Results 11 to 20 of about 39,159 (175)

Rhabdomyolysis due to Lamivudine administration in acute viral hepatitis B infection: a case report from Malaysia

Electronic Physician, 2014
Rhabdomyolysis is a serious but rare side effect of Lamivudine treatment. Therefore, appropriate biochemical monitoring should be undertaken when it is used in the treatment of hepatitis B.
Janudin Baharin, Narisa Sulaiman Sahari, Sazlyna Mohd Sazlly Lim   +2 more
doaj   +2 more sources

Evaluating Vaginal Microbiome Effects on Antiretroviral Exposure in the Female Genital Tract Using Pharmacometric and Machine Learning Approaches [PDF]

Clinical Pharmacology &Therapeutics, EarlyView.
Antiretroviral pre‐exposure prophylaxis (PrEP) is less effective in women than expected, partly because drug exposure within the female genital tract is variable and may be influenced by the vaginal microbiome. We developed an integrated pharmacometrics and machine learning framework to evaluate associations between vaginal microbiome composition and ...
Diqin Yan, Lindsey B. Collins, Christopher Staley, Flavia Kiweewa Matovu, Pamala Jacobson, Melanie Nicol, Shen Cheng   +6 more
wiley   +2 more sources

QUANTITATION OF LAMIVUDINE BY UV SPECTROPHOTOMETRY [PDF]

Acta Biomedica Scientifica, 2017
HIV infection poses a threat to the existence of humankind as a whole. Currently, lamivudine is widely used in antiretroviral therapy regimens. Modern methods of assessing quality, both in substance and in tablets, are characterized by a number of ...
Y. A. Gonchikova, N. V. Chmelevskaya, E. A. Illarionova   +2 more
doaj   +2 more sources

Virologic, Lipid, Renal and Hepatic Laboratory Outcomes After Switching to Doravirine/Lamivudine/Tenofovir Disoproxil Fumarate in Treatment-Experienced People with HIV: Real-World Evidence from the SHINe-SHIC Cohort [PDF]

Infectious Disease Reports
Background/Objectives: Doravirine/lamivudine/tenofovir disoproxil fumarate (DOR/3TC/TDF) is used as a switch regimen in treatment-experienced people with HIV (PWH), particularly when simplification, lipid improvement, or avoidance of interaction-prone ...
Manuela Ceccarelli, Emmanuele Venanzi Rullo, Andrea Marino, Andrea De Vito, Cristina Micali, Serena Spampinato, Ylenia Russotto, Antonio Albanese, Maria Chiara Frasca, Sonia Agata Sofia, Giovanni Francesco Pellicanò, Benedetto Maurizio Celesia, Paolo Maggi, Giordano Madeddu, Giuseppe Nunnari   +14 more
doaj   +2 more sources

A prospective study of the evolution of lamivudine resistance mutations in patients with chronic hepatitis B treated with lamivudine [PDF]

, 2006
International audienceBackground/Aims. Lamivudine resistance has been described in subjects with chronic hepatitis B infections, associated with mutations in the viral polymerase gene.
Blin, Patrick, Poynard, Thierry, Landais, Paul, Degos, Françoise, Zoulim, Fabien, Al Hasnaoui, Abdelkhader, Slama, Alain, Deny, Paul, Trépo, Christian, Parvaz, Parviz, Mercier, Florence   +10 more
core   +7 more sources

Tracking the source of the hepatitis B virus-specific CD8 T cells during lamivudine treatment [PDF]

, 2003
Lamivudine treatment in chronic hepatitis B leads to the reconstitution of virus-specific T cells in the circulation, but it is not clear whether this is the preferential result of T cell efflux from the liver or lymph nodes.
Gotto, J, Williams, R, Webster, GJM, Dusheiko, GM, Bertoletti, A, Malacarne, F, Reignat, S, Behboudi, S, Burroughs, AK   +8 more
core   +2 more sources

Evolution of lamivudine resistance in human immunodeficiency virus type 1-infected individuals:the relative roles of drift and selection [PDF]

