Results 51 to 60 of about 4,939 (180)

Zollinger-Ellison syndrome: a case report

Zdravniški Vestnik, 2006
Background: Zollinger-Ellison syndrome is the consequence of excessive and autonomous secretion of gastrin from gastrinoma cells. The disease is exceptionally rare and characterized by severe and treatment-resistant peptic disease that can become life ...
Mitja Krajnc, Miro Čokolič
doaj  

Somatostatin receptor molecular imaging in a misdiagnosed gastrinoma case

World Journal of Nuclear Medicine, 2020
Gastrin-secreting tumors, hypergastrinemia and severe ulcer disease form the trademarks of Zollinger-Ellison syndrome (ZES). We report a case of gastrinoma, in a patient who was misdiagnosed for almost five years.
Cati Stolniceanu, Irena Grierosu, Milovan Matovic, Cipriana Stefanescu   +3 more
doaj   +1 more source

Peptic ulcer: the current state of the problem

Медицинский совет, 2022
Peptic ulcer disease (PUD) is a chronic polyetiological recurrent disease of gastroduodenal region. In most cases, the pathogenesis of PU is caused by imbalance between the aggressive factors and protective factors of the gastric or duodenal mucosa ...
I. V. Maev, D. N. Andreev, A. A. Samsonov, A. S. Cheryomushkina   +3 more
doaj   +1 more source

Cholecystokinin: Clinical aspects of the new biology

Journal of Internal Medicine, Volume 298, Issue 3, Page 251-267, September 2025.
Abstract Cholecystokinin (CCK) is a classic gut hormone that has been known for almost a century to regulate gallbladder emptying, pancreatic enzyme secretion, and gastrointestinal motor activity. In 1968, the CCK structure was identified by Viktor Mutt and Erik Jorpes from porcine gut extracts as a peptide of 33 amino acid residues.
Jens F. Rehfeld
wiley   +1 more source

Esomeprazole Potentiates the Cytotoxic Effects of Cisplatin in Gastric Carcinoma Cells

Journal of Biochemical and Molecular Toxicology, Volume 39, Issue 8, August 2025.
Esomeprazole potentiates cisplatin‐induced cytotoxicity in SNU‐1 gastric cancer cells by enhancing oxidative stress, apoptosis, mitochondrial dysfunction, and DNA damage. ABSTRACT Proton pump inhibitors (PPIs), including esomeprazole, impact the acidic tumor microenvironment, potentially influencing cancer cell behavior.
Ziad Joha, Oğuzhan Kalkan, Fatih Yulak, Mustafa Ergül, Mustafa Asım Gedikli   +4 more
wiley   +1 more source

Etiology and Therapeutic Strategies for Refractory Peptic Ulcers: A Comprehensive Review [PDF]

The Korean Journal of Helicobacter and Upper Gastrointestinal Research
The leading causes of refractory peptic ulcers are Helicobacter pylori infection and nonsteroidal anti-inflammatory drugs. Additionally, insufficient treatment for the suppression of gastric acid, smoking, alcohol consumption, and concomitant diseases ...
Su Bee Park
doaj   +1 more source

Type 2 and type 3 gastric neuroendocrine tumors have high risk of lymph node metastasis: Systematic review and meta‐analysis

Digestive Endoscopy, Volume 37, Issue 8, Page 834-843, August 2025.
Objectives Lymph node metastasis (LNM) is crucial in determining treatment strategies for gastric neuroendocrine tumors (gNETs). While type 3 is considered more aggressive than types 1 and 2 within the clinical subtype of gNETs, the supporting data were insufficient, due to their rarity. We aimed to study the prevalence and risk factors associated with
Yohei Ogata, Waku Hatta, Takeshi Kanno, Masahiro Saito, Xiaoyi Jin, Naoki Asano, Tomoyuki Koike, Akira Imatani, Yuhong Yuan, Atsushi Masamune   +9 more
wiley   +1 more source

Pancreatic neuroendocrine tumors in children and adolescents—Data from the German MET studies (1997–2023)

Journal of Neuroendocrinology, Volume 37, Issue 8, August 2025.
Abstract Pancreatic neuroendocrine tumors (panNETs) are rare pediatric malignancies with age‐specific clinical and biological features. Data on their presentation, management, and outcomes remain limited. This retrospective study analyzed 28 pediatric panNET cases from the German Malignant Endocrine Tumor (MET) Registry enrolled between 1997 and 2024 ...
Katharina Karges, Marina Kunstreich, Ulrich‐Frank Pape, Jörg Fuchs, Christian Vokuhl, Michael Abele, Dominik T. Schneider, Ines B. Brecht, Constantin Lapa, Michael C. Frühwald, Peter Vorwerk, Antje Redlich, Michaela Kuhlen   +12 more
wiley   +1 more source

Predictors of Mortality in Patients With Multiple Endocrine Neoplasia Type 1

Clinical Endocrinology, Volume 103, Issue 1, Page 50-56, July 2025.
SUMMARY Objective Multiple Endocrine Neoplasia Type 1 (MEN 1) is an autosomal dominant disease predisposing to hyperplasia and neoplasia in diverse endocrine tissues. Patients typically present with endocrine abnormalities before the age of 30 years and have reduced life expectancy.
Jasmine J. Zhu, John R Burgess
wiley   +1 more source

De novo Gastrinoma: A Case Report

GE: Portuguese Journal of Gastroenterology, 2019
Gastrinomas are neuroendocrine tumors characterized by gastrin overexpression – 80% are sporadic and 20% are associated with multiple endocrine neoplasia type 1.
Arsénio Barbosa, Filipa Gomes, Luísa Fonseca, Tiago Maia, Jorge Almeida   +4 more
doaj   +1 more source