Comparison between ziv-aflibercept and ranibizumab for treatment of diabetic macular edema
Aim To evaluate safety and efficacy of ziv-aflibercept in comparison to ranibizumab for the treatment of diabetic macular edema (DME). Patients and methods A total of 84 patients (84 eyes) with DME and central macular thickness (CMT) greater than 350 μ ...
Abdalah S. Nasr +3 more
doaj +2 more sources
A phase Ib study of capecitabine and ziv-aflibercept followed by a phase II single-arm expansion cohort in chemotherapy refractory metastatic colorectal cancer [PDF]
Background Patients with chemotherapy refractory metastatic colorectal cancer (CRC) have a poor prognosis and limited therapeutic options. In this phase Ib/II clinical trial, we established the maximum tolerated dose (MTD) and recommended phase II dose ...
John H. Strickler +19 more
doaj +2 more sources
Ziv-aflibercept: a novel option for the treatment of polypoidal choroidal vasculopathy. [PDF]
Polypoidal choroidal vasculopathy (PCV) is an exudative maculopathy usually treated using photodynamic therapy (PDT) and antivascular endothelial growth factor agents. However, these cases may sometimes be refractory to both PDT and ranibizumab or bevacizumab, and may have persistent intra-retinal fluid. Recently, studies have reported that aflibercept
Videkar C +3 more
europepmc +6 more sources
Intravitreal Ziv-Aflibercept : Safety Analysis in Eyes Receiving More Than Ten Intravitreal Injections [PDF]
Purpose: To report the ocular and systemic adverse events in eyes receiving ≥10 intravitreal ziv-aflibercept (IVZ) injections. Methods: Medical records of patients who received ≥10 IVZ for various chorioretinal conditions with minimum follow up period of
Sumit Randhir Singh +2 more
exaly +3 more sources
Safety of 5914 intravitreal ziv-aflibercept injections [PDF]
Purpose To analyse the pooled safety data of intravitreal ziv-aflibercept (IVZ) therapy for various retinal conditions. Methods This was a retrospective, observational study which included patients from 14 participating centres who received IVZ.
Andrade, Gabriel Costa +21 more
core +3 more sources
Real-world treatment patterns and effectiveness among patients with metastatic colorectal cancer treated with ziv-aflibercept in community oncology practices in the USA [PDF]
Jasmina I Ivanova +2 more
exaly +2 more sources
Long-term outcome of treat and extend intravitreal ziv-aflibercept therapy [PDF]
Aim To assess the 30-month outcome of treat and extend (TAE) intravitreal ziv-aflibercept therapy in eyes with macular diseases. Methods In this prospective study, consecutive subjects received intravitreal 0.05 mL ziv-aflibercept (1.25 mg) injections ...
Charbaji, Abdulrazzak +4 more
core +3 more sources
A Phase II Study of FOLFIRI Plus Ziv-Aflibercept After Trifluridine/Tipiracil Plus Bevacizumab in Patients with Metastatic Colorectal Cancer: WJOG 11018G. [PDF]
Matsumoto T +21 more
europepmc +3 more sources

