Results 101 to 110 of about 2,744,211 (203)

Zoledrinic Acid Induces Steoblastic Differentiation of Mesenchymal Stem Cells without Change in Hypomethylation Status of OSTERIX Promoter [PDF]

Cell Journal, 2012
Objective: Mechanism of zoledronic acid on osteoblastic differentiation of mesenchymal stem cells (MSCs) has not fully understood. With the knowledge of some drugs mechanism that alter methylation pattern of some genes, the present research sets out to ...
Maryam Mahmodinia Maymand, Saeid Kaviani, Masoud Soleimani, Yousef Mortazavi, Mehrdad Noruzinia, Majid Farshdousti Hagh   +5 more
doaj  

Zoledronic Acid

Reactions Weekly, 2008
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Zoledronic acid in the management of metastatic bone disease

Therapeutics and Clinical Risk Management, 2008
Thomas J Polascik, Vladimir MouravievDuke Prostate Center and Division of Urologic Surgery, Duke University Medical Center, Durham, NC, USAAbstract: Many patients with advanced cancer experience decreased bone strength due to metastatic foci, underlying ...
Thomas J Polascik, Vladimir Mouraviev
doaj  

Spontaneously recovered severe thrombocytopaenia following zoledronic acid infusion for osteoporosis

, 2016
Zoledronic acid is widely used for the treatment of various skeletal disorders. While acute phase reactions are commonly seen, hypocalcaemia, femoral shaft fractures, osteonecrosis of the jaw and renal failure are rare.
Donthireddy, Vijayalakshmi, Rao, Sudhaker D, Kulkarni, Pooja, Cushman, Terra   +3 more
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Administered concentration-dependence (0.25–100 μM) of zoledronic acid fluxes (transport).

, 2015
(A) and intracellular zoledronic acid concentration (B). Zoledronic acid transport and intracellular accumulation was measured in confluent monolayers of primary human tubular cells using the steady state set-up. This figure represents the results of one
Anja Verhulst (700368), Charles E. McKenna (145054), Shuting Sun (700369), Patrick C. D’Haese (700370)   +3 more
core   +1 more source

Role of Denosumab and Zoledronic Acid in Geriatric Hip Fractures – A Comparative Analysis

Journal of Surgical Specialties and Rural Practice
Background: Osteoporotic hip fractures are on the raise in the world. Denosumab and zoledronic acid are among the commonly used current anti-osteoporotic medications to reduce hip fractures.
P Madhuchandra, S Nandeesh, K P Raju
doaj   +1 more source

Zoledronic acid and geranylgeraniol regulate cellular behaviour and angiogenic gene expression in human gingival fibroblasts

, 2014
The mevalonate pathway (MVP) and the anti-angiogenic effect of bisphosphonates have been shown to play a role in the pathogenesis of bisphosphonate-related osteonecrosis of the jaw (BRONJ).
Zafar, S., Seymour, G. J., Coates, D. E., Cullinan, M. P., Drummond, B. K., Milne, T.   +5 more
core   +1 more source

Orthodontic tooth movement and root resorption in ovariectomized rats treated by systemic administration of zoledronic acid [PDF]

Introduction: The effect of zoledronic acid, a potent and novel bisphosphonate, on tooth movement and orthodontically induced root resorption in osteoporotic animals systemically treated with zoledronic acid as similarly used in postmenopausal patients ...
Luppanapornlarp, Suwannee, Darendeliler, M. Ali, Yoshida, Noriaki, Gonzales, Carmen, Hotokezaka, Hitoshi, Hashimoto, Megumi, Sirisoontorn, Irin   +6 more
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Bisphosphonate (Zoledronic Acid) Associated Adverse Events: Single Center Experience

, 2010
Zoledronic acid is an efficacy-proven bisphosphonate used in the patients who develop bone metastasis. In our study, we planned to evaluate side effects occurring in the patients who receive zoledronic acid.
Uslu, Ruchan, Karabulut, Bulent, Gul, M. Kemal, Kucukzeybek, Yuksel, Gorumlu, Gurbuz, Cengiz, Ercument, Erten, Cigdem, Karaca, Burcak, Sanli, Ulus A.   +8 more
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KRAS-mutation status dependent effect of zoledronic acid in human non-small cell cancer preclinical models

, 2016
Background: In non-small cell lung cancer (NSCLC) KRAS-mutant status is a negative prognostic and predictive factor. Nitrogen-containing bisphosphonates inhibit prenylation of small G-proteins (e.g.
Cserepes, Mihály, Tóvári, József, Kói, Krisztina, Molnár, Dávid, Dobos, Judit, Horváth, Orsolya, Izsák, Vera, Hegedűs, Balázs, Tímár, József, Kenessey, István   +9 more
core   +1 more source