Results 61 to 70 of about 41,582 (269)

The impacts of biological invasions

open access: yesBiological Reviews, EarlyView.
ABSTRACT The Anthropocene is characterised by a continuous human‐mediated reshuffling of the distributions of species globally. Both intentional and unintentional introductions have resulted in numerous species being translocated beyond their native ranges, often leading to their establishment and subsequent spread – a process referred to as biological
Phillip J. Haubrock   +42 more
wiley   +1 more source

Monodentate Phosphine Modulation in Cyclometallated Platinum(II) Complexes for Antileishmanial, Antiviral, and Antitumor Applications

open access: yesChemMedChem, EarlyView.
Schematic representation depicting the influence of phosphine ligand identity on the biological and physicochemical characteristics of Pt(II) complexes: PTA promotes antileishmanial activity, PPh2(Php–COOH) strengthens antiviral activity, and TCEP enhances fluorescence.
Antonio A. de Oliveira‐Neto   +12 more
wiley   +1 more source

Nervous System Injury and Neuroimaging of Zika Virus Infection

open access: yesFrontiers in Neurology, 2018
In 2016, World Health Organization announced Zika virus infection and its neurological sequalae are a public health emergency of global scope. Preliminary studies have confirmed a relationship between Zika virus infection and certain neurological ...
Shanshan Wu   +5 more
doaj   +1 more source

A clustered regularly interspaced palindromic repeat‐Cas12a‐based assay for rapid dengue virus monitoring in mosquito and clinical samples facilitating global collaborative surveillance and risk assessment to block dengue spreading

open access: yesInterdisciplinary Medicine, EarlyView.
The RAA‐Cas12a assay outperforms real‐time PCR in sensitivity (92.3%) while matching its specificity (100%) for dengue virus detection in clinical samples. It effectively identifies DENV in mosquitoes, with field data correlating to local outbreaks. This rapid, simple, and precise method serves as an early warning tool for dengue management.
Xiang Guo   +22 more
wiley   +1 more source

Serological evidence of Zika virus infection in febrile patients at Greater Accra Regional Hospital, Accra Ghana

open access: yesBMC Research Notes, 2019
Objective Increase in the evidence of global occurrence of Zika viral infection suggests that in Africa the circulation of the virus which causes 80% of asymptomatic infection could be undetected and/or overlooked.
Godson Aryee Ankrah   +4 more
doaj   +1 more source

Lymph‐based liquid biopsy: Current progress and future potential

open access: yesInterdisciplinary Medicine, EarlyView.
Recent evidence under the revised Starling principle indicates that lymph‐based liquid biopsies may offer superior diagnostic performance over blood‐based counterparts in certain clinical scenarios, such as early‐stage solid tumor detection. Currently, various biomarkers within the lymphatic system show significant diagnostic potential for a range of ...
Dongdong Liu   +6 more
wiley   +1 more source

Organoids and organ‐on‐a‐chip models for investigating the pathophysiology of the human reproductive system

open access: yesInterdisciplinary Medicine, EarlyView.
Organoids and organ‐on‐a‐chips are advancing reproductive system research. In the female reproductive system, applications include cancer organoid models, placental chips, and hormone simulation models. For the male reproductive system, research focuses on drug resistance mechanisms, co‐culture platforms, and infertility studies. These refined in vitro
Hongqi Zhang   +6 more
wiley   +1 more source

Zika Virus Infection and Implications for Reproduction

open access: yesFertility & Reproduction, 2019
Zika virus infection during pregnancy can have devastating effects on the foetus leading to congenital Zika syndrome. It is relevant therefore for couples living in countries with endemic Zika virus to understand the strategies they can utilise to reduce
Michelle L. Giles, Stephen Cole
doaj   +1 more source

Human Cyclophilins—An Emerging Class of Drug Targets

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova   +3 more
wiley   +1 more source

Projecting Month of Birth for At-Risk Infants after Zika Virus Disease Outbreaks

open access: yesEmerging Infectious Diseases, 2016
The marked increase in infants born with microcephaly in Brazil after a 2015 outbreak of Zika virus (Zika virus) disease suggests an association between maternal Zika virus infection and congenital microcephaly.
Jennita Reefhuis   +9 more
doaj   +1 more source

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