Results 131 to 140 of about 14,154 (183)
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ZONA PELLUCIDA DOMAIN PROTEINS

Annual Review of Biochemistry, 2005
▪ Abstract  Many eukaryotic proteins share a sequence designated as the zona pellucida (ZP) domain. This structural element, present in extracellular proteins from a wide variety of organisms, from nematodes to mammals, consists of ∼260 amino acids with eight conserved cysteine (Cys) residues and is located close to the C terminus of the polypeptide ...
Luca, Jovine   +3 more
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The Fish Egg's Zona Pellucida

2018
All fish eggs are surrounded by an envelope, called the zona pellucida (ZP), that plays various roles during oogenesis, egg deposition, fertilization, and embryogenesis. The fish egg ZP consists of only a few proteins that are homologs of mammalian ZP proteins ZP1, ZP3, and ZP4. Unlike the situation in mammals, in fishes there are often multiple copies
Eveline S, Litscher, Paul M, Wassarman
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Immunocontraception with Zona pellucida Proteins

Cells Tissues Organs, 2000
The prospect of an immunological approach to contraception that would disrupt the process of fertilisation itself has resulted in a considerable interest into research in this area. It has been known for some time that antibodies raised against the zona pellucida (ZP) can suppress fertility very effectively.
M, Paterson   +3 more
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Surface properties of the zona pellucida

Journal of Experimental Zoology, 1980
AbstractStructural and sperm binding properties of the hamster zona pellucida (ZP) were investigated using the scanning electron microscope (SEM). The internal and external surfaces of the ZP were found to be morphologically dissimilar. The external surface displayed a fenestrated lattice‐like appearance, whereas the internal surface showed a regular ...
D M, Phillips, R M, Shalgi
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The Mouse Egg's Zona Pellucida

2018
All mammalian eggs are surrounded by a highly specialized extracellular matrix (ECM), called the zona pellucida (ZP), that functions before, during, and after fertilization. Unlike somatic cell ECM the mouse ZP is composed of three different proteins, ZP1-3, that are synthesized and secreted by growing oocytes and assembled into long interconnected ...
Paul M, Wassarman, Eveline S, Litscher
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Viscoelastic Characterization of Mouse Zona Pellucida

IEEE Transactions on Biomedical Engineering, 2013
The viscoelastic properties of the zona pellucida (ZP), which is the extracellular coat surrounding an oocyte/embryo, are evaluated in this study. Previous studies demonstrate that ZP mechanical properties change during oocyte maturation, fertilization, and early embryo development, but linear pure elastic models currently being used do not satisfy the
Kim, JS Kim, Jung-Sik, Kim, J Kim, Jung
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Structure and function of the zona pellucida: Identification and characterization of the proteins of the mouse oocyte's zona pellucida

Developmental Biology, 1980
Abstract The zona pellucida is an acellular coat which surrounds the plasma membrane of fully grown mammalian oocytes and which performs a variety of important functions during oogenesis, fertilization, and preimplantation development. In this investigation the proteins of the mouse oocyte's zona pellucida have been identified and characterized by ...
J D, Bleil, P M, Wassarman
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The multifunctional zona pellucida and mammalian fertilization

Journal of Reproductive Immunology, 2009
An early step in mammalian fertilization is species-restricted binding of sperm to the oocyte's zona pellucida (ZP), a thick extracellular coat. Sperm bind to the ZP of unfertilized oocytes, but not to the ZP of fertilized oocytes. Shortly after binding to the unfertilized oocyte ZP, sperm undergo the acrosome reaction (AR).
Paul M, Wassarman, Eveline S, Litscher
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Antibody reactivity with porcine zona pellucida

Journal of Reproductive Immunology, 1985
A comparative study on anti-zona antibody activities in the sera from clinically defined categories of patients registered at the WHO Reference Bank for Reproductive Immunology was performed at five different laboratories with different detection methods.
T, Mori   +8 more
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Mouse zona pellucida genes and glycoproteins

Cytogenetic and Genome Research, 2004
The zona pellucida (ZP) is a thick extracellular coat that surrounds all mammalian eggs. The ZP plays important roles during oogenesis, fertilization, and preimplantation development. The mouse ZP consists of only three glycoproteins, called ZP1, ZP2, and ZP3. All three glycoproteins are essential structural components of the ZP.
P M, Wassarman, L, Jovine, E S, Litscher
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