Results 101 to 110 of about 12,167 (193)

A Microglia–Astrocyte Signaling Axis Regulates Astrocyte Piezo1 Expression and Inflammatory Responses

Glia, Volume 74, Issue 9, September 2026.
Activated microglia‐derived inflammatory signals drive astrocytic Piezo1 expression in both in vitro and in vivo models. Piezo1 upregulation modulates astrocytic Ca2+ dynamics and inflammatory gene expression, thereby limiting microglial activation. ABSTRACT Structural tissue alterations in numerous brain disorders can initiate mechanosensory signaling
Yanyang Bai, Hyun B. Choi, Stefan Wendt, Morgan Towriss, Ada J. Lin, Christopher J. Groten, Ivy Cui, Haakon B. Nygaard, Brian A. MacVicar   +8 more
wiley   +1 more source

Residence Near Agricultural Crops at Birth and Risk of Adult Testicular Germ Cell Tumors: A French Nationwide Case–Control Study Using Historical Aerial GIS Data

International Journal of Cancer, Volume 159, Issue 5, Page 1153-1166, 1 September 2026.
As the incidence of testicular germ cell tumors (TGCTs) rises, prenatal exposure to agricultural pesticides may represent an important risk factor. Here, geographic information system‐based measures of farmland proximity at birth were used as a proxy for early‐life pesticide exposure in France, a major pesticide consumer.
Aurélie M. N. Danjou, Astrid Coste, Lény Grassot, Elodie Faure, Carlos Crispim‐Junior, Laure Tougne Rodet, Olivia Pérol, Rémi Béranger, Jeanne Perrin, Barbara Charbotel, Joachim Schüz, Béatrice Fervers, the TESTIS study group, Helen Boyle, Aude Fléchon, Elodie Belladame, Véronique Drouineaud, Céline Chalas, Myriam Virlouvet, Lucile Ferreux, Guillemette Perier, Pauline Peretout, Diane Rivet, Sandrine Rulle, Florence Eustache, Nathalie Sermondade, Marine Durand, Rachel Levy, Isabelle Berthaut, Jacqueline Saias‐Magnan, Catherine Metzler‐Guillemain, Carole Daoud‐Deveze, Louis Bujan, Myriam Daudin, Florence Brugnon, Valérie Bruhat, Cyril Bouche, Isabelle Kocsinski, Marius Teletin, Françoise Schmitt, Nathalie Guyomard, Aline Papaxanthos, Volcy Soula, Sandrine Giscard d’Estaing, Pascale Dehee, Delphine Yalcinkaya, Céline Bouillon, Cynthia Frapsauce, Anne Viallon, Bérengère Ducrocq, Marie‐Ange Clarotti, Ethel Szerman, Amélie Ancelle, Oxana Blagosklonov, Séverine Bey, Célia Ravel, Ségolène Veau, Agnès Letremy, Patricia Fauque, Julie Barberet, Stéphanie Lattes, Emmanuelle Thibault, Catherine Diligent, Christel Hersant, Vanessa Loup‐Cabaniols, Anna Gala, Sylvianne Hennebicq, Julien Bessonnat, Marie‐Claude Blocquaux, Brigitte Dananché, Johan Spinosi, Matthieu Dubuis, Charlotte Carretero, Etienne Durand, Bénédicte Thomas, Rémi Ratajczak   +75 more
wiley   +1 more source

Pediatric Tuberculosis in North Kivu: The Urgency of a Targeted Response to a Forgotten Childhood Disease

Public Health Challenges, Volume 5, Issue 3, September 2026.
ABSTRACT Pediatric tuberculosis remains a neglected health emergency, particularly in fragile contexts such as North Kivu province in the Democratic Republic of Congo. While more than one million children contract tuberculosis each year worldwide, the majority of cases remain underdiagnosed, resulting in preventable morbidity and mortality.
Germain Cebweru Murhola, Christian Tague, Dujardin Makeda, Joshua Ekouo, Hermann Yokolo, Aymar Akilimali, Criss Koba Mjumbe   +6 more
wiley   +1 more source

