Results 31 to 40 of about 161,238 (304)
Erratic and blood vessel-guided migration of astrocyte progenitors in the cerebral cortex
Nature Communications, 2022 During development, astrocytes are generated from radial glia, and migrate to the cortical plate, but the process of astrocyte migration during development is not fully understood.
Hidenori Tabata +16 more
doaj +1 more source
Bathymetry of the Indonesian Sunda margin-relating morphological features of the upper plate slopes to the location and extent of the seismogenic zone [PDF]
Natural Hazards and Earth System Sciences, 2010 Earthquake history shows that the Sunda subduction zone of the Indonesian margin produces great earthquakes offshore Sumatra, whereas earthquakes of comparable magnitude are lacking offshore Java and the Lesser Sunda islands.
A. Krabbenhoeft +7 more
doaj +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Utilizing the phenomenon of diffraction for noise protection of roadside objects
Noise MappingPresented here is a constructive solution to the challenge of utilizing the diffraction phenomenon for mitigating noise around roadside objects caused by the movement of vehicles on transportation routes.
Louda Petr +4 more
doaj +1 more source
Wood zone plate fishnet metalens
EPJ Applied Metamaterials, 2015 Fresnel-zone plate lenses provide focusing performance while having low profile. Unfortunately, they usually display higher reflection losses than conventional dielectric lenses.
Orazbayev Bakhtiyar +2 more
doaj +1 more source
Research on prediction model of slot milling forces for hollow thin-walled welded structural parts
Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2023 The milling force of hollow thin-walled welded structural parts varies greatly at each position, and the analytical model was less studied, which affects the prediction accuracy of milling force.
Jiaheng MA +5 more
doaj +1 more source
Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source