Results 31 to 40 of about 20,764 (191)
The bioavailability of a drug is usually determined by its aqueous solubility and lipid permeability. Nevirapine is an antiretroviral drug that belongs to the BCS II with poor solubility but high permeability.
Ochen Faithfulness +2 more
core +1 more source
Effect of rifampicin-based antitubercular therapy on nevirapine plasma concentrations in South African adults with HIV-associated tuberculosis [PDF]
Includes bibliographical references.Sub-Saharan Africa is overwhelmed by dual epidemics of human immunodeficiency virus (HIV) and tuberculosis (TB) infection.
Cohen, Karen
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Nevirapine Hepatotoxicity: Case Report and Discussion [PDF]
Nevirapine (viramune) is a nonnucleoside reverse transcriptase inhibitor commonly used in combination with other antiretroviral medicines in the treatment of HIV/AIDS.
Baichi, Matt, Matt Baichi, null null
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Nevirapine- and efavirenz-associated hepatotoxicity under programmatic conditions in Kenya and Mozambique. [PDF]
To describe the frequency, risk factors, and clinical signs and symptoms associated with hepatotoxicity (HT) in patients on nevirapine- or efavirenz-based antiretroviral therapy (ART), we conducted a retrospective cohort analysis of patients attending ...
Ford, N P +6 more
core +1 more source
ABSTRACT Generation of CAR‐T cell therapies relies predominantly on lentiviral vectors (LVs). As in vivo CAR‐T trials progress, demand for larger quantities of higher‐potency LV is expected. However, primary capture by anion‐exchange chromatography (AIEX) remains a major manufacturing bottleneck from use of adsorbents not tailored to LVs, leading to ...
George Pamenter +10 more
wiley +1 more source
Anti-Retroviral Treatment in dr. Sardjito Central General Hospital Yogyakarta
Background: Adverse cutaneous drug reactions (ACDRs) affect 2-3% of hospitalized patients globally, wherein approximately 2% (1 in 1,000 cases) accounted for a severe form of cutaneous drug reactions.
Labitta Pachira Aquaira +2 more
doaj +1 more source
Stabilization of specific crystal polymorphs of an active pharmaceutical ingredient is crucial for preventing uncontrollable interconversion of various crystalline forms, which affects physicochemical properties as well as physiological activity.
Mariya A. Kryukova +4 more
doaj +1 more source
Clinical significance of acute kidney injury in idiosyncratic drug‐induced liver injury: a multicentric propensity scores matched study. Evidence about the role of acute kidney injury (AKI) in idiosyncratic drug‐induced liver injury (DILI) is still scarce.
José María Pinazo‐Bandera +15 more
wiley +1 more source
IntroductionA reversed-phase high-performance liquid chromatographic (RP-HPLC) method was developed and validated for the quantitation of nevirapine (NVP) in bulk drug, commercial tablets, and niosome formulations using an Analytical Quality by Design ...
Bwalya A. Witika, Roderick B. Walker
doaj +1 more source
IMPROVING ANTIRETROVIRAL THERAPY IN CHILDREN WITH HIV INFECTION
The objective — to characterize the effectiveness of different schemes of antiretroviral therapy in children with HIV infection and on the basis of the obtained data to improve of the disease treatment.Patients and Methods: A clinical, immunological and ...
V. B. Denisenko, E. N. Simovanyan
doaj +1 more source

