Severe resistant hypocalcemia in multiple myeloma after zoledronic acid administration: a case report [PDF]
, 2014 INTRODUCTION: Hypercalcemia is one of the most common metabolic abnormalities encountered in any form of malignancy. Hypocalcemia, however, is a rare manifestation, especially in cancers with bone involvement.
Adrian P Noriega Aldave, Shikha Jaiswal
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Oral Diseases, EarlyView.ABSTRACT Introduction Medication‐Related Osteonecrosis of the Jaw (MRONJ) is a severe adverse effect of antiresorptive and antiangiogenic treatment, primarily in osteoporotic and oncologic patients. The disease is characterized by persistent jawbone necrosis that results in significant impairment of the quality of life of involved patients.
Omar Ghanaiem +2 more
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Delayed alveolar bone repair and osteonecrosis associated with Zoledronic Acid therapy in rats: macroscopic, microscopic and molecular analysis [PDF]
, 2020 Gustavo Zanna Ferreira +5 more
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Navigating the evolving management of smoldering multiple myeloma
HemaSphere, Volume 10, Issue 1, January 2026.Abstract Smoldering multiple myeloma (SMM) represents an intermediate clinical stage between monoclonal gammopathy of undetermined significance (MGUS) and symptomatic multiple myeloma (MM). SMM carries a highly variable risk of progression to MM, requiring individualized risk stratification to guide management.
M. Bakri Hammami +6 more
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Compromised vertebral structural and mechanical properties associated with progressive kidney disease and the effects of traditional pharmacological interventions [PDF]
, 2015 BACKGROUND/AIMS: Patients with chronic kidney disease mineral and bone disorder (CKD-MBD) have a significantly higher vertebral and non-vertebral fracture risk than the general population.
Allen, Matthew R. +6 more
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Association between bisphosphonates and jaw osteonecrosis: a study in Wistar rats [PDF]
, 2011 BACKGROUND: This work aimed at determining whether bisphosphonate therapy produces a sufficient condition for jaw osteonecrosis after tooth extraction. METHODS: Rats were allocated into 3 groups: (1) 11 rats treated with alendronate, (2) 10 rats treated ...
Azambuja, Alan Arrieira +4 more
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Scientific Reports, 2019 Inhibiting osteoclasts and osteoclast precursors to reduce bone resorption is an important strategy to treat osteoclast-related diseases, such as peri-prosthetic osteolysis. In this study, our objective was to study the role of zoledronic acid (ZA), as a
Mei Li +5 more
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Usefulness of bone turnover markers as predictors of mortality risk, disease progression and skeletal-related events appearance in patients with prostate cancer with bone metastases following treatment with zoledronic acid: TUGAMO study [PDF]
, 2013 Owing to the limited validity of clinical data on the treatment of prostate cancer (PCa) and bone metastases, biochemical markers are a promising tool for predicting survival, disease progression and skeletal-related events (SREs) in these patients ...
Alcaraz, A. +42 more
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Остеопороз и остеопатии, 2013 Infusions of aminobisphosphonates are now established therapies ofpostmenopausal osteoporosis. Their use is associated with fever and musculoskeletal pain in some subjects, referred to as the acute phase response (APR).
O V Yakushevskaya, S V Yureneva
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Effect of systemically delivered zoledronic acid on joint damage, nociceptive knee innervation and pain after destabilization of the medial meniscus in mice [PDF]
, 2021 Alia M. Obeidat +3 more
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