Results 61 to 70 of about 658,068 (316)

Zika virus infection induces host inflammatory responses by facilitating NLRP3 inflammasome assembly and interleukin-1β secretion

open access: yesNature Communications, 2018
Zika virus (ZIKV) infection is a public health emergency and host innate immunity is essential for the control of virus infection. The NLRP3 inflammasome plays a key role in host innate immune responses by activating caspase-1 to facilitate interleukin ...
Wenbiao Wang   +14 more
semanticscholar   +1 more source

Vaccination in a two-strain model with cross-immunity and antibody-dependent enhancement [PDF]

open access: yesarXiv, 2023
Dengue and Zika incidence data and the latest research have raised questions about how dengue vaccine strategies might be impacted by the emergence of Zika virus. Existing antibodies to one virus might temporarily protect or promote infection by the other through antibody-dependent enhancement (ADE).
arxiv  

Transmission of Zika virus by dendritic cell subsets in skin and vaginal mucosa

open access: yesFrontiers in Immunology, 2023
Zika virus is a member of the Flaviviridae family that has caused recent outbreaks associated with neurological malformations. Transmission of Zika virus occurs primarily via mosquito bite but also via sexual contact. Dendritic cells (DCs) and Langerhans
Julia Eder   +8 more
doaj   +1 more source

Birth Defects Among Fetuses and Infants of US Women With Evidence of Possible Zika Virus Infection During Pregnancy

open access: yesJournal of the American Medical Association (JAMA), 2017
Importance Understanding the risk of birth defects associated with Zika virus infection during pregnancy may help guide communication, prevention, and planning efforts.
M. Honein   +24 more
semanticscholar   +1 more source

Ensemble Forecasting of the Zika Space-TimeSpread with Topological Data Analysis [PDF]

open access: yesEnvironmetrics, 2020, 2020
As per the records of theWorld Health Organization, the first formally reported incidence of Zika virus occurred in Brazil in May 2015. The disease then rapidly spread to other countries in Americas and East Asia, affecting more than 1,000,000 people. Zika virus is primarily transmitted through bites of infected mosquitoes of the species Aedes (Aedes ...
arxiv  

Harnessing Nanohybridized Niclosamide for Precision Mpox Therapeutics

open access: yesAdvanced Healthcare Materials, EarlyView.
This study investigates the potential of nanohybridized niclosamide as a therapeutic agent for Mpox, focusing on enhanced bioavailability, improved antiviral efficacy, and controlled drug release achieved through nanoengineering. The research emphasizes significant advancements in formulation strategies, mechanistic insights, and therapeutic outcomes ...
N. Sanoj Rejinold   +2 more
wiley   +1 more source

Persistent Zika Virus Detection in Semen in a Traveler Returning to the United Kingdom from Brazil, 2016

open access: yesEmerging Infectious Diseases, 2017
Zika virus is normally transmitted by mosquitos, but cases of sexual transmission have been reported. We describe a patient with symptomatic Zika virus infection in whom the virus was detected in semen for 92 days.
Katherine M. Gaskell   +3 more
doaj   +1 more source

Mathematical modelling of the first HIV/ZIKV co-infection cases in Colombia and Brazil [PDF]

open access: yesarXiv, 2023
This paper presents a mathematical model to investigate co-infection with HIV/AIDS and zika virus (ZIKV) in Colombia and Brazil, where the first cases were reported in 2015-2016. The model considers the sexual transmission dynamics of both viruses and vector-host interactions.
arxiv  

Mathematical modeling of Zika disease in pregnant women and newborns with microcephaly in Brazil [PDF]

open access: yesMath. Methods Appl. Sci. 41 (2018), no. 18, 8929--8941, 2017
We propose a new mathematical model for the spread of Zika virus. Special attention is paid to the transmission of microcephaly. Numerical simulations show the accuracy of the model with respect to the Zika outbreak occurred in Brazil.
arxiv   +1 more source

Micro‐ and Nano‐Bots for Infection Control

open access: yesAdvanced Materials, EarlyView.
This review presents a strategic vision for integrating micro‐ and nanobots in the pipeline for infection diagnosis, prevention, and treatment. To develop these robots as a practical solution for infection management, their design principles are clarified based on their propulsion mechanisms and then categorized infection management domains based on ...
Azin Rashidy Ahmady   +5 more
wiley   +1 more source

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