Results 161 to 170 of about 25,606 (215)
Recent Nanotherapeutic Advancements Against HIV-Associated Neurocognitive Disorders (HAND). [PDF]
BiomoleculesTrivedi R, Gothwal A, Layek B, Singh J.
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Characterizing multimorbidity and the risk for hospitalization among people living with HIV from the African Cohort Study. [PDF]
BMC Glob Public HealthScott R +12 more
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Kidney Dysfunction In Young People Living With HIV On Dolutegravir-Based Regimens In Kampala, Uganda
Nasuuna EM +4 more
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General Pharmacology: The Vascular System, 1995
1. The anti-HIV drug zidovudine (3'-azido-2',3'-dideoxythymidine; ZDV) has three important pathways of metabolism. ZDV is a prodrug and must be phosphorylated in lymphocytes in order to exert its antiviral action. However, in quantitative terms this is a minor pathway probably accounting for less than 1% of the overall metabolic profile.
G J, Veal, D J, Back
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1. The anti-HIV drug zidovudine (3'-azido-2',3'-dideoxythymidine; ZDV) has three important pathways of metabolism. ZDV is a prodrug and must be phosphorylated in lymphocytes in order to exert its antiviral action. However, in quantitative terms this is a minor pathway probably accounting for less than 1% of the overall metabolic profile.
G J, Veal, D J, Back
openaire +2 more sources
Journal of Pharmaceutical Sciences, 2009 Bidirectional transport studies were conducted using Caco-2, MDCK, and MDCK-MDR1 to determine P-gp influences in lamivudine and zidovudine permeability and evaluate if zidovudine permeability changes with the increase of zidovudine concentration and/or ...
Jacqueline De Souza +2 more
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Nursing Standard, 1989
AIDS dementia complex may be prevented by treatment with antiviral agents.
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AIDS dementia complex may be prevented by treatment with antiviral agents.
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Clinical Infectious Diseases, 1990
Patients may be intolerant of zidovudine for several reasons, the most prominent being hematologic toxicity. In vitro studies demonstrate that zidovudine is toxic to the myeloid and erythroid precursors in the bone marrow; at concentrations of zidovudine near those associated with the optimal antiviral effect in vitro, the proliferative capability of ...
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Patients may be intolerant of zidovudine for several reasons, the most prominent being hematologic toxicity. In vitro studies demonstrate that zidovudine is toxic to the myeloid and erythroid precursors in the bone marrow; at concentrations of zidovudine near those associated with the optimal antiviral effect in vitro, the proliferative capability of ...
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International Journal of Dermatology, 1989
La zidovudine est actuellement le seul medicament disponible pour le traitement des infections par HIV et ses indications sont encore mal connues. Etant donne la toxicite de la zidovudine constatee lors de differentes etudes, notamment la toxicite medullaire et hematologique et le cout eleve du traitement, il n'y a aucune indication a utiliser cette ...
openaire +2 more sources
La zidovudine est actuellement le seul medicament disponible pour le traitement des infections par HIV et ses indications sont encore mal connues. Etant donne la toxicite de la zidovudine constatee lors de differentes etudes, notamment la toxicite medullaire et hematologique et le cout eleve du traitement, il n'y a aucune indication a utiliser cette ...
openaire +2 more sources