Results 41 to 50 of about 39,721 (242)

Green HPLC quantification method of lamivudine, zidovudine and nevirapine with identification of related substances in tablets

Green Chemistry Letters and Reviews, 2022
A green HPLC method for lamivudine (3TC), zidovudine (AZT) and nevirapine (NVP) determination in fixed-dose combination tablets was developed using ethanol as both one of the mobile phases and the solvent for sample preparation. This method was validated
Ludivine Vieira-Sellaï, Mercedes Quintana, Ousmane Diop, Olivier Mercier, Sebastien Tarrit, Nawal Raimi, Alassan Ba, Benoit Maunit, Marie-Josephe Galmier   +8 more
doaj   +1 more source

Differences in Nevirapine Biotransformation as a Factor for its Sex-Dependent Dimorphic Profile of Adverse Drug Reactions [PDF]

, 2014
OBJECTIVES: Nevirapine is widely used for the treatment of HIV-1 infection; however, its chronic use has been associated with severe liver and skin toxicity.
A. M. M. Antunes, A. T. Marinho, Ades, Almond, Alnouti, Anderson, Antinori, Antunes, Antunes, Antunes, Antunes, Chen, Dailly, De Lazzari, de Maat, de Maat, Dong, Dunn II, E. C. Monteiro, Erickson, Floridia, Fuda, Glatt, Hall, Ho, Kappelhoff, Kiertiburanakul, Lehr, Liu, Lockman, M. M. Marques, Martin, Medrano, Michaud, Miller, Ofotokun, P. M. Rodrigues, Regazzi, Riska, S. A. Pereira, S. G. Harjivan, Scandlyn, Sinues, Stohr, Suzuki, T. Branco, Taiwo, Thompson, Tsoi, U. Caixas, Umeh, Venkatachalam, Voskuhl, Wu, Xu, Xu, Yuan   +56 more
core   +3 more sources

Me-Better Drug Design Based on Nevirapine and Mechanism of Molecular Interactions with Y188C Mutant HIV-1 Reverse Transcriptase

Molecules, 2022
In this paper, the Y188C mutant HIV-1 reverse transcriptase (Y188CM-RT) target protein was constructed by homology modeling, and new ligands based on nevirapine (NVP) skeleton were designed by means of fragment growth. The binding activity of new ligands
Yan Wang, Aidong Wang, Jianhua Wang, Xiaoran Wu, Yijie Sun, Yan Wu   +5 more
doaj   +1 more source

A Drug Dosage Table is a Useful Tool to Facilitate Prescriptions of Antiretroviral Drugs for Children in Thailand. [PDF]

, 2005
Scaling up of antiretroviral treatment (ART) for children in countries like Thailand will require decentralization and management by non-specialist doctors.
Eksaengsri, A, Frederix, K, Petdachai, W, Ponnet, M, Wilson, D, Zachariah, R   +5 more
core   +2 more sources

Drug resistance outcomes of long-term ART with tenofovir disoproxil fumarate in the absence of virological monitoring [PDF]

, 2018
Objectives: The resistance profiles of patients receiving long-term ART in sub-Saharan Africa have been poorly described. This study obtained a sensitive assessment of the resistance patterns associated with long-term tenofovir-based ART in a ...
Appiah, Lambert T, Beloukas, Apostolos, Chadwick, David, Geretti, Anna Maria, Phillips, Richard O, Ruggiero, Alessandra, Sarfo, Fred S, Smith, Colette, Stockdale, Alexander J, Villa, Giovanni   +9 more
core   +3 more sources

Clinical and genetic factors associated with increased risk of severe liver toxicity in a monocentric cohort of HIV positive patients receiving nevirapine-based antiretroviral therapy

BMC Infectious Diseases, 2018
BackgroundNevirapine has been used as antiretroviral agent since early ‘90. Although nevirapine is not currently recommended in initial anti-HIV regimens, its use remains consistent in a certain number of HIV-1-positive subjects.
A. Giacomelli, A. Riva, F. S. Falvella, Maria Letizia Oreni, D. Cattaneo, S. Cheli, Giulia Renisi, V. Di Cristo, Angelica Lupo, E. Clementi, S. Rusconi, M. Galli, A. Ridolfo   +12 more
semanticscholar   +1 more source

Personalizing HIV therapy, mission impossible? [PDF]

, 2012
Sustained HIV suppression depends on a number of factors including therapy adherence, management of side effects, viral resistance and individual characteristics of patients and therapeutic settings.
Hentig, Nils von
core   +1 more source

Affecting factors to effectiveness of starting therapy in children with hiv infection

Журнал инфектологии, 2015
The purpose of the research – to characterize of the factors that influence the effectiveness of the starting highly activе antiretroviral therapy in children with HIV infection.Materials and methods.
V. B. Denisenko, E. N. Simovanyan
doaj   +1 more source

Effectiveness of highly active antiretroviral therapy in HIV-positive children: evaluation at 12 months in a routine program in Cambodia. [PDF]

, 2007
OBJECTIVE: Increasing access to highly active antiretroviral therapy to reach all those in need in developing countries (scale up) is slowly expanding to HIV-positive children, but documented experience remains limited. We aimed to describe the clinical,
Akao, K, Ford, N, Gupta, J, Janssens, B, Nerrienet, E, Nouhin, J, Raleigh, B, Soeung, S, Te, V, Vun, M   +9 more
core   +2 more sources

Anti-Retroviral Treatment in dr. Sardjito Central General Hospital Yogyakarta

Berkala Ilmu Kesehatan Kulit dan Kelamin (Periodical of Dermatology and Venerology)
Background: Adverse cutaneous drug reactions (ACDRs) affect 2-3% of hospitalized patients globally, wherein approximately 2% (1 in 1,000 cases) accounted for a severe form of cutaneous drug reactions.
Labitta Pachira Aquaira, Sri Awalia Febriana, Nurwestu Rusetiyanti   +2 more
doaj   +1 more source