Comparison of the Microwave-Heated Ziehl-Neelsen Stain and Conventional Ziehl-Neelsen Method in the Detection of Acid-Fast Bacilli in Lymph Node Biopsies. [PDF]
BACKGROUND: Tuberculosis is a chronic inflammatory disease with lymphadenopathy being the most common extra-pulmonary manifestation. The conventional Ziehl–Neelsen method plays an essential role in the diagnosis of tuberculosis; however, it has a low sensitivity in detecting acid-fast bacilli.
Ahmed GM +6 more
europepmc +6 more sources
A New Artificial Intelligence-Based Method for Identifying Mycobacterium Tuberculosis in Ziehl–Neelsen Stain on Tissue [PDF]
Mycobacteria identification is crucial to diagnose tuberculosis. Since the bacillus is very small, finding it in Ziehl–Neelsen (ZN)-stained slides is a long task requiring significant pathologist’s effort.
Sabina Zurac +2 more
exaly +3 more sources
Agreement between Direct Fluorescent Microscopy and Ziehl-Neelsen Concentration Techniques in Detection of Pulmonary Tuberculosis in Northwest Ethiopia. [PDF]
Background: The sensitivity of smear microscopy for diagnosis of tuberculosis might be improved through treatment of sputum with sodium hypochlorite and application of fluorescent microscopy.
Workineh M +7 more
europepmc +3 more sources
Improving the microbiological diagnosis of tuberculous meningitis: A prospective, international, multicentre comparison of conventional and modified Ziehl–Neelsen stain, GeneXpert, and culture of cerebrospinal fluid [PDF]
Highlights • Modified ZN staining of CSF with a cytospin step was not superior to conventional ZN staining for the diagnosis of TBM.• Modified ZN staining of CSF without a cytospin step was inferior to conventional ZN staining for the diagnosis of TBM ...
Dorothee Heemskerk +2 more
exaly +3 more sources
Introduction: Tuberculosis caused by Mycobacterium tuberculosis is a chronic infectious disease and a major health problem in developing countries, with lymphadenopathy being the most common presentation.
Krishna M, Gole SG.
europepmc +3 more sources
Comparative diagnostic utility of metagenomic next-generation sequencing, GeneXpert, modified Ziehl-Neelsen staining, and culture using cerebrospinal fluid for tuberculous meningitis: A multi-center, retrospective study in China. [PDF]
Early diagnosis of tuberculosis meningitis (TBM) remains a great challenge during clinical practice. The diagnostic efficacies of cerebrospinal fluid (CSF)‐based mycobacterial growth indicator tube (MGIT) culture, modified Ziehl–Neelsen (ZN) staining ...
Chen Y +13 more
europepmc +2 more sources
Ziehl-Neelsen stain in the pathology laboaratory: Performance and diagnostic aid for mycobacteria in bronchoalveolar lavage [PDF]
Introduction: With more than 100 years of use, the Ziehl-Neelsen stain is still currently used worldwide.Objective: To compare the performance of diagnostic tests used to determine mycobacteria in the clinic and pathology laboratory in bronchoalveolar ...
Arteta AA, Arias LF, Cadavid CE.
europepmc +2 more sources
Diagnostic performance of Ziehl-Neelsen staining and Auramine-Rhodamine staining techniques in the detection of pulmonary and extrapulmonary tuberculosis. [PDF]
Objective. To determine the diagnostic performance of Ziehl-Neelsen and Auramine-Rhodamine staining for pulmonary and extrapulmonary tuberculosis. Materials and methods. This was a cross-sectional diagnostic test study.
Tapia-Sequeiros G +8 more
europepmc +2 more sources
AI-Based Analysis of Ziehl-Neelsen-Stained Sputum Smears for Mycobacterium tuberculosis as a Screening Method for Active Tuberculosis. [PDF]
Tuberculosis is the primary cause of death due to infection in the world. Identification of Mycobacterium tuberculosis in sputum is a diagnostic test, which can be used in screening programs—especially in countries with a high incidence of tuberculosis ...
Witarto AB +22 more
europepmc +2 more sources
First detection of bovine tuberculosis by Ziehl-Neelsen staining and polymerase chain reaction at dairy farms in the Lekok Sub-District, Pasuruan Regency, and Surabaya region, Indonesia. [PDF]
Background and Aim: Bovine tuberculosis (TB) is a zoonotic disease of great public health importance, particularly in Indonesia, where control measures are limited or are not implemented. This study aimed to detect the presence of Mycobacterium pathogens
Desire IA +14 more
europepmc +2 more sources

