Results 41 to 50 of about 895 (134)
Ziv-aflibercept in metastatic colorectal cancer. [PDF]
Biologics, 2014 The combination of cytotoxic chemotherapy and antiangiogenic agents has become a conventional treatment option for patients with metastatic colorectal cancer. Ziv-aflibercept is a fusion protein which acts as a decoy receptor for vascular endothelial growth factor (VEGF)-A, VEGF-B, and placental growth factor (PlGF); it was approved in combination with
Patel A, Sun W.
europepmc +6 more sources
Cancer Medicine, Volume 11, Issue 11, Page 2184-2192, June 2022., 2022 This multicenter retrospective study investigated whether a strategy of administering all available drugs leads to a better prognosis in metastatic colorectal cancer. Abstract Background The development of chemotherapy and treatment strategies for metastatic colorectal cancer (mCRC) have provided patients with significant survival benefits.
Takeshi Kawakami +13 more
wiley +1 more source
Thoracic Cancer, Volume 13, Issue 10, Page 1463-1470, May 2022., 2022 Anlotinib (AL3818), an oral, small‐molecular tyrosine kinase inhibitor, was approved as a first third‐ and further‐line treatment regime of relapsed SCLC in China in 2019. This study showed that the addition of anlotinib to standard etoposide/platinum chemotherapy achieved encouraging PFS and OS in previously untreated extensive‐stage small cell lung ...
Chang Liu +9 more
wiley +1 more source
Pharmacology Research &Perspectives, Volume 9, Issue 2, April 2021., 2021 Higher concentrations of anti‐VEGF agents have been observed after ocular administration of nanoparticulate systems in the long‐term in comparison to those of solution formulations of the same agents. The improvements on therapy offered by these nanoparticulate systems have also been evidenced in the higher antiangiogenic properties reported in in ...
María L. Formica +2 more
wiley +1 more source
Erratum to "Osteonecrosis of the jaw associated with ziv-aflibercept". [PDF]
J Gastrointest Oncol, 2017 europepmc +3 more sources
Clinical Case Reports, Volume 9, Issue 1, Page 61-66, January 2021., 2021 Association of immunotherapy and/or chemotherapy and/or targeted therapy, in sequence or as single therapies, may induce osteonecrosis of the jaw. Multidisciplinary team management of these patients should be provided. Abstract Association of immunotherapy and/or chemotherapy and/or targeted therapy, in sequence or as single therapies, may induce ...
Agostino Guida +4 more
wiley +1 more source
Intravitreal Therapy for Diabetic Macular Edema: An Update
Journal of Ophthalmology, Volume 2021, Issue 1, 2021., 2021 Diabetic macular edema (DME) represents a prevalent and disabling eye condition. Despite that DME represents a sight‐threatening condition, it is also among the most accessible to treatment. Many different treatment options including photocoagulation, intravitreal medical treatment (either vascular endothelial growth factor inhibitors or ...
Claudio Furino +4 more
wiley +1 more source
Drug Monographs: Ziv-aflibercept and Vincristine Sulfate Liposome [PDF]
Hospital Pharmacy, 2013 The complexity of cancer chemotherapy requires pharmacists be familiar with the complicated regimens and highly toxic agents used. This column reviews various issues related to preparation, dispensing, and administration of antineoplastic therapy, and the agents, both commercially available and investigational, used to treat malignant diseases.
Jessica N, Lee +2 more
openaire +2 more sources
pH of anti-VEGF agents in the human vitreous: low impact of very different formulations
International Journal of Retina and Vitreous, 2017 Background The aim of the study was to measure pH changes of the human vitreous caused by the intravitreal drugs bevacizumab, ranibizumab, aflibercept, and ziv-aflibercept.
Bianka Sobolewska +3 more
doaj +1 more source
Dll4 blockade potentiates the anti-tumor effects of VEGF inhibition in renal cell carcinoma patient-derived xenografts. [PDF]
PLoS ONE, 2014 The Notch ligand Delta-like 4 (Dll4) is highly expressed in vascular endothelium and has been shown to play a pivotal role in regulating tumor angiogenesis.
Kiersten Marie Miles +12 more
doaj +1 more source