Results 21 to 30 of about 22,649 (238)
Life-threatening hyperkalemia following zoledronic acid infusion for Paget's disease: a case report
Journal of Medical Case Reports, 2011 Introduction Zoledronic acid is a highly effective treatment in Paget's disease for persistent bone pain and prevention of further progression of the disease. The commonest electrolyte abnormality is hypocalcemia. To the best of our knowledge this is the
Naysmith Morag +2 more
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Current Therapeutic Research, 2021 : Background: Several studies have investigated the immunomodulating properties of zoledronic acid on T lymphocytes, but the causal relationship between the function of T cells and the efficacy of zoledronic acid has not been elucidated Objective: To ...
Min Cui, Ph. D +4 more
doaj
Zoledronic acid and atorvastatin inhibit αvβ3-mediated adhesion of breast cancer cells
Journal of Bone Oncology, 2014 Bone metastases represent common long term complications of patients with breast cancer. Zoledronic acid, an amino-bisphosphonate and mevalonate pathway inhibitor, is an established agent for the treatment of bone metastases.
Maria Wilke +8 more
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Activation of BK(Ca) channels in zoledronic acid-induced apoptosis of MDA-MB-231 breast cancer cells. [PDF]
PLoS ONE, 2012 BACKGROUND: Zoledronic acid, one of the most potent nitrogen-containing biphosphonates, has been demonstrated to have direct anti-tumor and anti-metastatic properties in breast cancer in vitro and in vivo.
Yu-Guang Ma +10 more
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Interaction of solid organic acids with carbon nanotube field effect transistors [PDF]
Chem. Phys. Lett. 430 (2006) 75, 2007 A series of solid organic acids were used to p-dope carbon nanotubes. The extent of doping is shown to be dependent on the pKa value of the acids. Highly fluorinated carboxylic acids and sulfonic acids are very effective in shifting the threshold voltage and making carbon nanotube field effect transistors to be more p-type devices.
arxiv +1 more source
The anti-tumour effects of zoledronic acid
Journal of Bone Oncology, 2014 Bone is the most common site for metastasis in patients with solid tumours. Bisphosphonates are an effective treatment for preventing skeletal related events and preserving quality of life in these patients. Zoledronic acid (ZA) is the most potent osteoclast inhibitor and is licensed for the treatment of bone metastases.
Maged Mansour +2 more
openaire +4 more sources
Dosing of zoledronic acid with its anti-tumor effects in breast cancer
Journal of Bone Oncology, 2015 Bisphosphonates have played an important role in the treatment of breast cancer, mainly in patients with bone metastasis, by reducing the risk of fracture, spinal cord compression, and hypercalcemia.
Xinmin Zhao, Xichun Hu
doaj +1 more source
Prostate Cancer, 2011 Background. Loss of bone density with androgen deprivation therapy for prostate cancer is well recognized. We assessed the effects of quarterly infusion of zoledronic acid on bone mineral density (BMD) and markers of bone turnover over a one-year period ...
Anoop Kapoor +3 more
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BMC Musculoskeletal Disorders, 2021 Background Revisions are mainly caused by wear debris-induced aseptic loosening. How to effectively suppress debris-induced periprosthetic osteolysis has become an urgent problem.
Peng Wang +5 more
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Ab initio design of drug carriers for zoledronate guest molecule using phosphonated and sulfonated calix[4]arene and calix[4]resorcinarene host molecules [PDF]
, 2017 Monomolecular drug carriers based on calix[n]-arenes and -resorcinarenes containing the interior cavity can enhance the affinity and specificity of the osteoporosis inhibitor drug zoledronate (ZOD). In this work we investigate the suitability of nine different calix[4]-arenes and -resorcinarenes based macrocycles as hosts for the ZOD guest molecule by ...
arxiv +1 more source