Results 61 to 70 of about 19,421 (203)

The impact of choice of NNRTI on short-term treatment outcomes among HIV-infected patients prescribed tenofovir and lamivudine in Johannesburg, South Africa. [PDF]

PLoS ONE, 2013
Recent WHO guidelines for resource-limited settings recommend tenofovir in first-line antiretroviral therapy (ART) yet there are suggestions that patients receiving nevirapine with tenofovir have worse outcomes than those receiving efavirenz.
Kate Shearer, Matthew P Fox, Mhairi Maskew, Rebecca Berhanu, Lawrence Long, Ian Sanne   +5 more
doaj   +1 more source

The impact of accumulating immune adaptation in circulating strains of HIV‐1

HIV Medicine, Volume 27, Issue 6, Page 918-934, June 2026.
Abstract Background Mutations in human immunodeficiency virus type 1 (HIV‐1) enable the virus to evade recognition and killing by human leucocyte antigen (HLA)‐restricted T cells. These viral adaptations are specific to the HLA type of individuals and are therefore evident as HLA allele‐HIV sequence associations at the population level. Most studies of
Marwah Al‐kaabi, Alison Castley, Pooja Deshpande, Abha Chopra, David Nolan, Simon Mallal, Mina John, Silvana Gaudieri   +7 more
wiley   +1 more source

Perbandingan Penggunaan Efavirenz dan Nevirapine Terhadap Kolesterol LDL Pasien HIV/AIDS

Pharmaceutical Sciences and Research, 2019
Gangguan metabolik lipid merupakan kondisi yang sering ditemukan pada pasien HIV (Human Immunodeficiency Virus)/AIDS (Acquired Immuno Deficiency Syndrome) pada pasien yang menggunakan antiretroviral (ARV) lini pertama seperti efavirenz dan nevirapine ...
Anggriani Yusi, Evy Yunihastuti, Yulia Trisna, Ade Rosanti, Reise Manninda, Rifka Annisa   +5 more
doaj   +1 more source

Methods of Inner Filter Effect Correction in Fluorescence Measurements of Protein–Ligand Association: A Re‐Examination of the Association of Anti‐HIV Drugs to Serum Albumin

Chemistry–Methods, Volume 6, Issue 5, May 2026.
Fluorescence experiments to estimate the association constant avoiding the Inner Filter Effect on HSA titration with ligand. An excursus of the principal methodologies to identify and correct the IFE artifact. Fluorescence‐based methods are widely used to assess protein–ligand and protein–protein interactions.
Filippo Savini, Sara Bobone, Lorenzo Stella, Daniela Roversi, Alessio Bocedi   +4 more
wiley   +1 more source

Comparative durability of nevirapine versus efavirenz in first-line regimens during the first year of initiating antiretroviral therapy among Swaziland HIV-infected adults

The Pan African Medical Journal, 2013
Nevirapine (NVP) and Efavirenz (EFV) have generally comparable clinical and virologic efficacy. However, data comparing NVP durability to EFV are imprecise.
Simbarashe Takuva, Denise Evans, Khangelani Zuma, Velephi Okello, Goedele Louwagie   +4 more
doaj   +1 more source

This Is Not a Myeloproliferative Neoplasm…

Pediatric Blood &Cancer, Volume 73, Issue 7, July 2026.
Stephanie Juané Kennedy
wiley   +1 more source

PKRxiv: A Best Practice Model for Advancing Pharmacoequity Through Open Pharmacokinetic Data Sharing

Clinical Pharmacology &Therapeutics, Volume 119, Issue 5, Page 1235-1248, May 2026.
Model‐informed drug development is increasingly integrated across the drug development continuum, enabling more efficient, cost‐effective, and targeted trials while reducing reliance on animal studies. Achieving pharmacoequity requires not only equitable access to medicines but also to the data and knowledge that inform drug development and regulatory ...
Shakir Atoyebi, Prajith Venkatasubramanian, Abdulafeez Akinloye, Oluwasegun Eniayewu, Brookie M. Best, Laura Else, Adeniyi Olagunju   +6 more
wiley   +1 more source

Therapeutic drug monitoring of nevirapine in resource-limited settings. [PDF]

, 2008
Contains fulltext : 70637.pdf (Publisher’s version ) (Open Access)BACKGROUND: We developed a simple and inexpensive thin-layer chromatography (TLC) assay for semiquantitative detection of saliva concentrations of nevirapine in resource ...
Burger, D.M., Wolters, L.R., Ewijk-Beneken Kolmer, E.W.J. van, Droste, J.A.H., L'homme, R.F.A., Schimana, W., Muro, E.P.   +6 more
core   +1 more source

Associations of modern initial antiretroviral therapy regimens with all-cause mortality in people living with HIV in resource-limited settings: a retrospective multicenter cohort study in China

Nature Communications, 2023
Despite the proven virological advantages, there remains some controversy regarding whether first-line integrase strand transfer inhibitors (INSTIs)-based antiretroviral therapy (ART) contributes to reducing mortality of people living with HIV (PLHIV) in
Xinsheng Wu, Guohui Wu, Ping Ma, Rugang Wang, Linghua Li, Yuanyi Chen, Junjie Xu, Yuwei Li, Quanmin Li, Yuecheng Yang, Lijing Wang, Xiaoli Xin, Ying Qiao, Gengfeng Fu, Xiaojie Huang, Bin Su, Tong Zhang, Hui Wang, Huachun Zou   +18 more
doaj   +1 more source

KSHV Genome in Saliva, Whole Blood and Kaposi's Sarcoma Biopsy Specimens in Republic of Congo: Phylogenetic Analysis and an APOBEC3B Mutational Signature

Journal of Medical Virology, Volume 98, Issue 5, May 2026.
ABSTRACT Kaposi's sarcoma‐associated herpesvirus (KSHV) has been associated with a variety of diseases and is endemic in Sub‐Saharan Africa. We performed KSHV‐whole‐genome analysis and search for APOBEC‐editing to describe genetic diversity in samples issued from an endemic region.
Gervillien Arnold Malonga, Valentin Leducq, Antoine Fauchois, Dimitry Moudiongui Mboungou Malanda, Patrina Joseph Iloukou Mayakia, Juthèce Private Malanda‐Kiminou, Ferdinand Emaniel Brel Got, Fabien Gaël Mouamba, Vincent Calvez, Jean Felix Peko, Anne‑Geneviève Marcelin, Aude Jary   +11 more
wiley   +1 more source