Results 181 to 190 of about 103,876 (310)

Silica Nanoparticles as Multifunctional Platforms for Vaccine Delivery and Immune Modulation in Infectious Diseases

open access: yesAdvanced NanoBiomed Research, Volume 5, Issue 12, December 2025.
Overview of the use of silica nanoparticles in vaccines against pathogens. Different kinds of vaccines against infectious diseases are currently using solid or mesoporous silica nanoparticles in their formulation. Silica microparticles and nanoparticles (SiNPs) have been studied as vehicles for vaccines.
Noe Juvenal Mendoza‐Ramírez   +3 more
wiley   +1 more source

Chemometric Methods Applied to Infrared and Raman Spectroscopy for Arboviruses Diagnosis: A Systematic Review With Meta‐Analysis

open access: yesAnalytical Science Advances, Volume 6, Issue 2, December 2025.
ABSTRACT Arboviruses such as dengue, Zika, chikungunya and yellow fever share similar clinical manifestations, making differential diagnosis challenging, particularly in endemic regions with viral co‐circulation. Conventional laboratory methods present important limitations, including cross‐reactivity and reliance on specialized infrastructure. In this
Karime Zeraik Abdalla Domingues   +5 more
wiley   +1 more source

Machine Learning–Driven Near‐ and Mid‐Infrared Chemometrics for Rapid, Cost‐Effective COVID‐19 Screening in Dried Plasma

open access: yesJournal of Chemometrics, Volume 39, Issue 12, December 2025.
ABSTRACT The COVID‐19 pandemic has highlighted the urgent need for rapid, accurate, and cost‐effective diagnostic alternatives to conventional methods such as RT‐qPCR and immunoassays. In this study, we explored the potential of vibrational spectroscopy, specifically near‐infrared (NIR) and mid‐infrared (MID) spectroscopy, for detecting SARS‐CoV‐2 ...
Fernanda F. S. Oliveira   +7 more
wiley   +1 more source

A human inferred germline antibody binds to an immunodominant epitope and neutralizes Zika virus

open access: gold, 2017
Diogo M. Magnani   +25 more
openalex   +2 more sources

Activation and Long‐Term Maintenance of Adaptive Immunity in the Central Nervous System: A Double‐Edged Sword?

open access: yesCNS Neuroscience &Therapeutics, Volume 31, Issue 12, December 2025.
A wide spectrum of cells in the brain can engage in antigen presentation, which activates adaptive immunity in the central nervous system (CNS). Tissue‐resident memory T cells (TRM) develop in adaptive immunity in the CNS and provide long‐term immune surveillance, including the clearance of pathogens and tumor cells.
Luojinyun Wang   +8 more
wiley   +1 more source

World Health Organization's Pathogen Access and Benefit‐Sharing system for digital sequence information and the Convention on Biological Diversity

open access: yesClinical and Translational Discovery, Volume 5, Issue 6, December 2025.
This article analyses the WHO Pandemic Agreement's Pathogen Access and Benefit‐Sharing system, highlighting unresolved challenges in digital sequence information governance and overlaps with the Convention on Biological Diversity, while offering recommendations for equitable, legally coherent implementation to enhance global pandemic preparedness ...
WooJung Jon
wiley   +1 more source

Impact of Zika Virus on adult human brain structure and functional organization [PDF]

open access: gold, 2018
Richard Bido‐Medina   +8 more
openalex   +1 more source

Advanced Electrochemical Genosensor for Zika Virus Detection in Biological Samples Based on Cysteamine‐Graphene Quantum Dots Bilayer

open access: yesElectroanalysis, Volume 37, Issue 12, December 2025.
An electrochemical biosensor for Zika virus (ZIKV) detection is described. A DNA probe was immobilized on a gold electrode. After hybridization with the target (ZIKV), safranin was used as an intercalating indicator. Detection was performed by differential pulse voltammetry (DPV), where the current signal increases with the target concentration.
Luiz F. G. Luz   +3 more
wiley   +1 more source

Connecting the Dots: Systems Thinking Highlights the Role of the Environment Sector in One Health Operationalization

open access: yesGlobal Challenges, Volume 9, Issue 12, December 2025.
This perspective highlights the need for a systems thinking approach in One Health to holistically address zoonotic disease prevention, and to strengthen connections with the environment sector for global pandemic preparedness. Abstract With One Health (OH) encompassing a holistic view of the interrelated health of humans, animals and environment ...
Alana Hansen   +3 more
wiley   +1 more source

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