Results 41 to 50 of about 19,421 (203)

Nevirapine versus Efavirenz for patients co-infected with HIV and Tuberculosis: A Randomised Non-Inferiority Trial

, 2013
BACKGROUND: In countries with a high incidence of HIV and tuberculosis co-infection, nevirapine and efavirenz are widely used as antiretroviral therapy but both interact with antituberculosis drugs. We aimed to compare efficacy and safety of a nevirapine-
Nilesh Bhatt, Rui Bastos, Maryline Bonnet, Jani, Ilesh, Elizabete Nunes, Sobry, Agnès, Ilesh Jani, Baudin, Elisabeth, Silva, Carlota, Michon, Christophe, Bastos, Rui, Christophe Michon, Calmy, Alexandra, Carlota Silva, Nunes, Elizabete, Agnès Sobry, Bonnet, Maryline, Alexandra Calmy, Taburet, Anne-Marie, Bhatt, Nilesh, Rouzioux, Christine, Laura Ciaffi, Elisabeth Baudin, Ciaffi, Laura, Anne-Marie Taburet, Christine Rouzioux   +25 more
core   +1 more source

The use of QbD for the development and validation of a stability-indicating RP-HPLC method for the quantitation of nevirapine in bulk, tablet and niosome formulations

Frontiers in Analytical Science
IntroductionA reversed-phase high-performance liquid chromatographic (RP-HPLC) method was developed and validated for the quantitation of nevirapine (NVP) in bulk drug, commercial tablets, and niosome formulations using an Analytical Quality by Design ...
Bwalya A. Witika, Roderick B. Walker
doaj   +1 more source

New Crystal Forms for Biologically Active Compounds. Part 1: Noncovalent Interactions in Adducts of Nevirapine with XB Donors

Crystals, 2019
Stabilization of specific crystal polymorphs of an active pharmaceutical ingredient is crucial for preventing uncontrollable interconversion of various crystalline forms, which affects physicochemical properties as well as physiological activity.
Mariya A. Kryukova, Alexander V. Sapegin, Alexander S. Novikov, Mikhail Krasavin, Daniil M. Ivanov   +4 more
doaj   +1 more source

IMPROVING ANTIRETROVIRAL THERAPY IN CHILDREN WITH HIV INFECTION

Детские инфекции (Москва), 2018
The objective — to characterize the effectiveness of different schemes of antiretroviral therapy in children with HIV infection and on the basis of the obtained data to improve of the disease treatment.Patients and Methods: A clinical, immunological and ...
V. B. Denisenko, E. N. Simovanyan
doaj   +1 more source

Unintended Consequences of Life‐Saving Pharmaceutical Innovations: How HAART Led to the Resurgence of Syphilis

Health Economics, Volume 35, Issue 7, Page 1118-1130, July 2026.
ABSTRACT Syphilis, a sexually transmitted infection that can lead to serious health complications, was almost eliminated in the United States by 2000. But since then, its incidence began to increase, recently reaching a 60‐year peak. We suggest that the introduction of the highly active antiretroviral therapy (HAART) drug regimen, which transformed HIV
David Beheshti, Scott Cunningham, Nir Eilam   +2 more
wiley   +1 more source

Channel inclusion of primary alcohols in isostructural solvates of the antiretroviral nevirapine: an X-ray and thermal analysis study

, 2010
X-ray structural and thermoanalytical data for a series of solvates 2–7 of the anti-HIV drug nevirapine containing primary alcohols CH3(CH2)nOH with n = 2–7 are reported.
Stieger, Nicole, Samsodien, Halima, Wessels, Johanna C., Caira, Mino R., Liebenberg, Wilna   +4 more
core   +1 more source

Delay of cell growth and loss of stemness by inhibition of reverse transcription in human mesenchymal stem cells derived from dental tissue

Animal Cells and Systems, 2019
The present study investigated the cellular properties in the dental tissue-derived mesenchymal stem cells (DSCs) exposed to nevirapine (NVP), an inhibitor of reverse transcriptase (RTase).
Won-Cheol Lee, Dae-Young Kim, Mi-Jeong Kim, Hyeon-Jeong Lee, Dinesh Bharti, Sung-Ho Lee, Young-Hoon Kang, Gyu-Jin Rho, Byeong-Gyun Jeon   +8 more
doaj   +1 more source

Maternal Health and Sociodemographic Characteristics Influence Infant Growth to 24 Months in the Tunza Mwana Cohort: A Prospective Cohort Study

Maternal &Child Nutrition, Volume 22, Issue 3, July 2026.
ABSTRACT Upstream pathways influencing child growth are complex. Weight‐for‐age z‐score (WAZ) reflects both ponderal and linear growth and can identify children at high mortality risk. Using data from a prospective cohort of 326 mother‐child pairs in Kenya, we evaluated whether associations between maternal exposures and child growth outcomes in early ...
David Taylor Hendrixson, Ruchi Tiwari, Philip James, Zulfiqar A. Bhutta, André Briend, Sheila Isanaka, Tanya Khara, Natasha Lelijveld, Mark J. Manary, Andrew Mertens, Sophie E. Moore, Kieran S. O'Brien, Jonathan Wells, Priscah Lihanda, Eric Ochola, Grace Aldrovandi, Benson O. Singa, Christine J. McGrath   +17 more
wiley   +1 more source

Self-Initiation of Antiretroviral Therapy in the Developing World: the Involvement of Private Pharmacies in an HIV Program. [PDF]

, 2012
Self-initiation to antiretroviral treatment (ART) exposes the patient to the risk of drug toxicity, poor adherence to treatment, and escalates the development of drug resistance.
Buma, Deus, Minzi, Omary Mashiku, Kagashe GA, Buma, D., Minzi OM, Buma D, Kagashe, G.A., Kagashe, Godeliver A, Minzi, O.M.   +8 more
core   +1 more source

Effect of exposure to clinic-based health education interventions on behavioural intention to prevent mother-to-child transmission of HIV infection

SAHARA-J, 2006
HIV and AIDS incidence among infants in South Africa is on the increase. The uptake of prevention of mother-to-child transmission (PMTCT) interventions is often said to be dependent on the beliefs and educational needs of those requiring PMTCT services ...
Jude Igumbor, Supa Pengpid, Larry Obi
doaj   +1 more source