Results 111 to 120 of about 5,114,489 (264)

Supplementary Figure 1 from Zoledronic Acid Has Differential Antitumor Activity in the Pre- and Postmenopausal Bone Microenvironment <i>In Vivo</i> [PDF]

open access: gold, 2023
Penelope D. Ottewell   +7 more
openalex   +1 more source

Physicians’ Preferences for Bone Metastases Drug Therapy in the United States [PDF]

open access: yes, 2015
ObjectiveSeveral characteristics of bone-targeted agents are considered when making treatment decisions. This study evaluated physicians’ therapy preferences for preventing skeletal-related events (SREs) in patients with bone metastases secondary to ...
Arellano, Jorge   +7 more
core   +1 more source

Pain Phenotype in Knee Osteoarthritis: Implications for Mechanism‐Based Therapy

open access: yesOrthopaedic Surgery, Volume 17, Issue 11, Page 3007-3021, November 2025.
The paper reported on the precise and individual treatment of knee osteoarthritis (KOA) pain based on its new classification, including Nociceptive Pain, Neuropathic Pain, and Nociplastic Pain. Tailored treatment recommendations for different types of pain through exploring potential mechanisms of pain in KOA are provided to achieve better clinical ...
Chenchang He   +5 more
wiley   +1 more source

Ovariectomy Stimulates and Bisphosphonates Inhibit Intracortical Remodeling in the Mouse Mandible [PDF]

open access: yes, 2010
Objective –  The pathophysiology of osteonecrosis of the jaw (ONJ) is thought to be linked to suppression of intracortical remodeling. The aim of this study was to determine whether mice, which normally do not undergo appreciable amounts of intracortical
Allen, Matthew R.   +2 more
core   +1 more source

Regulation of osteogenesis and osteoclastogenesis by zoledronic acid loaded on biodegradable magnesium-strontium alloy

open access: yesScientific Reports, 2019
Inhibiting osteoclasts and osteoclast precursors to reduce bone resorption is an important strategy to treat osteoclast-related diseases, such as peri-prosthetic osteolysis. In this study, our objective was to study the role of zoledronic acid (ZA), as a
Mei Li   +5 more
semanticscholar   +1 more source

Pediatric Scoliosis in Osteogenesis Imperfecta: From Genetic Mechanisms to Therapeutic Strategies

open access: yesOrthopaedic Surgery, Volume 17, Issue 11, Page 3036-3047, November 2025.
This review explores the genetic underpinnings and treatment strategies for spinal deformities in children with osteogenesis imperfecta. Emphasis is placed on emerging molecular insights and modern surgical techniques that improve the management of severe scoliosis and enhance patient outcomes.
Vladislav Muldiiarov   +2 more
wiley   +1 more source

Efficacy evaluation of denosumab in the treatment of patients with postmenopausal osteoporosis at high risk of fracture

open access: yesZhongguo Linchuang Yixue
ObjectiveTo explore the difference of efficacy and safety between denosumab and zoledronic acid in the treatment of patients with postmenopausal osteoporosis (PMOP), and to optimize the medication regimen for PMOP patients.
Jing ZHOU   +3 more
doaj   +1 more source

TREATMENT OF POSTMENOPAUSAL OSTEOPOROSIS WITH NITROGEN CONTAINING BISPHOSPHONATES, EARLY SIDE EFFECTS AND THEIR PREVENTION

open access: yesОстеопороз и остеопатии, 2013
Infusions of aminobisphosphonates are now established therapies ofpostmenopausal osteoporosis. Their use is associated with fever and musculoskeletal pain in some subjects, referred to as the acute phase response (APR).
O V Yakushevskaya, S V Yureneva
doaj   +1 more source

Corrigendum: A systematic review and economic evaluation of bisphosphonates for the prevention of fragility fractures [PDF]

open access: yes, 2016
Background Fragility fractures are fractures that result from mechanical forces that would not ordinarily result in fracture. Objectives To evaluate the clinical effectiveness and safety of bisphosphonates [alendronic acid (Fosamax® and Fosamax ...
Abrahamsen   +244 more
core   +2 more sources

Preoperative zoledronic acid therapy prevent hungry bone syndrome in patients with primary hyperparathyroidism

open access: yesIndian Journal of Endocrinology and Metabolism, 2017
Background: Hungry bone syndrome is a common complication of surgery for primary hyperparathyroidism in India which often leads to prolonged hospitalization. There are varying reports on the use and efficacy of bisphosphonates in the prevention of hungry
Sabaretnam Mayilvaganan   +2 more
doaj   +1 more source

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