Results 11 to 20 of about 15,487 (155)

Rejoinder to Commentaries on "A Perspective on the Appropriate Implementation of ICH E9(R1) Addendum Strategies for Handling Intercurrent Events". [PDF]

Stat Med
Statistics in Medicine, Volume 45, Issue 15-17, July 2026.
Fleming TR, Carroll KJ, Wittes JT, Emerson SS, Rothmann MD, Collins S, Levin G.   +6 more
europepmc   +2 more sources

Nevirapine Increases Sodium/Iodide Symporter-Mediated Radioiodide Uptake by Activation of TSHR/cAMP/CREB/PAX8 Signaling Pathway in Dedifferentiated Thyroid Cancer

Frontiers in Oncology, 2020
Nevirapine has been proved to be effective in inducing re-differentiation and suppressing tumor growth in several tumor cells. This study aims to investigate the therapeutic potential of nevirapine in dedifferentiated thyroid cancer (DeTC), which ...
Hongxia Shang, Junyu Zhao, Junyu Zhao, Jinming Yao, Huanjun Wang, Jianjun Dong, Lin Liao, Lin Liao   +7 more
doaj   +1 more source

Prevention of Parent to Child Transmission of HIV: Single Centre Experience of 14 years at Tertiary Care Hospital in Delhi, India [PDF]

Journal of Clinical and Diagnostic Research, 2017
Introduction: Prevention of Parent To Child Transmission (PPTCT) of HIV/AIDS is an integral component of AIDS control programme. PPTCT is an ongoing programme since last 15 years.
AG Radhika, Sonia Chawla, Sruthi Bhaskaran   +2 more
doaj   +1 more source

Review The Emerging Profile of Cross-Resistance among the Nonnucleoside HIV-1 Reverse Transcriptase Inhibitors

Viruses, 2014
Nonnucleoside reverse transcriptase inhibitors (NNRTIs) are widely used to treat HIV-1-infected individuals; indeed most first-line antiretroviral therapies typically include one NNRTI in combination with two nucleoside analogs.
Nicolas Sluis-Cremer
doaj   +1 more source

Dipyridodiazepinone derivatives; synthesis and anti HIV-1 activity

Beilstein Journal of Organic Chemistry, 2009
Ten dipyridodiazepinone derivatives were synthesized and evaluated for their anti HIV-1 reverse transcriptase activity against wild-type and mutant type enzymes, K103N and Y181C. Two of them were found to be promising inhibitors for HIV-1 RT.
Nisachon Khunnawutmanotham, Nitirat Chimnoi, Arunee Thitithanyanont, Patchreenart Saparpakorn, Kiattawee Choowongkomon, Pornpan Pungpo, Supa Hannongbua, Supanna Techasakul   +7 more
doaj   +1 more source

The antiretroviral efficacy of highly active antiretroviral therapy and plasma nevirapine concentrations in HIV-TB co-infected Indian patients receiving rifampicin based antituberculosis treatment

AIDS Research and Therapy, 2011
Background Rifampicin reduces the plasma concentrations of nevirapine in human immunodeficiency virus (HIV) and tuberculosis (TB) co-infected patients, who are administered these drugs concomitantly.
Sinha Sanjeev, Dhooria Sahajal, Kumar Sanjiv, Shah Nipam, Velpandian T, Ravi AK, Kumar Narendra, Ahmad Hafeez, Bhargwa Akshat, Chug Karan, Bumma Naresh, Chandrashekhar Rahul, Ekka Meera, Sreenivas Vishnu, Sharma Surendra K, Samantaray JC, Mitsuyasu Ronald   +16 more
doaj   +1 more source

Investigating the continuous synthesis of a nicotinonitrile precursor to nevirapine

Beilstein Journal of Organic Chemistry, 2013
2-Chloro-3-amino-4-picoline (CAPIC) is a strategic building block for the preparation of nevirapine, a widely-prescribed non-nucleosidic reverse transcriptase inhibitor for the treatment of HIV-infected patients.
Ashley R. Longstreet, Suzanne M. Opalka, Brian S. Campbell, B. Frank Gupton, D. Tyler McQuade   +4 more
doaj   +1 more source

Optimizing Identification and Care of Pregnant/Breastfeeding Women Living With HIV in Resource-Limited Settings. [PDF]

J Int AIDS Soc
ABSTRACT Introduction Since the mid‐1990s, there have been major advances in diagnosing and providing antiretroviral therapy (ART) for pregnant women living with HIV (WLWH) in both resource‐rich and resource‐limited settings. Initial progress was based on the 1994 landmark perinatal trial, which showed 67% reduction in vertical transmission among ...
Fowler MG, Chou VB, Musoke P.
europepmc   +2 more sources

Green HPLC quantification method of lamivudine, zidovudine and nevirapine with identification of related substances in tablets

Green Chemistry Letters and Reviews, 2022
A green HPLC method for lamivudine (3TC), zidovudine (AZT) and nevirapine (NVP) determination in fixed-dose combination tablets was developed using ethanol as both one of the mobile phases and the solvent for sample preparation. This method was validated
Ludivine Vieira-Sellaï, Mercedes Quintana, Ousmane Diop, Olivier Mercier, Sebastien Tarrit, Nawal Raimi, Alassan Ba, Benoit Maunit, Marie-Josephe Galmier   +8 more
doaj   +1 more source

Non-adherence to the single dose nevirapine regimen for the prevention of mother-to-child transmission of HIV in Bindura town, Zimbabwe: a cross-sectional analytic study

BMC Public Health, 2010
Background The Prevention of Mother to Child Transmission of HIV (PMTCT) programme was introduced at Bindura Hospital in 2003. Seven additional satellite PMTCT clinics were set up in the district to increase service coverage but uptake of PMTCT ...
Shambira Gerald N, Tshuma Clemence D, Kuonza Lazarus R, Tshimanga Mufuta   +3 more
doaj   +1 more source