Results 51 to 60 of about 20,764 (191)

Safety of Prenatal Anti‐Infective Use and Offspring Outcomes: A Panoramic Assessment by Indication, Drug Class, and Exposure Characteristics

iMetaMed, Volume 2, Issue 3, September 2026.
Based on the comprehensive, panoramic assessment of the safety of prenatal anti‐infective use across indications, drug classes, and exposure characteristics, potential safety signals associated with prenatal exposure to several widely used anti‐infective drug classes were identified, including macrolides, metronidazole, tetracyclines, sulfonamides ...
Wenling Wang, Yuezhen Li, Chunrong Liu, Chen Chen, Meng Chen, Lehana Thabane, Xin Sun, Jing Tan   +7 more
wiley   +1 more source

FORMULATION AND EVALUATION OF NEVIRAPINE MUCOADHESIVE MICROSPHERES [PDF]

, 2015
Objective: The objective of the present research was to formulate and evaluate HPMC K4M, HPMC K100, and Carbopol 940 Mucoadhesive microspheres in combination with sodium alginate for controlling release of Nevirapine.
Ararath, Dasari, Velmurugan, Sellappan
core   +1 more source

Nevirapine versus ritonavir-boosted lopinavir for HIV-infected children [PDF]

, 2012
CITATION: Violari, A. et al. 2012. Nevirapine versus ritonavir-boosted lopinavir for HIV-infected children. New England Journal of Medicine, 366:2380-2389, doi:10.1056/NEJMoa1113249.The original publication is available at https://www.nejm.orgBACKGROUND:
Paed, F. C., Eshleman, Susan H., Purdue, Lynette, Mujuru, Hilda A., Kamthunzi, Portia, Palumbo, Paul, Petzold, Elizabeth, Lindsey, Jane C., Bobat, Raziya, Cotton, Mark F., Chi, Benjamin H., Millar, Linda, Barlow-Mosha, Linda, Moultrie, Harry, Khadse, Sandhya, Abrams, Elaine J., Hughes, Michael D., Mofenson, Lynne M., Violari, Avy, Schimana, Werner, Jean-Philippe, Patrick   +20 more
core   +1 more source

The impact of choice of NNRTI on short-term treatment outcomes among HIV-infected patients prescribed tenofovir and lamivudine in Johannesburg, South Africa. [PDF]

PLoS ONE, 2013
Recent WHO guidelines for resource-limited settings recommend tenofovir in first-line antiretroviral therapy (ART) yet there are suggestions that patients receiving nevirapine with tenofovir have worse outcomes than those receiving efavirenz.
Kate Shearer, Matthew P Fox, Mhairi Maskew, Rebecca Berhanu, Lawrence Long, Ian Sanne   +5 more
doaj   +1 more source

Perbandingan Penggunaan Efavirenz dan Nevirapine Terhadap Kolesterol LDL Pasien HIV/AIDS

Pharmaceutical Sciences and Research, 2019
Gangguan metabolik lipid merupakan kondisi yang sering ditemukan pada pasien HIV (Human Immunodeficiency Virus)/AIDS (Acquired Immuno Deficiency Syndrome) pada pasien yang menggunakan antiretroviral (ARV) lini pertama seperti efavirenz dan nevirapine ...
Anggriani Yusi, Evy Yunihastuti, Yulia Trisna, Ade Rosanti, Reise Manninda, Rifka Annisa   +5 more
doaj   +1 more source

Comparative durability of nevirapine versus efavirenz in first-line regimens during the first year of initiating antiretroviral therapy among Swaziland HIV-infected adults

The Pan African Medical Journal, 2013
Nevirapine (NVP) and Efavirenz (EFV) have generally comparable clinical and virologic efficacy. However, data comparing NVP durability to EFV are imprecise.
Simbarashe Takuva, Denise Evans, Khangelani Zuma, Velephi Okello, Goedele Louwagie   +4 more
doaj   +1 more source

HIV drug resistance and treatment success in the Republic of Congo: Implications for optimized treatment

HIV Medicine, Volume 27, Issue 9, Page 1421-1433, September 2026.
Abstract Objectives Increasing rates of HIV‐1 drug resistance (HIVDR) threaten the effectiveness of antiretroviral therapy (ART) programmes in sub‐Saharan Africa, particularly among children, adolescents and young adults, who face limited treatment options.
Dominic Rauschning, Arcy Marcelin Elenga Ike, Johanna Holterhoff, Amira Stockinger, Darrel Ornelle Elion Assiana, Claujens Chastel Mfoutou Mapanguy, Freisnel Hermeland Mouzinga, Carola Horn, Isabelle Suarez, Ferdinand Heyn, Diane Alexia Fila, Hubert Banguissa, Fabien Roch Niama, Donatien Moukassa, Eva Heger, Francine Ntoumi, Clara Lehmann   +16 more
wiley   +1 more source

Associations of modern initial antiretroviral therapy regimens with all-cause mortality in people living with HIV in resource-limited settings: a retrospective multicenter cohort study in China

Nature Communications, 2023
Despite the proven virological advantages, there remains some controversy regarding whether first-line integrase strand transfer inhibitors (INSTIs)-based antiretroviral therapy (ART) contributes to reducing mortality of people living with HIV (PLHIV) in
Xinsheng Wu, Guohui Wu, Ping Ma, Rugang Wang, Linghua Li, Yuanyi Chen, Junjie Xu, Yuwei Li, Quanmin Li, Yuecheng Yang, Lijing Wang, Xiaoli Xin, Ying Qiao, Gengfeng Fu, Xiaojie Huang, Bin Su, Tong Zhang, Hui Wang, Huachun Zou   +18 more
doaj   +1 more source

A Systematic Review of Published Physiologically Based Pharmacokinetic Models for Drug Excretion Into Human Breastmilk: Knowledge Gaps and Opportunities to Optimize Reporting and Modeling Practices

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 8, August 2026.
ABSTRACT Physiologically based pharmacokinetic (PBPK) modeling is increasingly used to predict infant exposure to medications via breast milk. Existing guidance on reporting of PBPK modeling analyses is unstructured and nonbinding to researchers. We evaluated reporting practices and modeling approaches in published PBPK modeling studies.
Joshua Kiptoo, Davies Otieno, Kenta Yoshida, Neel Deferm, Aida Nakayiwa Kawuma, Francis Williams Ojara, Adeniyi Olagunju, Jackson K. Mukonzo, Catriona Waitt   +8 more
wiley   +1 more source

Efavirenz challenge in patients with nevirapine induced Stevens-Johnson Syndrome

Southern African Journal of Infectious Diseases, 2016
Background: Non-nucleoside reverse transcriptase inhibitors (NNRTI) are recommended as part of first-line treatment by the World Health Organisation (WHO) for antiretroviral treatment (ART) naïve subjects.
Thandekile C. Manzini, Bernadett I. Gosnell, Melanie-Anne A. John, Mahomed Y. S. Moosa   +3 more
doaj   +1 more source