Results 11 to 20 of about 20,764 (191)

HLA-Cw*04 allele associated with nevirapine-induced rash in HIV-infected Thai patients [PDF]

AIDS Research and Therapy, 2009
Background A high incidence of rash has been reported in HIV-1 patients who received the anti-retroviral drug nevirapine. In addition, several studies have suggested that polymorphisms of human leukocyte antigen (HLA) genes may play important roles in ...
Tunthanathip Preecha, Prasithsirikul Wisit, Uttayamakul Sumonmal, Feangvad Siriluk, Rattanatham Tippawan, Likanonsakul Sirirat, Nakayama Emi E, Shioda Tatsuo   +7 more
doaj   +2 more sources

Determination of nevirapine in the presence of cucurbit(7)uril with a gold electrode [PDF]

Journal of Electrochemical Science and Engineering, 2014
The electrochemical oxidation of nevirapine, an anti-HIV drug, at a gold electrode was studied by voltammetric techniques. Nevirapine showed a signal that interfered with a working electrode wave.
ELÍAS BLANCO, JUAN J. PIÑA, ABEL I. BALBIN, CARMEN QUINTANA, PEDRO HERNÁNDEZ   +4 more
doaj   +5 more sources

Pharmacological and clinical evidence of nevirapine immediate- and extended-release formulations

HIV/AIDS: Research and Palliative Care, 2012
Javier Ena, Concepción Amador, Conxa Benito, Francisco PasquauHIV Unit, Hospital Marina Baixa, Villajoyosa, SpainAbstract: We reviewed the current information available on nevirapine immediate- and extended-release formulations and its role in
Ena J, Amador C, Benito C, Pasquau F
doaj   +1 more source

Electrochemical studies of nevirapine, an anti-HIV drug, and its assay in tablets and biological samples [PDF]

Journal of Electrochemical Science and Engineering, 2012
The electrochemical oxidation of nevirapine, an anti-HIV drug, at a glassy carbon electrode has been studied by voltammetric techniques. Nevirapine showed one well defined irreversible oxidation peak with a potential of 0.749 V in phosphate buffer at pH ...
JALDAPPAGARI SEETHARAMAPPA, SHANKAR NARAYAN PRASHANTH, NAGAPPA LAXMAN TERADAL   +2 more
doaj   +5 more sources

Nevirapine

Reactions Weekly, 2006
europepmc   +5 more sources

Design, Synthesis, In Silico Studies, and HIV-1 RT Inhibitory Activity of 1,3-Oxazolidine Pyrimidine Nucleoside Analogues. [PDF]

Chem Biodivers
Previously synthesized 1,3‐oxazolidine pyrimidine nucleoside analogues (S1–S6) were evaluated for HIV‐1 reverse transcriptase inhibition using molecular docking, ADMET prediction, and an in vitro colorimetric HIV‐RT assay. Compounds S4 and S5 exhibited the strongest binding affinities and moderate enzyme inhibition (IC50 = 19.27 and 22.80 µM ...
Sriharsha SN, Mohamed ZM, Mahmood AAR, Sangi SMA, Shaik S, Nagaraja S, Kumari S, Thirunavukkarasu V, Sreenivasalu PK, Islam M, Chohan MS, Biradar MS.   +11 more
europepmc   +2 more sources

Temporal shifts in antiretroviral therapy regimens and metabolic outcomes in people living with HIV: A systematic review and meta-analysis. [PDF]

HIV Med
Abstract Introduction Antiretroviral therapy (ART) for people living with HIV has led to dramatically reduced mortality and improved life expectancy. This achievement is accompanied by a higher risk for metabolic and other non‐communicable diseases. The role and contribution of various ART regimens to adverse metabolic outcomes are not fully understood.
Mahanani MR, Chit M, Mohr S, Cama I Gibernau E, Hetjens S, Winkler V, Steffen HM, Neuhann F.   +7 more
europepmc   +2 more sources

Medicinal Chemistry Aspects of Thiazole and Thiazolidine Derivatives as Fundamental Building Blocks to Design New NNRTIs Against HIV-1 Reverse Transcriptase. [PDF]

ChemMedChem
HIV‐1 reverse transcriptase (HIV‐1 RT) is a polymerase enzyme and a key target in HIV‐1 therapy. The discovery of selective HIV‐1 RT inhibitors has highlighted thiazole scaffolds and their derivatives, thiazolidine‐2‐one and thiazolidine‐2,4‐dione, as promising structures for the rational design of novel non‐nucleoside reverse transcriptase inhibitors (
da Silva Moura JA, de Melo MVG, do Nascimento DRS, Bezerra TPW, Métifiot M, Recordon-Pinson P, da Rocha Pitta MG, da Rocha Pitta MG, Pereira MC, Andreola ML.   +9 more
europepmc   +2 more sources

Dolutegravir Is Associated With Lower Odds of Gestational Diabetes Compared to Other Antiretroviral Therapy Regimens Among Pregnant Women in India: A Cross-Sectional Analysis. [PDF]

J Int AIDS Soc
ABSTRACT Introduction In non‐pregnant adults living with HIV, dolutegravir is associated with weight gain and increased type 2 diabetes risk. In pregnancy, data on the effect of dolutegravir on gestational diabetes (GDM) risk is inconclusive. Data are particularly limited in Asian populations, where diabetes risk is especially high and not always ...
Chebrolu P, Ahmed F, Tambe S, Alexander M, Raichur P, Kole A, Kante S, Kulkarni V, Gupte N, Bhosale R, Naik S, Gupta A, Brown TT, Mathad JS.   +13 more
europepmc   +2 more sources

Nevirapine plasma concentrations are associated with virologic response and hepatotoxicity in Chinese patients with HIV infection. [PDF]

PLoS ONE, 2011
BACKGROUND: Limited information is available on the relationship between nevirapine plasma concentrations and virologic response or liver toxicity in Chinese patients with HIV infection.
Jia Wang, Huijuan Kou, Qiang Fu, Yang Han, Zhifeng Qiu, Lingyan Zuo, Yanling Li, Zhu Zhu, Min Ye, Qing Ma, Taisheng Li   +10 more
doaj   +1 more source