From fossil to bio‐circular plastics: the environmental benefits of bio‐attributed acrylonitrile butadiene styrene in single‐use cystoscopes

BJU International, Volume 138, Issue 3, Page 480-490, September 2026.
Background Single‐use cystoscopes are increasingly adopted in urology, but concerns regarding their environmental footprint persist. Substituting conventional fossil‐based plastics with bio‐attributed materials may reduce life cycle impacts, yet the magnitude and robustness of this benefit remain uncertain.
Arthur Peyrottes, Thibaut Long Depaquit, Maxime Pattou, Elliot Tokarski, Alessandro Uleri, Richard Mallet, Michael Baboudjian   +6 more
wiley   +1 more source

Optimization of novel compounds using computer‐aided drug design for treatment of cardiac arrhythmia

British Journal of Pharmacology, Volume 183, Issue 17, Page 5407-5420, September 2026.
Background and Purpose Loss‐of‐function mutations of the voltage‐gated Kv7.1 (KCNQ/KCNE1) channels lead to cardiac arrhythmia such as long QT syndrome, characterized by a prolonged QT interval . One strategy to correct the prolonged QT interval is to design molecules that activate KCNQ1/KCNE1 channels and restore the QT interval.
Jessica Jowais, Laura M. Castro‐Gonzalez, Alessia Golluscio, D. Peter Tieleman, H. Peter Larsson   +4 more
wiley   +1 more source

[Factors associated with acceptance of COVID-19 vaccination in the Kokolo health zone in Kinshasa, Democratic Republic of Congo (DRC)]. [PDF]

Med Trop Sante Int
Amisi Kengea L, Masamba Bikoki W, Nsinga Bungiena JC, Kape Kalume JJ.   +3 more
europepmc   +1 more source

Evaluation of High‐Resolution CORDEX‐CMIP6 Ocean Temperature Simulations for the Great Barrier Reef

Journal of Geophysical Research: Atmospheres, Volume 131, Issue 15, 16 August 2026.
Abstract Longevity of the Great Barrier Reef (GBR) relies on specific oceanic and atmospheric conditions that are quickly deteriorating under climate change. While global climate models (GCMs) provide insights into large‐scale processes, they often lack the resolution to capture regional nuances affecting the GBR.
Sun W. Kim, Jozef Syktus, Marcus Thatcher, Ralph Trancoso   +3 more
wiley   +1 more source

[Profile of mpox cases identified during surveillance of the Kokolo health zone in Kinshasa (DRC) from August to November 2024]. [PDF]

Med Trop Sante Int
Amisi Kengea L, Ihekambangu Ngwakaha B, Masamba Bikoki W, Ndumbi Temuangudi V, Nsinga Bungiena JC, Kape Kalume JJ, Mbuyi Mutombe A, Wumba Mavinga A.   +7 more
europepmc   +1 more source

NLRC5‐Deficient Macrophages Promote a Tumor‐Permissive Phenotype via AXL‐ and MERTK‐Mediated Efferocytosis

The FASEB Journal, Volume 40, Issue 15, 15 August 2026.
Defective NLRC5 signaling in macrophages drives TAM phenotype and anti‐inflammatory responses via STAT3/ERK, leading to tumor‐permissive conditions and gastric lymphoid neogenesis during Helicobacter infection. ABSTRACT The innate immune protein NLRC5 plays a key role in cancer immune surveillance.
Shambel Araya Haile, Alessandra Gatta, Nina Colon, Dana J. Philpott, Thomas A. Kufer, Le Ying, Dongmei Tong, Richard L. Ferrero   +7 more
wiley   +1 more source

Delineation of onchocerciasis operational transmission zones of Burkina Faso. [PDF]

Int Health
Koala L, Achille NS, Justin C, Clarisse B, Mathias O, Aimé AG, Karim S, Moussa SS, Iniaki T, Paul BR, Montant KC, Soungalo T, Daniel BA, Dabiré RK.   +13 more
europepmc   +1 more source