Results 71 to 80 of about 39,721 (242)

Outcomes of a remote, decentralized health center-based HIV/AIDS antiretroviral program in Zambia, 2003 to 2007 [PDF]

, 2009
A cross-sectional study of patients living with HIV/ AIDS treated during 2003 to 2007 in decentralized, rural health centers in Zambia was performed to measure virological outcomes after 12 months of antiretroviral therapy and identify factors associated
Elema, R, Mills, C, Yun, O, Lokuge, K, Ssonko, C, Nyirongo, N, Mtonga, V, Zulu, H, Tu, D, Verputten, M, O'Brien, D P   +10 more
core   +2 more sources

Effectiveness and safety of two‐drug regimens containing an integrase inhibitor and reverse transcriptase inhibitor in a cohort of virologically suppressed people with HIV: Data from the COMBINE‐2 study

HIV Medicine, Volume 27, Issue 4, Page 572-584, April 2026.
Abstract Objectives This study assessed real‐world effectiveness and safety of switching to dual therapy regimens consisting of an integrase inhibitor (INSTI), and reverse transcriptase inhibitor (RTI), among suppressed people living with HIV in Europe.
Cristina Mussini, Cassidy Henegar, Lambert Assoumou, Stephane de Wit, Margaret Johnson, Eugenia Quiros‐Roldan, Chris Kenyon, Colin Deschanvres, David Zucman, Frank Post, Roya Movahedi, Laura Comi, Julie Fox, Geoffrey Liegeon, Charlotte Martin, Jonathan Edwards, Giorgio Tiecco, Marc Delforge, Leigh Ragone, Bryn Jones, Jean van Wyk, Michael Aboud, Carl Fletcher, Anton Pozniak, Vani Vannappagari   +24 more
wiley   +1 more source

The impact of choice of NNRTI on short-term treatment outcomes among HIV-infected patients prescribed tenofovir and lamivudine in Johannesburg, South Africa. [PDF]

PLoS ONE, 2013
Recent WHO guidelines for resource-limited settings recommend tenofovir in first-line antiretroviral therapy (ART) yet there are suggestions that patients receiving nevirapine with tenofovir have worse outcomes than those receiving efavirenz.
Kate Shearer, Matthew P Fox, Mhairi Maskew, Rebecca Berhanu, Lawrence Long, Ian Sanne   +5 more
doaj   +1 more source

Steady-state pharmacokinetics of Nevirapine in HIV-1 infected adults in India [PDF]

, 2007
Background and Objectives: A variety of demographic factors, sex, and degree of immunosuppression can influence antiretroviral drug concentratians. The authors studied the influence of immune status, sex, and body mass index (BMI) on the steady-state ...
A.K. Hemanthkumar, C. Padmapriyadarsini, G. Narendran, Geetha Ramachandran, Hosseinipour MC, Kappelhoff BS, La Porte C., Phair JP, S. Anitha, S. Rajasekaran, Soumya Swaminathan, Sudha Subramanyam, V. Kumaraswami, World Health Organization.   +13 more
core   +1 more source

Trends and Patterns of Adverse Drug Reaction Reporting in Sierra Leone: A Retrospective Analysis of VigiFlow Data (2008–2022)

Pharmacoepidemiology and Drug Safety, Volume 35, Issue 3, March 2026.
ABSTRACT Purpose Adverse drug reactions (ADRs) present significant obstacles for healthcare systems, impacting both patient safety and the effectiveness of treatments. Despite this, there is a scarcity of research on ADR reports in Sierra Leone, especially over long periods.
Isatu Jalloh, Onome Thomas Abiri, Peter Bai James, Rajesh Vagiri, Neelaveni Padayachee   +4 more
wiley   +1 more source

Perbandingan Penggunaan Efavirenz dan Nevirapine Terhadap Kolesterol LDL Pasien HIV/AIDS

Pharmaceutical Sciences and Research, 2019
Gangguan metabolik lipid merupakan kondisi yang sering ditemukan pada pasien HIV (Human Immunodeficiency Virus)/AIDS (Acquired Immuno Deficiency Syndrome) pada pasien yang menggunakan antiretroviral (ARV) lini pertama seperti efavirenz dan nevirapine ...
Anggriani Yusi, Evy Yunihastuti, Yulia Trisna, Ade Rosanti, Reise Manninda, Rifka Annisa   +5 more
doaj   +1 more source

Analysis of prevalence of HIV-1 drug resistance in primary infections in the United Kingdom [PDF]

, 2001
Objectives: To identify changes since 1994 in the prevalence of resistance to anti-HIV drugs in primary HIV-1 infections in the United Kingdom. Design: Retrospective and prospective assessment of viruses obtained from people recently infected with HIV.
Baily, Guy, Cane, Patricia, Churchill, Duncan, Dean, Gill, Drake, Susan, Fisher, Martin, Pillay, Deenan, Porter, Kholoud   +7 more
core   +2 more sources

Comparative durability of nevirapine versus efavirenz in first-line regimens during the first year of initiating antiretroviral therapy among Swaziland HIV-infected adults

The Pan African Medical Journal, 2013
Nevirapine (NVP) and Efavirenz (EFV) have generally comparable clinical and virologic efficacy. However, data comparing NVP durability to EFV are imprecise.
Simbarashe Takuva, Denise Evans, Khangelani Zuma, Velephi Okello, Goedele Louwagie   +4 more
doaj   +1 more source

A Strategic Evaluation of Public Interest Litigation in South Africa [PDF]

, 2008
Based on three case studies, discusses trends and challenges in public interest litigations in South Africa, the most effective combination of strategies in advancing social change, and the role of litigation in social ...
Gilbert Marcus, Steven Budlender
core  

Recent Developments in HIV Antivirals: The Prospect of Prophylactic Drugs to Change the Pandemic

Microbial Biotechnology, Volume 19, Issue 2, February 2026.
Replication cycle of HIV‐1. The scheme provides an overview from virus entry over reverse transcription of viral RNA into viral DNA, provirus DNA integration into the host genome, genome expression by transcription and translation, proteolytic processing of the viral polyproteins, viral maturation to viral release from the cell. The various targets for
Harald Brüssow
wiley   +1 more source