Results 1 to 10 of about 20,764 (191)

Nevirapine Increases Sodium/Iodide Symporter-Mediated Radioiodide Uptake by Activation of TSHR/cAMP/CREB/PAX8 Signaling Pathway in Dedifferentiated Thyroid Cancer

Frontiers in Oncology, 2020
Nevirapine has been proved to be effective in inducing re-differentiation and suppressing tumor growth in several tumor cells. This study aims to investigate the therapeutic potential of nevirapine in dedifferentiated thyroid cancer (DeTC), which ...
Hongxia Shang, Junyu Zhao, Junyu Zhao, Jinming Yao, Huanjun Wang, Jianjun Dong, Lin Liao, Lin Liao   +7 more
doaj   +1 more source

Prevention of Parent to Child Transmission of HIV: Single Centre Experience of 14 years at Tertiary Care Hospital in Delhi, India [PDF]

Journal of Clinical and Diagnostic Research, 2017
Introduction: Prevention of Parent To Child Transmission (PPTCT) of HIV/AIDS is an integral component of AIDS control programme. PPTCT is an ongoing programme since last 15 years.
AG Radhika, Sonia Chawla, Sruthi Bhaskaran   +2 more
doaj   +1 more source

Review The Emerging Profile of Cross-Resistance among the Nonnucleoside HIV-1 Reverse Transcriptase Inhibitors

Viruses, 2014
Nonnucleoside reverse transcriptase inhibitors (NNRTIs) are widely used to treat HIV-1-infected individuals; indeed most first-line antiretroviral therapies typically include one NNRTI in combination with two nucleoside analogs.
Nicolas Sluis-Cremer
doaj   +1 more source

Dipyridodiazepinone derivatives; synthesis and anti HIV-1 activity

Beilstein Journal of Organic Chemistry, 2009
Ten dipyridodiazepinone derivatives were synthesized and evaluated for their anti HIV-1 reverse transcriptase activity against wild-type and mutant type enzymes, K103N and Y181C. Two of them were found to be promising inhibitors for HIV-1 RT.
Nisachon Khunnawutmanotham, Nitirat Chimnoi, Arunee Thitithanyanont, Patchreenart Saparpakorn, Kiattawee Choowongkomon, Pornpan Pungpo, Supa Hannongbua, Supanna Techasakul   +7 more
doaj   +1 more source

The antiretroviral efficacy of highly active antiretroviral therapy and plasma nevirapine concentrations in HIV-TB co-infected Indian patients receiving rifampicin based antituberculosis treatment

AIDS Research and Therapy, 2011
Background Rifampicin reduces the plasma concentrations of nevirapine in human immunodeficiency virus (HIV) and tuberculosis (TB) co-infected patients, who are administered these drugs concomitantly.
Sinha Sanjeev, Dhooria Sahajal, Kumar Sanjiv, Shah Nipam, Velpandian T, Ravi AK, Kumar Narendra, Ahmad Hafeez, Bhargwa Akshat, Chug Karan, Bumma Naresh, Chandrashekhar Rahul, Ekka Meera, Sreenivas Vishnu, Sharma Surendra K, Samantaray JC, Mitsuyasu Ronald   +16 more
doaj   +1 more source

Investigating the continuous synthesis of a nicotinonitrile precursor to nevirapine

Beilstein Journal of Organic Chemistry, 2013
2-Chloro-3-amino-4-picoline (CAPIC) is a strategic building block for the preparation of nevirapine, a widely-prescribed non-nucleosidic reverse transcriptase inhibitor for the treatment of HIV-infected patients.
Ashley R. Longstreet, Suzanne M. Opalka, Brian S. Campbell, B. Frank Gupton, D. Tyler McQuade   +4 more
doaj   +1 more source

Green HPLC quantification method of lamivudine, zidovudine and nevirapine with identification of related substances in tablets

Green Chemistry Letters and Reviews, 2022
A green HPLC method for lamivudine (3TC), zidovudine (AZT) and nevirapine (NVP) determination in fixed-dose combination tablets was developed using ethanol as both one of the mobile phases and the solvent for sample preparation. This method was validated
Ludivine Vieira-Sellaï, Mercedes Quintana, Ousmane Diop, Olivier Mercier, Sebastien Tarrit, Nawal Raimi, Alassan Ba, Benoit Maunit, Marie-Josephe Galmier   +8 more
doaj   +1 more source

Me-Better Drug Design Based on Nevirapine and Mechanism of Molecular Interactions with Y188C Mutant HIV-1 Reverse Transcriptase

Molecules, 2022
In this paper, the Y188C mutant HIV-1 reverse transcriptase (Y188CM-RT) target protein was constructed by homology modeling, and new ligands based on nevirapine (NVP) skeleton were designed by means of fragment growth. The binding activity of new ligands
Yan Wang, Aidong Wang, Jianhua Wang, Xiaoran Wu, Yijie Sun, Yan Wu   +5 more
doaj   +1 more source

Non-adherence to the single dose nevirapine regimen for the prevention of mother-to-child transmission of HIV in Bindura town, Zimbabwe: a cross-sectional analytic study

BMC Public Health, 2010
Background The Prevention of Mother to Child Transmission of HIV (PMTCT) programme was introduced at Bindura Hospital in 2003. Seven additional satellite PMTCT clinics were set up in the district to increase service coverage but uptake of PMTCT ...
Shambira Gerald N, Tshuma Clemence D, Kuonza Lazarus R, Tshimanga Mufuta   +3 more
doaj   +1 more source

Affecting factors to effectiveness of starting therapy in children with hiv infection

Журнал инфектологии, 2015
The purpose of the research – to characterize of the factors that influence the effectiveness of the starting highly activе antiretroviral therapy in children with HIV infection.Materials and methods.
V. B. Denisenko, E. N. Simovanyan
doaj   +1 more source