Results 31 to 40 of about 41,582 (269)

Transforming RNA Degradation into Accurate RNA Detection: RNase I–Assisted Rolling Circle Amplification for Clinical Samples

Angewandte Chemie, EarlyView.
Here, we transform this otherwise destructive enzymatic activity into a powerful diagnostic advantage through an RNase I–assisted rolling circle amplification (RI‐RCA) strategy. By integrating controlled RNase I–mediated RNA digestion with circular DNA templates, this approach enables direct and highly sensitive detection of target RNA sequences. Using
Amal Mathai, Cheng‐Yu Lee, Zijie Zhang, Jimmy Gu, John D. Brennan, Yingfu Li   +5 more
wiley   +2 more sources

KNOWLEDGE AND PRACTICES OF MIDWIVES REGARDING ZIKA VIRUS IN KENDARI, SOUTHEAST SULAWESI, INDONESIA

Public Health of Indonesia, 2020
Background: In 2016 Zika virus infection became an international public health emergency concern. Objective: This study aimed to evaluate the knowledge and practice of midwives regarding the Zika virus.
Ramadhan Tosepu, Indri Eka Artamevia Khaerun Nisa Patawari, Hariati Lestari, Siti Rabbani Karimuna, La Ode Muhamad Sety, Fifi Nirmala   +5 more
doaj   +1 more source

Transmission of Zika virus by dendritic cell subsets in skin and vaginal mucosa

Frontiers in Immunology, 2023
Zika virus is a member of the Flaviviridae family that has caused recent outbreaks associated with neurological malformations. Transmission of Zika virus occurs primarily via mosquito bite but also via sexual contact. Dendritic cells (DCs) and Langerhans
Julia Eder, Julia Eder, Esther Zijlstra-Willems, Gerrit Koen, Neeltje A. Kootstra, Neeltje A. Kootstra, Katja C. Wolthers, Teunis B. Geijtenbeek, Teunis B. Geijtenbeek   +8 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Persistent Zika Virus Detection in Semen in a Traveler Returning to the United Kingdom from Brazil, 2016

Emerging Infectious Diseases, 2017
Zika virus is normally transmitted by mosquitos, but cases of sexual transmission have been reported. We describe a patient with symptomatic Zika virus infection in whom the virus was detected in semen for 92 days.
Katherine M. Gaskell, Catherine Houlihan, Eleni Nastouli, Anna M. Checkley   +3 more
doaj   +1 more source

Epidemiology of Zika Virus Infection [PDF]

The Journal of Infectious Diseases, 2017
Long known to be endemic in Africa and Southeast Asia and a rare cause of acute febrile illness, Zika virus (ZIKAV) arose from obscurity when an Asian genotype ZIKAV caused an outbreak of mild febrile illness in 2007 in Yap State, Federated States of Micronesia.
Susan L, Hills, Marc, Fischer, Lyle R, Petersen   +2 more
openaire   +2 more sources

Nano‐ and Micro‐Sized Solid Materials Used as Antiviral Agents

Advanced Functional Materials, EarlyView.
Due to the rise of viral infections in humans and possible viral outbreaks, the use of nano‐ or micro‐sized materials as antiviral agents is rapidly increasing. This review explores their antiviral properties against RNA and DNA viruses, either as a prevention or a treatment tool, by delving into their mechanisms of action and how to properly assess ...
Orfeas‐Evangelos Plastiras, Imelda Raczkiewicz, Peggy Bouquet, Jean‐Philippe Dacquin, Jeremy Dhainaut, Anne Goffard, Christophe Volkringer   +6 more
wiley   +1 more source

Zika virus disease

Saudi Journal of Medicine and Medical Sciences, 2017
The Zika virus is an arbovirus belonging to the virus family Flaviviridae. The virus was isolated in 1947 from a rhesus monkey in the Zika Forest of Uganda. The virus causes sporadic mild human infections in Africa and later in Asia.
Adel I Al-Afaleq
doaj   +1 more source

Membrane Fusion‐Inspired Nanomaterials: Emerging Strategies for Infectious Disease and Cancer Diagnostics

Advanced Healthcare Materials, EarlyView.
Membrane fusion‐inspired nanomaterials offer transformative potential in diagnostics by mimicking natural fusion processes to achieve highly sensitive and specific detection of disease biomarkers. This review highlights recent advancements in nanomaterial functionalization strategies, signal amplification systems, and stimuli‐responsive fusion designs,
Sojeong Lee, Khulan Nyamzaya, Jueun Han, Yejin Song, Jihee Lee, Jung Hyun Jo, Seungmin Bang, Eun‐Kyung Lim, Seungjoo Haam, Eunjung Kim   +9 more
wiley   +1 more source

ZIKA VIRUS: A REVIEW FROM THE VIRUS BASICS TO PROPOSED MANAGEMENT STRATEGIES

Mediterranean Journal of Hematology and Infectious Diseases, 2016
This review aims to summarize the body of knowledge available on Zika virus to date. A comprehensive review of the scientific literature on Zika virus was performed with the aim to stress relevant aspects for healthcare professionals in non-endemic area.
Lorenzo Zammarchi, Michele Spinicci, Michele Spinicci, Alessandro Bartoloni, Alessandro Bartoloni   +4 more
doaj   +1 more source