Results 11 to 20 of about 12,399 (131)

Efficacy of Different Combination Therapies for Mania in Bipolar Disorder: A Systematic Review and Meta-Analysis. [PDF]

Brain Behav
ABSTRACT Objective To systematically evaluate the efficacy and safety of different combination therapies in the treatment of mania in bipolar disorder, and to provide evidence‐based support for individualized clinical treatment. Methods PubMed, Web of Science, Cochrane Library, CNKI, VIP, and Wanfang databases were systematically searched from ...
Yao P, Ni P, Yin L.
europepmc   +2 more sources

Association of Atypical Antipsychotics With Lipid Abnormalities in Adult Patients With Schizophrenia: A Scoping Review. [PDF]

Neuropsychopharmacol Rep
This scoping review highlights the link between atypical antipsychotics and dyslipidaemia in adults with schizophrenia, identifying clozapine and olanzapine as high‐risk agents. Biomarkers and genetic polymorphisms offer promise for personalized treatment. Further research is needed on lesser‐studied drugs and predictive tools.
Abavana V, Sadiq S.
europepmc   +2 more sources

The Efficacy of Pharmacological Interventions in the Treatment of Major Depressive Disorder and Bipolar Depression With Mixed Features: A Systematic Review. [PDF]

Bipolar Disord
ABSTRACT Background There is a need to provide up‐to‐date, clinically translatable data as it relates to the treatment of a major depressive episode (MDE) with mixed features. Methods PubMed and OVID were searched from inception to July 22, 2024. Randomized controlled trials (RCTs) investigating the efficacy of pharmacological agents for adults with ...
Xiao N, Yin L, Lee S, Teopiz KM, Wong S, Le GH, Badulescu S, Lo HKY, Vinberg M, Cao B, Grande I, Rosenblat JD, McIntyre RS.   +12 more
europepmc   +2 more sources

Comparative Safety of Medications for Severe Agitation: A Geriatric Emergency Department Guidelines 2.0 Systematic Review. [PDF]

J Am Geriatr Soc
ABSTRACT Background Managing undifferentiated, severe agitation in older adults may require antipsychotic or sedative medications to prevent harm to self or others. Unfortunately, these medications are associated with serious adverse events in older adults, and little is known about their comparative safety.
Casey MF, Elder NM, Fenn A, Niznik J, Khoujah D, Cole JB, Cardon Z, Ding M, Goukasian N, Moreton E, Koehl JL, Magidson PD, Skains RM, Tyler K, Liu SW, Geriatric Emergency Department Guidelines Medication Safety Group.   +15 more
europepmc   +2 more sources

Pharmacotherapy of Psychotic Disorders in Türkiye: Insights From a National Prescription Database. [PDF]

Brain Behav
This 2019 national study evaluated antipsychotic prescriptions for patients ≥18 with schizophrenia or psychotic disorders across age, medication, region, and diagnosis. SGAs, especially quetiapine, were most prescribed, whereas sertindole, zuclopenthixol, haloperidol, chlorpromazine, and ziprasidone were least frequent.
Türkeş S, Kahve AC, Çin T, Yılmaz EŞ, Gürsöz H, Barun S.   +5 more
europepmc   +2 more sources

Ensuring generalizability and clinical utility in mental health care applications: Robust artificial intelligence-based treatment predictions in diverse psychosis populations. [PDF]

Psychiatry Clin Neurosci
Aim Artificial Intelligence (AI)‐based prediction models of treatment response promise to revolutionize psychiatric care by enabling personalized treatment, but very few have been thoroughly tested in different samples or compared to current clinical standards.
Coutts F, Mena S, Ucur E, Fleischhacker WW, Kahn R, Lieberman J, Hasan A, Howes O, Correll C, Koutsouleris N, Lalousis PA.   +10 more
europepmc   +2 more sources

Persistent akathisia masquerading as agitated depression after use of ziprasidone in the treatment of bipolar depression [PDF]

, 2013
There has been increasing recognition that the second-generation antipsychotic drugs can produce extrapyramidal side effects. This case reports the development of severe akathisia in a patient being treated with ziprasidone for bipolar depression.
Agarwal, Salina, Penders, Thomas M, Rohaidy, Rachel   +2 more
core   +1 more source

Costs in the Treatment of Schizophrenia in Adults Receiving Atypical Antipsychotics: An 11-Year Cohort in Brazil [PDF]

, 2018
Background: Schizophrenia is associated with significant economic burden. In Brazil, antipsychotics drugs, outpatient and hospital services are provided by the Brazilian National Health System for patients with schizophrenia.
Acurcio, Francisco de Assis, Barbosa, Wallace Breno, Barbui, Corrado, Bennie, Marion, Costa, Juliana de Oliveira, de Oliveira, Helian Nunes, Godman, Brian, Gomes, Rosangela Maria, Jr, Guerra Augusto Afonso, Pires de Lemos, Livia Lovato, Ruas, Cristina Mariano   +10 more
core   +2 more sources

Retrospective Study of Midazolam Protocol for Prehospital Behavioral Emergencies [PDF]

, 2020
Introduction: Agitated patients in the prehospital setting pose challenges for both patient care and emergency medical services (EMS) provider safety. Midazolam is frequently used to control agitation in the emergency department setting; however, limited
Huebinger, Ryan M., Markul, Eddie, Pearlman, Kenneth S., Richards, Christopher T., Stein-Spencer, Leslee, Tataris, Katie L., Weber, Joseph M., Zaidi, Hashim Q.   +7 more
core   +1 more source

Sexual dysfunction in first-episode schizophrenia patients: results from European First Episode Schizophrenia Trial [PDF]

, 2011
Sexual dysfunctions (SDs) occur frequently in schizophrenia patients and have a huge impact on quality of life and compliance. They are often associated with antipsychotic medication.
Fleischhacker, W. Wolfgang, Hummer, Martina, Kahn, René S., Kemmler, Georg, Malik, Peter, Riecher-Roessler, Anita   +5 more
core   +1 more source