, 2000
Human immunodeficiency virus type 1 (HIV-1) rapidly develops resistance to lamivudine during monotherapy, typically resulting in the appearance at position 184 in reverse transcriptase (RT) of isoleucine instead of the wild-type methionine (M184I) early ...
Frost, SDW, Boucher, CAB, Leigh Brown, AJ, Nijhuis, M, Schuurman, R   +4 more
core   +1 more source

Suppression of HBV by Tenofovir in HBV/HIV Coinfected Patients: A Systematic Review and Meta-Analysis [PDF]

, 2013
Background: Hepatitis B coinfection is common in HIV-positive individuals and as antiretroviral therapy has made death due to AIDS less common, hepatitis has become increasingly important. Several drugs are available to treat hepatitis B. The most potent
Thomas Reiberger, Richard Gilson, Noriyoshi Kuzushita, Firouze Bani-Sadr (432319), Nüesch, R, David Dunn (37023), Marina Núñez, Lionel Tan, Stephan Christoph, Peters, M, Tan, L (Lionel), Pillay, Deenan, Huw Price, de Vries-Sluijs, T, Reto Nüesch, Dunn, David, Peters, Marion, Kuzushita, N, Kuzushita Noriyoshi, Firouze Bani-Sadr, Bani-Sadr, Firouze, Mauss Stefan, Reiberger, Thomas, Stefan Mauss, Gilson, Richard, Mamta K Jain, Theodora de Vries-Sluijs, Tan, Lionel, Gilson, R, Price, H, Gilson Richard, Huw Price (300124), Jain Mamta K., Peters Marion, Reiberger Thomas, Thomas Reiberger (143056), Nüesch Reto, Price, Huw, Richard Gilson (125405), David Dunn, Reto Nüesch (432324), Nüesch, Reto, Marina Núñez (432323), Pillay Deenan, Deenan Pillay (7888), Price Huw, Tan, L, Tan Lionel, Dunn David, Kuzushita, Noriyoshi, Christoph Stephan (283267), Stephan, C, Christoph Stephan, Pillay, D, Núñez Marina, Núñez, M, Stefan Mauss (143062), Bani-Sadr, F, Peters, M (Marjolein), Jain, MK, Bani-Sadr Firouze, de Vries-Sluijs Theodora, Stephan, Christoph, Theodora de Vries-Sluijs (432320), Lionel Tan (124548), Dunn, D, Marion Peters, Reiberger, T, Mamta K. Jain, Noriyoshi Kuzushita (432322), Mamta K. Jain (432321), Marion Peters (403490), Mauss, S, Jain, Mamta K., Núñez, Marina, Deenan Pillay, Nueesch, R, Peters, M.G. (Marion), Núñez, M.J. (Marina), Pillay, D. (Deenan), Nüesch, E. (Eveline), Tan, L. (Lionel), Price, H. (Huw), Mauss, S. (Stefan), Gilson, E. (Eric), Dunn, D. (David), Jain, A. (Ashok), Vriessluijs, T.E.M.S. (Theodora) de, Bani-Sadr, F. (Firouze), Stephan, C. (Carsten), Kuzushita, N. (Noriyoshi), Reiberger, T. (Thomas), de Vries-Sluijs, Theodora, Mauss, Stefan   +93 more
core   +1 more source

Long-term lamivudine treatment of children with chronic hepatitis B: durability of therapeutic responses and safety. [PDF]

, 2008
Lamivudine has been demonstrated safe and efficacious in the short term in a large cohort of children with chronic hepatitis B (CHB), but optimal duration of treatment has not been elucidated and limited data on the safety of long-term lamivudine ...
International Pediatric Lamivudine Investigator Group, Jonas, M, Little, N, Ferreira, G, Gardner, S   +4 more
core   +1 more source

Top-Down Synthesis of a Lamivudine-Zidovudine Nano Co-Crystal

Crystals, 2020
Lamivudine (3TC) and zidovudine (AZT) are antiretroviral agents used to manage HIV/AIDS infection. A wet media milling top-down approach was used to develop and produce nano co-crystals of 3TC and AZT.
Bwalya A. Witika, Vincent J. Smith, Roderick B. Walker   +2 more
doaj   +1 more source