Results 61 to 70 of about 18,985 (204)
Breast-cancer adjuvant therapy with zoledronic acid [PDF]
BACKGROUND Data suggest that the adjuvant use of bisphosphonates reduces rates of recurrence and death in patients with early-stage breast cancer. We conducted a study to determine whether treatment with zoledronic acid, in addition to standard adjuvant ...
Peterson, Jennifer +19 more
core +3 more sources
Study of Adverse Effect Profile of Parenteral Zoledronic Acid in Female Patients with Osteoporosis [PDF]
Introduction: Osteoporosis is still a under recognized entity in the population. Osteoporosis-related fractures can be prevented if people at risk can be screened, diagnosed and treated early.
Prem Kotian +2 more
doaj +1 more source
Alterations of bone proteins in medication‐related osteonecrosis of the jaw
Abstract Changes in the protein expression pattern of osteoblastic lineage cells from the alveolar bone (OLAB) during medication‐related osteonecrosis of the jaw (MRONJ) have rarely been investigated. This lack of information is partly because of the limited availability of healthy samples and the lack of human alveolar bone cell lines for research ...
Andrea Schubert +6 more
wiley +1 more source
Objective: The primary purpose of this study was to estimate the cost-effectiveness of sequential denosumab/zoledronic acid versus zoledronic acid monotherapy for postmenopausal osteoporotic women in China.Methods: We updated and utilized a previously ...
Lei Ke (217815) +6 more
core +1 more source
Osteoporosis and Periodontitis: Two‐Way Epidemiological and Mechanistic Evidence
This review investigates the main mechanistic pathways connecting local periodontitis to systemic osteoporosis. Seven interconnected mechanisms are identified. ABSTRACT Osteoporosis and periodontitis are highly prevalent, chronic inflammatory diseases that constitute a major global health burden.
Jia Chang +3 more
wiley +1 more source
Once-yearly zoledronic acid in hip fracture prevention
Oddom Demontiero, Gustavo DuqueAging Bone Research Program, Nepean Clinical School, University of Sydney, Penrith, NSW, Australia; Department of Geriatric Medicine, Nepean Hospital, Penrith, NSW, AustraliaAbstract: Osteoporosis is an escalating global ...
Demontiero, O +4 more
core +1 more source
ObjectiveWe aimed to assess the cost-effectiveness of sequential teriparatide/zoledronic acid relative to zoledronic acid monotherapy for postmenopausal osteoporotic women in China.MethodsA previously validated Markov microsimulation model was updated to
Lei Ke (217815) +5 more
core +1 more source
Zoledronic acid, a highly potent nitrogen-containing bisphosphonate used for the treatment of pathological bone loss, is excreted unmetabolized via the kidney if not bound to the bone.
Anja Verhulst +3 more
doaj +1 more source
ABSTRACT Introduction Medication‐Related Osteonecrosis of the Jaw (MRONJ) is a severe adverse effect of antiresorptive and antiangiogenic treatment, primarily in osteoporotic and oncologic patients. The disease is characterized by persistent jawbone necrosis that results in significant impairment of the quality of life of involved patients.
Omar Ghanaiem +2 more
wiley +1 more source
ObjectiveWe aimed to assess the cost-effectiveness of sequential teriparatide/zoledronic acid relative to zoledronic acid monotherapy for postmenopausal osteoporotic women in China.MethodsA previously validated Markov microsimulation model was updated to
Lei Ke (217815) +5 more
core +1 more source

