Results 71 to 80 of about 19,421 (203)

Efavirenz challenge in patients with nevirapine induced Stevens-Johnson Syndrome

Southern African Journal of Infectious Diseases, 2016
Background: Non-nucleoside reverse transcriptase inhibitors (NNRTI) are recommended as part of first-line treatment by the World Health Organisation (WHO) for antiretroviral treatment (ART) naïve subjects.
Thandekile C. Manzini, Bernadett I. Gosnell, Melanie-Anne A. John, Mahomed Y. S. Moosa   +3 more
doaj   +1 more source

An Interactive Pharmacokinetic‐Pharmacodynamic Framework to Evaluate Bedaquiline Dose Modifications in Adults With Tuberculosis

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 5, May 2026.
ABSTRACT Bedaquiline is approved for use in a thrice‐weekly dosing schedule; simpler once‐daily dosing strategies could enable fixed‐dose combinations and improve patient adherence. We developed an interactive R Shiny simulation tool to enable the evaluation of different bedaquiline dosing schedules within an integrated dose‐pharmacokinetic‐efficacy ...
Yu‐Jou Lin, Frances Okibedi, Mats O. Karlsson, Elin M. Svensson   +3 more
wiley   +1 more source

Use of artemether-lumefantrine in the treatment of asymptomatic-malaria infection in HIV-positive and HIVnegative Nigerian adults. [PDF]

Malaria /HIV co-infection is a major challenge to public health in developing countries and yet potential drug-drug interactions between antimalarial and antiviral regimens have not been adequately investigated in people with both HIV and Plasmodium ...
Chijioke-Nwauche, IN
core   +1 more source

Long-term efficacy and safety of nevirapine-containing regimens in virologically suppressed patients: a 17-year follow up

HIV Research & Clinical Practice, 2019
Background: To evaluate long term outcomes in patients maintaining a NVP based regimen for more than 10 years. Materials and methods: Retrospective, multicenter, cohort study including virologically suppressed patients, currently receiving a NVP-based ...
Juan Tiraboschi, Natalia Lattour, Hernando Knobel, Pere Domingo, Esteve Ribera, Daniel Podzamczer   +5 more
doaj   +1 more source

International Normalized Ratio (INR) Increases amongst Two Patients Living with HIV on Warfarin after Being Switched from a Nevirapine to a Dolutegravir-Based Antiretroviral Regimen

Case Reports in Infectious Diseases, 2021
The increased use of dolutegravir-based regimens in the treatment of HIV is unmasking drug interactions, particularly in patients who were previously on nevirapine. Nevirapine is an enzyme inducer and increases the dosing requirements for cytochrome P450
Natalie Sang, Sonak Pastakia, Samuel Nyanje   +2 more
doaj   +1 more source

Tenofovir, Interferon Pathways, and Mucosal Immunity: Implications for People Living With HIV

American Journal of Reproductive Immunology, Volume 95, Issue 5, May 2026.
ABSTRACT Background Antiretroviral therapy (ART) suppresses HIV replication and protects people living with HIV (PLWH) from progressing to AIDS. However, despite ART, many PLWH experience chronic immune activation, which contributes to premature aging and non‐AIDS‐related comorbidities. One reason for this chronic immune activation (CIA) is HIV and its
Florian Hladik, Sean M. Hughes, Claire N. Levy, Rachel L. Creighton, Romel Mackelprang, Germán G. Gornalusse   +5 more
wiley   +1 more source

The operational effectiveness of a single dose Nevirapine prevention of mother to child transmission of HIV/AIDS programme in Khomas region, Namibia [PDF]

, 2010
Magister Public Health - MPHObjective: The study aim was to measure the operational effectiveness of a single dose Nevirapine for PMTCT programme among infants aged six weeks in Khomas region of Namibia.Methods: This was a retrospective record review ...
Siseho, Gloria Mutimbwa
core  

Should nevirapine be used to prevent mother-to-child transmission of HIV among women of unknown serostatus?

Bulletin of the World Health Organization
At present, HIV testing and counselling during pregnancy represent the key entry point for women to learn their serostatus and for them to access, if they are HIV-positive, specific interventions to reduce mother-to-child transmission (MTCT) of HIV ...
Tin Tin Sint, François Dabis, Claude Kamenga, Nathan Shaffer, Isabelle F. de Zoysa   +4 more
doaj   +1 more source

Possible hepatotoxic consequence of nevirapine use in juvenile albino rats [PDF]

Journal of Pharmacy & Pharmacognosy Research, 2017
Context: Nevirapine (NVP) is used in human immunodeficiency virus exposed neonates. This could present safety concern due to decreased liver metabolizing enzymes activity and renal clearance in neonates.
Elias Adikwu, Bonsome Bokolo
doaj  

A Review on Medicinal Chemistry and Biological Activity of Dihydropyrimidinones Against HIV

Archiv der Pharmazie, Volume 359, Issue 4, April 2026.
This article presents the latest advances in the development of dihydropyrimidinone (DHPM) derivatives as promising candidates against HIV. By exploring their interactions with essential viral targets and highlighting innovative compounds with potent antiviral activity, we provide an updated perspective on the opportunities for new antiretroviral ...
Debora I. Leite, Fernando B. Macedo, Murilo Marinho de C. Lima, Isabelle S. Brum, Jonathan Fragoso Miranda de Oliveira, Ana Clara S. Costa, Stella C. Duarte, Sarah Moon, Stefany de Castro B. Moura, Andressa P. de Oliveira, Nubia Boechat, Monica M. Bastos   +11 more
wiley   +1 more source