Yilang Yan, Xinyu Yang, Chuanbin Wu, Tingting Peng, Yuan Ding, Guilan Quan, Weilin Wang, Min Zhou, Chao Lu   +13 more
wiley   +1 more source

Optimizing switching sequences in AC-AC converters for enhanced safety and performance in conveyor systems. [PDF]

Sci Rep
Dhandapani V, Balasubramanian G.
europepmc   +1 more source

Beyond Catalytic Therapy: Copper‐Paeonol Nanozymes Disrupt Fascin‐Mediated Actin Bundling to Suppress Tumor Growth and Metastasis

Advanced Science, EarlyView.
Copper‐paeonol nanozymes target tumor‐specific reactive oxygen species generation and disrupt fascin‐mediated actin bundling, effectively suppressing tumor growth and metastatic colonization. Abstract Fascin, an actin‐bundling protein universally upregulated in metastatic tumors, drives tumor migration and invasion by promoting filopodia and ...
Peiying Zhang, Huajun Li, Yisen Wang, Jie Xiang, Lei Fan, Shengzhe Zhang, Lizeng Gao, Hua Dai, Juqun Xi   +8 more
wiley   +1 more source

A versatile immunomodulated nanoCRISPR converter augments the susceptibility and visibility of tumors to the immune system. [PDF]

Proc Natl Acad Sci U S A
Li Y, Zhou S, Fu W, Li X, Chen T, Le H, Xu Y, Tang Y, Mi P, Gao H, Wu Q, Gong C.   +11 more
europepmc   +1 more source

Simplified Nonlinear Current-Mode Control of DC-DC Cuk Converter for Low-Cost Industrial Applications. [PDF]

Sensors (Basel), 2023
Al-Baidhani H, Kazimierczuk MK.
europepmc   +1 more source

Construction of PANoptosis‐Inhibiting Carbonized Polymer Dots via Machine Learning Potential for Mitigating Chemodrug‐Induced Nephrotoxicity

Advanced Science, EarlyView.
An enhanced sampling method is developed for molecular dynamics based on trained machine learning force fields to guide the construction of PANoptosis‐inhibiting carbonized polymer dots (Lu‐CDs) derived from a flavonoid compound for treating chemodrug‐induced nephrotoxicity.
Xinchen Liu, Jiaxin Zhang, Xiangyu Yan, Nuo Li, Yu‐Chao Dong, Zihao Wang, Daowei Li, Yong Du, Huan Wang   +8 more
wiley   +1 more source

Computed tomography image analysis of cobalt oxide nanoparticles-induced cytopathic effect on Hep-G2 cell lines. [PDF]

RSC Adv
Nasr Eldin MS, Soula MA, Emara AA, Ahmed HM, Al-Bishri WM, El-Sayyad GS.   +5 more
europepmc   +1 more source

Energy Channeling Led Driver Technology to achieve Flicker Free Operation with Zeta Converter for Power Quality Improvement [PDF]

, 2020
K.B. Bhaskar, Paramasivam Alagumariappan, Mohamed Shuaib Mohamed Saheed   +2 more
openalex   +1 more source