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Comparative effectiveness of dolutegravir + lamivudine versus three‐drug regimens in Swedish clinical practice: a nationwide study [PDF]

open access: yesJournal of the International AIDS Society
Introduction HIV guidelines recommend switching from a three‐drug regimen (3DR) to dolutegravir + lamivudine (DTG+3TC) for eligible individuals. This retrospective national cohort study used Swedish InfCareHIV registry data to evaluate long‐term outcomes
Erik Sörstedt   +9 more
doaj   +2 more sources

Clinical Trial of Lamivudine in Children with Chronic Hepatitis B [PDF]

open access: yesNew England Journal of Medicine, 2002
N Engl J Med. 2002 May 30;346(22):1706-13. Clinical trial of lamivudine in children with chronic hepatitis B. Jonas MM, Mizerski J, Badia IB, Areias JA, Schwarz KB, Little NR, Greensmith MJ, Gardner SD, Bell MS, Sokal EM; International Pediatric ...
Woynarowski Marek, Etienne M Sokal
exaly   +3 more sources

Suppression of HBV by Tenofovir in HBV/HIV coinfected patients : a systematic review and meta-analysis [PDF]

open access: yes, 2013
Background: Hepatitis B coinfection is common in HIV-positive individuals and as antiretroviral therapy has made death due to AIDS less common, hepatitis has become increasingly important. Several drugs are available to treat hepatitis B. The most potent
A Avihingsanon   +55 more
core   +24 more sources

Putative Repurposing of Lamivudine, a Nucleoside/Nucleotide Analogue and Antiretroviral to Improve the Outcome of Cancer and COVID-19 Patients

open access: yesFrontiers in Oncology, 2021
Lamivudine, also widely known as 3TC belongs to a family of nucleotide/nucleoside analogues of cytidine or cytosine that inhibits the Reverse Transcriptase (RT) of retroviruses such as HIV.
José J. García-Trejo   +2 more
doaj   +1 more source

Virological Response to Tenofovir Disoproxil Fumarate in HIV-Positive Patients with Lamivudine-Resistant Hepatitis B Virus Coinfection in an Area Hyperendemic for Hepatitis B Virus Infection. [PDF]

open access: yesPLoS ONE, 2016
Sequential addition of tenofovir disoproxil fumarate (TDF) is often needed for patients coinfected with HIV and hepatitis B virus (HBV) who develop HBV resistance to lamivudine after combination antiretroviral therapy (cART) containing only lamivudine ...
Yu-Shan Huang   +9 more
doaj   +1 more source

Removal of lamivudine from synthetic solution using jamun seed (Syzygium cumini) biochar adsorbent

open access: yesEmerging Contaminants, 2023
Antiviral drugs such as lamivudine have been globally identified in the environment and marked as emerging pollutants of concern due to their bioactive extremity.
Asha Ripanda   +7 more
doaj   +1 more source

Evaluation of the Activity of Lamivudine and Zidovudine against Ebola Virus. [PDF]

open access: yesPLoS ONE, 2016
In the fall of 2014, an international news agency reported that patients suffering from Ebola virus disease (EVD) in Liberia were treated successfully with lamivudine, an antiviral drug used to treat human immunodeficiency virus-1 and hepatitis B virus ...
Yu Cong   +35 more
doaj   +1 more source

Nano Co-Crystal Embedded Stimuli-Responsive Hydrogels: A Potential Approach to Treat HIV/AIDS

open access: yesPharmaceutics, 2021
Currently, the human immunodeficiency virus (HIV) that causes acquired immunodeficiency syndrome (AIDS) can only be treated successfully, using combination antiretroviral (ARV) therapy.
Bwalya A. Witika   +3 more
doaj   +1 more source

Dolutegravir plus lamivudine for maintenance of HIV viral suppression in adults with and without historical resistance to lamivudine: 48-week results of a non-randomized, pilot clinical trial (ART-PRO)

open access: yesEBioMedicine, 2020
: Background: We investigated the efficacy of a switch to dolutegravir plus lamivudine in aviremic individuals without evidence of persistent lamivudine resistance-associated mutations in baseline proviral DNA population sequencing. Methods: Open-label,
Rosa De Miguel   +21 more
doaj   +1 more source

DOLAVI Real-Life Study of Dolutegravir Plus Lamivudine in Naive HIV-1 Patients (48 Weeks)

open access: yesViruses, 2022
Brief: Real-world data in naïve HIV-1 patients demonstrate that dolutegravir plus lamivudine in a multiple tablet regimen is effective, safe, and satisfactory; it causes moderately increasing weight and abdominal circumference and is administrable on a ...
Carmen Hidalgo-Tenorio   +15 more
doaj   +1 more source

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