Results 51 to 60 of about 15,487 (155)
Possible hepatotoxic consequence of nevirapine use in juvenile albino rats [PDF]
Journal of Pharmacy & Pharmacognosy Research, 2017 Context: Nevirapine (NVP) is used in human immunodeficiency virus exposed neonates. This could present safety concern due to decreased liver metabolizing enzymes activity and renal clearance in neonates.
Elias Adikwu, Bonsome Bokolo
doaj
HIV Research & Clinical Practice, 2019 Background: To evaluate long term outcomes in patients maintaining a NVP based regimen for more than 10 years. Materials and methods: Retrospective, multicenter, cohort study including virologically suppressed patients, currently receiving a NVP-based ...
Juan Tiraboschi +5 more
doaj +1 more source
Unveiling the Power of Deuterium in Drug Discovery: A Comprehensive Overview
MedComm, Volume 7, Issue 6, June 2026.The role of deuterium replacement in drug discovery, its progress, opportunities, and challenges. ABSTRACT Deuterium, the heavy isotope of hydrogen, has unfolded as a cornerstone in modern drug discovery due to its potential to influence metabolic stability and pharmacokinetic behavior.
Mukta Lele +7 more
wiley +1 more source
The Pan African Medical Journal, 2018 INTRODUCTION: Although combined Anti-Retroviral Therapy (cART) has improved the quality of life and survival in people living with HIV-AIDS (PLWHA), there have been reports of increased non-AIDS related co-morbidities such as coagulopathies.
Richard Kobina Dadzie Ephraim +6 more
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2'-Deoxythymidine Adducts from the Anti-HIV Drug Nevirapine
Molecules, 2013 Nevirapine (NVP) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used against HIV-1. Currently, NVP is the most widely used anti-HIV drug in developing countries, both in combination therapy and to prevent mother-to-child transmission of HIV.
M. Matilde Marques +4 more
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The impact of accumulating immune adaptation in circulating strains of HIV‐1
HIV Medicine, Volume 27, Issue 6, Page 918-934, June 2026.Abstract Background Mutations in human immunodeficiency virus type 1 (HIV‐1) enable the virus to evade recognition and killing by human leucocyte antigen (HLA)‐restricted T cells. These viral adaptations are specific to the HLA type of individuals and are therefore evident as HLA allele‐HIV sequence associations at the population level. Most studies of
Marwah Al‐kaabi +7 more
wiley +1 more source
Indian Dermatology Online Journal, 2014 Nevirapine, a non-nucleoside reverse transcriptase inhibitor (NNRTI) is one of the important components of highly active antiretroviral therapy. It is sometimes associated with life-threatening adverse reactions.
Leelavathy Budamakuntla +4 more
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Chemistry–Methods, Volume 6, Issue 5, May 2026.Fluorescence experiments to estimate the association constant avoiding the Inner Filter Effect on HSA titration with ligand. An excursus of the principal methodologies to identify and correct the IFE artifact. Fluorescence‐based methods are widely used to assess protein–ligand and protein–protein interactions.
Filippo Savini +4 more
wiley +1 more source
Chemical and Toxicological Analysis of Antiretroviral Drugs
Разработка и регистрация лекарственных средств, 2019 Introduction. Human Immunodeficiency Virus (HIV) is one of the main socially significant infection all over the world. HIV-positive patients take medical care, including antiretroviral drugs (ARVs) pharmacotherapy.
T. N. Komarov +7 more
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SPECTROPHOTOMETRIC DETERMINATION OF NEVIRAPINE USING TETRATHIOCYANATOCOBALT(II) ION AS A REAGENT
Eclética Química, 2018 A simple and rapid spectrophotometric method for the determination of nevirapine is described. The method is based on the reaction of nevirapine with tetrathiocyanatocobalt(II) ion in buffer of pH 4 to form the corresponding complex. Beer’s law is obeyed
T. V. Badiadka, Badiadka Narayana
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