Results 61 to 70 of about 5,946,067 (288)
Comparison of osteoporosis pharmacotherapy fracture rates: Analysis of a marketScan® claims database cohort [PDF]
, 2018 Background: Several different classes of medications have been shown to be efficacious at preventing fractures in patients with osteoporosis. No study has compared real world efficacy at preventing fractures between all currently approved medications ...
Fox, Edward J. +5 more
core +2 more sources
Journal of the American Medical Association (JAMA), 2020 Importance A proof-of-principle study suggested that intravenous zoledronic acid may reduce knee pain and the size of bone marrow lesions in people with knee osteoarthritis, but data from large trials are lacking.
G. Cai +13 more
semanticscholar +1 more source
Association between bisphosphonates and jaw osteonecrosis: a study in Wistar rats [PDF]
, 2011 BACKGROUND: This work aimed at determining whether bisphosphonate therapy produces a sufficient condition for jaw osteonecrosis after tooth extraction. METHODS: Rats were allocated into 3 groups: (1) 11 rats treated with alendronate, (2) 10 rats treated ...
Azambuja, Alan Arrieira +4 more
core +1 more source
Various pathways of zoledronic acid against osteoclasts and bone cancer metastasis: a brief review
BMC Cancer, 2020 Zoledronic acid (ZA) is one of the most important and effective class of anti-resorptive drug available among bisphosphonate (BP), which could effectively reduce the risk of skeletal-related events, and lead to a treatment paradigm for patients with ...
Lianwei Wang +3 more
semanticscholar +1 more source
Assessment of the Impact of Zoledronic Acid on Ovariectomized Osteoporosis Model Using Micro-CT Scanning. [PDF]
PLoS ONE, 2015 Prompted by preliminary findings, this study was conducted to investigate the impact of zoledronic acid on the cancellous bone microstructure and its effect on the level of β-catenin in a mouse model of postmenopausal osteoporosis.96 8-week-old specific ...
Bo Shuai +5 more
doaj +1 more source
Does industry-sponsored education foster overdiagnosis and overtreatment of depression, osteoporosis and over-active bladder syndrome? An Australian cohort study [PDF]
, 2018 ObjectivesTo investigate patterns of industry-sponsored educational events that focus on specific health conditions for which there are concerns about overdiagnosis and overtreatment.Design and settingThis retrospective cohort study examines publicly ...
Bero, Lisa +5 more
core +1 more source
Science Advances, 2020 Combining BMP-2 and zoledronic acid is a recipe for creating “synthetic autologous bone” to treat large bone defects. Bone morphogenic proteins (BMPs) are the only true osteoinductive molecules.
D. Raina +7 more
semanticscholar +1 more source
Dosing of zoledronic acid with its anti-tumor effects in breast cancer
Journal of Bone Oncology, 2015 Bisphosphonates have played an important role in the treatment of breast cancer, mainly in patients with bone metastasis, by reducing the risk of fracture, spinal cord compression, and hypercalcemia.
Xinmin Zhao, Xichun Hu
doaj +1 more source
synergistic cytoreductive effects of zoledronic acid and radiation on breast cancer cells [PDF]
, 2006 Introduction Bisphosphonates are mostly used in the treatment of bone metastases. They have been shown to act synergistically with other chemotherapeutic agents. It is not known, however, whether similar synergistic effects exist with radiation on breast
A Ugur Ural +30 more
core +1 more source
Prostate Cancer, 2011 Background. Loss of bone density with androgen deprivation therapy for prostate cancer is well recognized. We assessed the effects of quarterly infusion of zoledronic acid on bone mineral density (BMD) and markers of bone turnover over a one-year period ...
Anoop Kapoor +3 more
doaj +1 more source