Current perspectives on skeletal health and cancer progression across the disease continuum in breast cancer—The role of bisphosphonates [PDF]
, 2012 Pre-clinical and clinical evidence suggest that bisphosphonates inhibit both bone resorption and cancer progression. New and updated analyses from several large, controlled studies in pre- and post-menopausal women with early stage breast cancer (BC ...
Aft, R.
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Zoledronic acid affects the process of Porphyromonas gingivalis infecting oral mucosal epithelial barrier: An in-vivo and in-vitro study [PDF]
, 2023 Hanyu Sun +4 more
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Zoledronic acid exacerbates inflammation through M1 macrophage polarization
Inflammation and Regeneration, 2018 Zoledronic acid (Zol), one of the bisphosphonates, is frequently utilized for the treatment of osteoporosis and bone metastasis. However, the onset of medication-related osteonecrosis of the jaw (MRONJ) following dental treatments has become a serious ...
Junya Kaneko +7 more
semanticscholar +1 more source
Case Reports in Oncology, 2012 Zoledronic acid suppresses osteoclastic changes and reduces the risk of cancer-induced skeletal-related events. Moreover, it has been reported to have antitumor effects.
Sadayuki Kawai +3 more
doaj +1 more source
Erratum to: Pain and health-related quality of life in patients with advanced solid tumours and bone metastases: integrated results from three randomized, double-blind studies of denosumab and zoledronic acid [PDF]
, 2014 Roger von Moos +13 more
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Acute Iridocyclitis Associated With Intravenous Zoledronic Acid: A Case Report [PDF]
, 2023 Anvitha Ankireddypalli +1 more
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Bisphosphonates for post-menopausal osteoporosis: are they all the same? [PDF]
, 2017 The primary goal of treatment for post-menopausal osteoporosis (PMO) is reduction in fracture risk. Therefore, clinicians must recommend therapies that are safe and have proven anti-fracture efficacy.
Rizzoli, R.
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Compromised vertebral structural and mechanical properties associated with progressive kidney disease and the effects of traditional pharmacological interventions [PDF]
, 2015 BACKGROUND/AIMS: Patients with chronic kidney disease mineral and bone disorder (CKD-MBD) have a significantly higher vertebral and non-vertebral fracture risk than the general population.
Allen, Matthew R. +6 more
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Pain Physician, 2019 OBJECTIVE To investigate the therapeutic effectiveness of percutaneous kyphoplasty (PKP) combined with zoledronic acid in treatment of primary osteoporotic vertebral compression fractures.
Zi-Feng Huang +3 more
semanticscholar +1 more source
High Serum Concentration of Interleukine-6 and Rank-ligand as Risk Factors for Osteoporosis in Estrogen Deficiency Post-menopausal Women [PDF]
, 2009 Osteoporosis in post-menopausal women is not merely due to deficient estrogenhormone production. The development of osteoporosis is due to increased boneresorption by osteoclasts. The osteoclast\u27s number and activity is controlled by activatingfactors
Bakta, M. (Made) +3 more
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