Results 31 to 40 of about 744,309 (158)

The effects of gasotransmitters inhibition on homocysteine acutely induced changes in oxidative stress markers in rat plasma [PDF]

Scripta Medica, 2019
Background: The importance of homocysteine (Hcy) is increasingly recognized in last few decades as an independent risk factor for atherosclerosis and thrombosis, but there is lack of data referring to influence of Hcy on plasma oxidative stress ...
Đurić Marko, Kostić Sanja, Lončar-Stojiljković Dragana, Mutavdžin Slavica, Čolović Mirjana B., Krstić Danijela, Stevanović Predrag, Đurić Dragan M.   +7 more
doaj  

The Effect of Intracisternal Zn (II) Protoporphyrin IX on Vasospasm Process in the Experimental Subarachnoid Hemorrhage Model

, 2011
Background: Although there has been much work on it for years, cerebral vasospasm as a complication of subarachnoid bleeding is still an important cause of mortality and morbidity. The presented study was designed to examine the effects of heme oxygenase
Burcak Bilginer, Nejat Akalan, Narin, Firat, Isikay, Ilkay, AKALAN, NEJAT, Ilkay Isikay, Figen Soylemezoglu, BİLGİNER, BURÇAK, Firat Narin, Soylemezoglu, Figen   +9 more
core   +1 more source

Harnessing the nonthermal effects of ultrasound for cancer treatment: From mechanisms to applications

Smart Molecules, EarlyView.
Nonthermal ultrasound transforms acoustic energy into diverse therapeutic bioeffects through cavitation, mechanical stimulation, and physicochemical activation. This review discusses how acoustic parameters, biological mechanisms, and responsive materials interact to influence nonthermal ultrasound‐enabled cancer therapies. Mechanism‐guided engineering
Liu Wang, Huan Tang, Yue Pan, Mingle Li, Weijie Zhao, Kai Liu   +5 more
wiley   +1 more source

A Deep‐Red‐Absorbing Osmium(II) Complex as a Photosensitizer for Photodynamic Therapy Inducing Immunogenic Cell Death

Angewandte Chemie, Volume 138, Issue 27, 1 July 2026.
A deep‐red‐excited osmium(II) photosensitizer (Os2) induces immunogenic cell death (ICD) under 740 nm irradiation and triggers robust anti‐tumor immune responses both in vitro and in vivo. ABSTRACT Immunogenic cell death (ICD), which converts tumor cells into their own vaccine, plays a pivotal role in the development of novel anticancer therapies. Here,
Yiyi Zhang, Pierre Mesdom, Eduardo Izquierdo‐García, João P. M. António, Ruonan Gao, Bruno Saubaméa, Johanne Seguin, Morgane Moinard, Philippe Arnoux, Céline Frochot, Kevin Cariou, Bich‐Thuy Doan, Gilles Gasser   +12 more
wiley   +2 more sources

Smart mesoporous silica nanoparticles for precision cancer therapy: Tumor targeting and stimuli‐responsive controlled release

Smart Molecules, EarlyView.
Smart mesoporous silica nanoparticles integrate tunable pore structures, molecular gates, targeting ligands, and stimuli‐responsive components to achieve controlled drug release for precision cancer therapy. This review highlights design principles, therapeutic applications, and future directions in immunotherapy, biodegradability, biosafety, and ...
Majdi Al‐Amili, Lei Lei, Zhu Jin
wiley   +1 more source

Luminescence from protoporphyrin IX dimethyl ester

, 1975
Two excited states of protoporphyrin IX dimethyl ester have been identified using pulse radiolysis techniques.
McAuliffe, Charles A., Land, Edward J., Munn, Robert W., Chantrell, Susan J., Pratt, Albert C.   +4 more
core   +1 more source

A dual‐channel fluorescent probe for in situ imaging of mitochondrial superoxide and microenvironmental changes in Cd‐induced hepatorenal dysfunction

Smart Molecules, EarlyView.
A multi‐analyte‐responsive, dual‐emission fluorescent probe enables simultaneous imaging of viscosity/polarity and superoxide in the liver and kidneys. It reveals CdCl2‐induced hepatorenal ferroptosis through oxidative stress, mitochondrial dysfunction, and lipid peroxidation, providing a versatile platform for multi‐organ disease visualization ...
Zibo Zhai, Liang Tao, Jia Huang, Xijian Wang, Hailin Zhang, Yuandi Wang, Jiaoli Zhang, Dan Cheng, Longwei He, Songjiao Li   +9 more
wiley   +1 more source

Coproporphyrin-III from protoporphyrin-IX

, 1972
Manipulation of the vinyl side-chains of the readily available protoporphyrin-IX dimethyl ester (2) allows the synthesis of coproporphyrin-III tetramethyl ester (1) in an overall yield of 37%
Kenner, G. W., McCombie, S. W., Smith, K. M.   +2 more
core   +1 more source

Peptide‐directed nanovehicles enabling tumor‐selective ROS amplification and antitumor immunity

VIEW, EarlyView.
Cancer cells are vulnerable to oxidative stress, yet exploit immune tolerance to escape destruction. In contrast, their metabolic profile is markedly altered to support rapid proliferation, accompanied by elevated production of reactive oxygen species (ROS).
Manuela Calin, Galyna Bila, Ileana Manduteanu, Rostyslav Bilyy   +3 more
wiley   +1 more source

Characterisation of the flavin adenine dinucleotide binding region in Myxococcus xanthus protoporphyrinogen oxidase [PDF]

, 2011
This dissertation focuses on protoporphyrinogen oxidase (PPOX), the penultimate enzyme in the haem biosynthetic pathway. Partial defects in PPOX result in variegate porphyria, an autosomal dominant disorder.
Boateng, Mavis O
core   +1 more source