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QTc Prolongation in Veterans With Heroin Dependence on Methadone Maintenance Treatment [PDF]

, 2015
Background: QTc prolongation and Torsade de Ppointes have been reported in patients on methadone maintenance. Objectives: In this study, QTc was compared before and after the veteran (n = 49) was on a stable dosage of methadone for 8.72 ± 4.50 years ...
Fernandez, Antony +3 more
core +2 more sources

THE COMORBIDITY OF BIPOLAR DISORDER AND CARDIOVASCULAR DISEASES FROM PHARMACOTHERAPY PERSPECTIVE [PDF]

, 2009
The heart and mind are intimately linked. Patients with severe mental disorders have increased mortality rates compared with the general population and the leading cause of premature death is cardiovascular disease (CVD).
Bjanka Vuksan–Ćusa +3 more
core +1 more source

NEW GENERATION VS. FIRST GENERATION ANTIPSYCHOTICS DEBATE: PRAGMATIC CLINICAL TRIALS AND PRACTICE-BASED EVIDENCE [PDF]

, 2009
There has been significant confusion about the relative advantage of new generation antipsychotics over first generation antipsychotics as well as of clinical trials performed to evaluate their efficacy vs. those designed to evaluate their effectiveness.
Miro Jakovljević
core +1 more source

PREGNANCY AND ATYPICAL ANTIPSYCHOTICS [PDF]

, 2009
Scientific research aiming at discovering new generations of effective medications is a common practice in medicine, and psychiatric research is no exception. Antipsychotics are used to treat chronic mental illnesses such as schizophrenia.
Daniela Petrić +4 more
core +1 more source

Delirium management in critically ill patients [PDF]

, 2013
Delirium among critically ill patients is common. Presence of delirium imparts a poorer prognosis to patients, including longer ICU and hospital length of stay, increased risk of institutionalization, higher health related costs, and elevated mortality ...
Calvo-Ayala, Enrique, Khan, Babar
core +1 more source

EJACULATORY DYSFUNCTION IN PATIENT WITH SCHIZOPHRENIA ON SERTINDOLE [PDF]

, 2010
The antipsychotic drugs can be of great benefit for the wide range of psychotic disorders, but all are associated with various adverse effects. Patients with psychotic disorder consider the sexual dysfunction to be among the most important side effects ...
Marija Kušan Jukić, Ninoslav Mimica, Stipe Drmić +2 more
core +1 more source

NICE DSU Technical Support Document 2: A Generalised Linear Modelling Framework for Pairwise and Network Meta-Analysis of Randomised Controlled Trials [PDF]