Results 81 to 90 of about 18,985 (204)

Quality of Life Assessment in Taiwanese Patients with Bone Metastases from Breast Cancer Receiving Zoledronic Acid

, 2014
Background: The current study aimed to examine the impact of zoledronic acid therapy on health-related quality of life (HRQoL) in Taiwanese patients with bone metastases from breast cancer.
Chao, Ta-Chung;Chen, Dar-Ren;Chao, Tsu-Yi;Chen, Shin-Cheh;Yeh, Dah-Cherng;Wang, Hwei-Chung;Huang, Wen-Tsung;Rau, Kun-Ming;Chang, King-Jen;Yang, Tsen-Long;Lee, Kuan-Der;Tai, Cheng-Jeng;Tseng, Ling-Ming;Hou, Ming-Feng, 張金堅   +1 more
core  

Incidence and Risk Factors of Serious Osteonecrosis in Pediatric Acute Lymphoblastic Leukemia: A CYP‐C Population‐Based Study

Pediatric Blood &Cancer, Volume 73, Issue 6, June 2026.
ABSTRACT Background Osteonecrosis (ON) is a debilitating complication of acute lymphoblastic leukemia (ALL) therapy. While numerous studies have explored its incidence and associated risk factors, investigations using large‐scale cohorts remain important to characterize ON across heterogeneous populations.
Noémie de Villiers, Chantal Éthier, Caroline Laverdière, Nathalie Alos, Thai Hoa Tran, Marie‐Claude Pelland‐Marcotte   +5 more
wiley   +1 more source

Oral delivery of zoledronic acid by non-covalent conjugation with lysine-deoxycholic acid

, 2022
S.1-10We assessed the possibility of changing the route of administration of zoledronic acid to an oral dosage form and its therapeutic efficacy in an estrogen-deficient osteoporosis rat model.
Kim, H.-S., Byun, Y., Jeon, O.-C., Park, J.W., Seo, D.-H.   +4 more
core   +1 more source

Genetic Bone Diseases: A Scoping Review of Pathology, Symptoms, Diagnosis, Treatment, and New Horizons

Advanced Genetics, Volume 7, Issue 2, June 2026.
This review highlights six genetic diseases of the bone, aiming to provide clinicians and researchers with updated information on their diagnosis and treatment. It also includes an assessment of common clinical and radiographic findings, along with pathophysiology related to diseases.
Colin Jones, Ambalangodage C. Jayasuriya
wiley   +1 more source

Zoledronic acid inhibits the growth of cancer stem cell derived from cervical cancer cell by attenuating their stemness phenotype and inducing apoptosis and cell cycle arrest through the Erk1/2 and Akt pathways

Journal of Experimental & Clinical Cancer Research, 2019
Background Zoledronic acid is the most potent osteoclast inhibitor and is widely used for advanced cancer patients with bone metastasis, but its role on cancer stem cells (CSCs) remains unclear.
Li Wang, Yanyang Liu, Yueling Zhou, Jiantao Wang, Li Tu, Zhen Sun, Xiujie Wang, Feng Luo   +7 more
doaj   +1 more source

Evaluation of the Effect of Zoledronic Acid Exposure on Nerve Cell in SH-SY5Y Neuroblastoma Cells

, 2022
Objective:Bisphosphonates are drugs that are effectively used for treating osteoporosis. Zoledronic acid (ZA) is a bisphosphonate type drug containing the imidazole group, used for treating osteoporosis.
Mehtap Kara
core   +1 more source

Biochemical bone biomarkers in plasma cell dyscrasias

British Journal of Haematology, Volume 208, Issue 6, Page 1909-1923, June 2026.
Visual abstract depicting that bone turnover markers reflect dynamic alterations in bone remodelling across the spectrum of plasma cell dyscrasias but remain limited by assay variability, biological confounding and incomplete integration with imaging and risk stratification.
Guido Nador, Rohit Vijjhalwar, Muhammad Kassim Javaid, Claire M. Edwards, Karthik Ramasamy   +4 more
wiley   +1 more source

Renal safety of annual zoledronic acid infusions in osteoporotic postmenopausal women

, 2008
Intravenous bisphosphonates reduce fracture risk but have been associated in rare cases with deteriorating renal-function in cancer patients. The renal effects of zoledronic acid were assessed in osteoporotic postmenopausal women from 27 countries who ...
Abrams, Ken, Mesenbrink, Peter, Eriksen, Erik F, Miller, Paul D., Sellmeyer, Deborah E, Eriksen, Erik F., Miller, Paul D, Orlov-Morozov, Alexander, Sellmeyer, Deborah E., Boonen, Steven, Lippuner, Kurt   +10 more
core   +1 more source

Mevalonates restore zoledronic acid-induced osteoclastogenesis inhibition. [PDF]

, 2015
福岡歯科大学博士（歯学）2014年度Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is likely to be caused by continuous imperfection of bone healing after surgical treatments in patients with long-term administration of nitrogen-containing bisphosphonates (NBPs).
Okabe, Koji, Ozeki, Satoru, Kajiya, Hiroshi, Nagaoka, Yoshiyuki, Ikebe, Tetsuro   +4 more
core   +1 more source

Efficacy evaluation of denosumab in the treatment of patients with postmenopausal osteoporosis at high risk of fracture

Zhongguo Linchuang Yixue
ObjectiveTo explore the difference of efficacy and safety between denosumab and zoledronic acid in the treatment of patients with postmenopausal osteoporosis (PMOP), and to optimize the medication regimen for PMOP patients.
Jing ZHOU, Xingyun HOU, Tingting LIU, Jiaoyang ZHENG   +3 more
doaj   +1 more source