Results 61 to 70 of about 39,721 (242)

Delay of cell growth and loss of stemness by inhibition of reverse transcription in human mesenchymal stem cells derived from dental tissue

Animal Cells and Systems, 2019
The present study investigated the cellular properties in the dental tissue-derived mesenchymal stem cells (DSCs) exposed to nevirapine (NVP), an inhibitor of reverse transcriptase (RTase).
Won-Cheol Lee, Dae-Young Kim, Mi-Jeong Kim, Hyeon-Jeong Lee, Dinesh Bharti, Sung-Ho Lee, Young-Hoon Kang, Gyu-Jin Rho, Byeong-Gyun Jeon   +8 more
doaj   +1 more source

Implementing a tenofovir-based first-line regimen in rural Lesotho: clinical outcomes and toxicities after two years. [PDF]

, 2011
The latest World Health Organization guidelines recommend replacing stavudine with tenofovir or zidovudine in first-line antiretroviral therapy in resource-limited settings.
Birkus, Brinkman, Callaghan, Cohen, Davidson, Ford, Gallant, Gallant, Grim, Hawkins, Mills, Pozniak, Stone   +12 more
core   +2 more sources

PKRxiv: A Best Practice Model for Advancing Pharmacoequity Through Open Pharmacokinetic Data Sharing

Clinical Pharmacology &Therapeutics, Volume 119, Issue 5, Page 1235-1248, May 2026.
Model‐informed drug development is increasingly integrated across the drug development continuum, enabling more efficient, cost‐effective, and targeted trials while reducing reliance on animal studies. Achieving pharmacoequity requires not only equitable access to medicines but also to the data and knowledge that inform drug development and regulatory ...
Shakir Atoyebi, Prajith Venkatasubramanian, Abdulafeez Akinloye, Oluwasegun Eniayewu, Brookie M. Best, Laura Else, Adeniyi Olagunju   +6 more
wiley   +1 more source

Effect of exposure to clinic-based health education interventions on behavioural intention to prevent mother-to-child transmission of HIV infection

SAHARA-J, 2006
HIV and AIDS incidence among infants in South Africa is on the increase. The uptake of prevention of mother-to-child transmission (PMTCT) interventions is often said to be dependent on the beliefs and educational needs of those requiring PMTCT services ...
Jude Igumbor, Supa Pengpid, Larry Obi
doaj   +1 more source

KSHV Genome in Saliva, Whole Blood and Kaposi's Sarcoma Biopsy Specimens in Republic of Congo: Phylogenetic Analysis and an APOBEC3B Mutational Signature

Journal of Medical Virology, Volume 98, Issue 5, May 2026.
ABSTRACT Kaposi's sarcoma‐associated herpesvirus (KSHV) has been associated with a variety of diseases and is endemic in Sub‐Saharan Africa. We performed KSHV‐whole‐genome analysis and search for APOBEC‐editing to describe genetic diversity in samples issued from an endemic region.
Gervillien Arnold Malonga, Valentin Leducq, Antoine Fauchois, Dimitry Moudiongui Mboungou Malanda, Patrina Joseph Iloukou Mayakia, Juthèce Private Malanda‐Kiminou, Ferdinand Emaniel Brel Got, Fabien Gaël Mouamba, Vincent Calvez, Jean Felix Peko, Anne‑Geneviève Marcelin, Aude Jary   +11 more
wiley   +1 more source

Pharmacological and clinical evidence of nevirapine immediate- and extended-release formulations

HIV/AIDS: Research and Palliative Care, 2012
Javier Ena, Concepción Amador, Conxa Benito, Francisco PasquauHIV Unit, Hospital Marina Baixa, Villajoyosa, SpainAbstract: We reviewed the current information available on nevirapine immediate- and extended-release formulations and its role in
Ena J, Amador C, Benito C, Pasquau F
doaj  

Weight gain at 3 months of antiretroviral therapy is strongly associated with survival: evidence from two developing countries [PDF]

, 2009
BACKGROUND: In developing countries, access to laboratory tests remains limited, and the use of simple tools such as weight to monitor HIV-infected patients treated with antiretroviral therapy should be evaluated.
Arnaud Fontanet, Bagchi, Bisson, Bonard, Bonnet, Calmy, Christine Genevier, Diggle, Elisabeth Szumilin, Erikstrup, Etard, Ferradini, Ferradini, Gilks, Harries, Ivers, Jerene, Laurent Ferradini, Madec, Malvy, Mar Pujades, Paton, Saghayam, San Lio, Severe, Shetty, Shikuma, Silva, Spacek, Stringer, Suna Balkan, Tang, Van Damme, Yoann Madec   +33 more
core   +3 more sources

A Review on Medicinal Chemistry and Biological Activity of Dihydropyrimidinones Against HIV

Archiv der Pharmazie, Volume 359, Issue 4, April 2026.
This article presents the latest advances in the development of dihydropyrimidinone (DHPM) derivatives as promising candidates against HIV. By exploring their interactions with essential viral targets and highlighting innovative compounds with potent antiviral activity, we provide an updated perspective on the opportunities for new antiretroviral ...
Debora I. Leite, Fernando B. Macedo, Murilo Marinho de C. Lima, Isabelle S. Brum, Jonathan Fragoso Miranda de Oliveira, Ana Clara S. Costa, Stella C. Duarte, Sarah Moon, Stefany de Castro B. Moura, Andressa P. de Oliveira, Nubia Boechat, Monica M. Bastos   +11 more
wiley   +1 more source

Interaction of Nevirapine with the Peptide Binding Groove of HLA-DRB1*01:01 and Its Effect on the Conformation of HLA-Peptide Complex

International Journal of Molecular Sciences, 2018
Human leukocyte antigen (HLA)-DRB1*01:01 has been shown to be involved in nevirapine-induced hepatic hypersensitivity reactions. In the present study, in silico docking simulations and molecular dynamics simulations were performed to predict the ...
M. Hirasawa, K. Hagihara, K. Abe, O. Ando, N. Hirayama   +4 more
semanticscholar   +1 more source

Antiretroviral treatment outcomes in patients who received rifampicin together with nevirapine or efavirenz. [PDF]

, 2008
Cape Town TB ...
Boulle, A, Cohen, Karen, Goemaere, Eric
core   +1 more source