Results 31 to 40 of about 36,016 (212)

Management of Antiviral Resistance in Chronic Hepatitis B

open access: yesGut and Liver, 2017
The primary goal of therapy for chronic hepatitis B (CHB) is to prevent liver disease progression. Hepatitis B surface antigen (HBsAg) seroclearance or seroconversion is regarded as an optimal endpoint to discontinue treatment.
Young-Suk Lim
doaj   +1 more source

Treatment of subacute hepatitis B with lamivudine: A pilot study in Serbia [PDF]

open access: yesVojnosanitetski Pregled, 2009
Background/Aim. The incidence of acute hepatitis B viral (HBV) infection in adults has increased in recent years in Serbia. Most icteric patients with acute hepatitis B resolve their infection and do not require treatment.
Delić Dragan   +4 more
doaj   +1 more source

Update on rescue therapies in patients with lamivudine-resistant chronic hepatitis B [PDF]

open access: yes, 2013
Daniel C Chao, Ke-Qin HuDivision of Gastroenterology and Hepatology, University of California, Irvine Medical Center, Orange, CA, USAAbstract: Chronic hepatitis B continues to be a global problem, with an estimated 240 million cases according to the
Hu KQ   +3 more
core   +1 more source

Synthesis of (±)-Emtricitabine and (±)-Lamivudine by Chlorotrimethylsilane-Sodium Iodide Promoted Vorbrüggen Glycosylation

open access: yes, 2021
By simply adding water and sodium iodide (NaI) to chlorotrimethylsilane (TMSCl), promotion of a Vorbrüggen glycosylation en route to essential HIV drugs emtricitabine (FTC) and lamivudine (3TC) is achieved.
Timothy F., Jamison   +3 more
core   +1 more source

Successful lamivudine therapy for chronic hepatitis B in the family [PDF]

open access: yesVojnosanitetski Pregled, 2006
Background. Hepatitis B virus infection is a global public health problem since it is a leading cause of liver cirrhosis and hepatocellular carcinoma. An optimal treatment is needed to reduce mortality.
Nožić Darko
doaj   +1 more source

Green HPLC quantification method of lamivudine, zidovudine and nevirapine with identification of related substances in tablets

open access: yesGreen Chemistry Letters and Reviews, 2022
A green HPLC method for lamivudine (3TC), zidovudine (AZT) and nevirapine (NVP) determination in fixed-dose combination tablets was developed using ethanol as both one of the mobile phases and the solvent for sample preparation. This method was validated
Ludivine Vieira-Sellaï   +8 more
doaj   +1 more source

SDS‐CRISPR for Single‐Nucleotide Variant Detection

open access: yesAdvanced Science, EarlyView.
Structure‐disruption‐sensitive CRISPR (SDS‐CRISPR) converts structural instability into single‐nucleotide precision, thereby overcoming mismatch tolerance in canonical Cas12a and enabling versatile diagnostics across DNA, RNA, and microRNA targets. When applied to rapid IDH1 mutation detection for glioma genotyping and integrated with lateral‐flow ...
Xin Guan   +12 more
wiley   +1 more source

Clinical outcome of HBeAg-negative chronic hepatitis B in relation to virological response to lamivudine

open access: yes, 2004
The effect of lamivudine treatment on the outcome of patients with hepatitis B e antigen (HBeAg)-negative chronic hepatitis is unclear. In a retrospective multicenter study, we have analyzed the virological events observed during lamivudine therapy in ...
Almasio P. L.   +8 more
core   +1 more source

The Effects of Compulsory Licensing: A Case Study of HIV Drugs

open access: yesHealth Economics, EarlyView.
ABSTRACT Compulsory licensing is a legal mechanism that allows governments the use of patented medicines without the owner's consent, subject to conditions and compensation, to meet public‐health needs. Despite its policy relevance and increasing use, empirical evidence on its market effects remains limited.
Nicolau Martin‐Bassols   +2 more
wiley   +1 more source

PRETREATMENT WITH PEGYLATED INTERFERON PREVENTS EMERGENCE OF LAMIVUDINE MUTANTS IN LAMIVUDINE NAIVE PATIENTS

open access: yes, 2009
Background: In patients with advanced fibrosis, primary end points of long-term or possibly indefinite antiviral therapy are sustained inhibition of viral replication and avoidance of emergence of resistance. In lamivudine-treated patients, the strongest
CRITELLI R.   +4 more
core   +2 more sources

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