Results 41 to 50 of about 714,548 (303)

Revised Pacific-Antarctic plate motions and geophysics of the Menard Fracture Zone [PDF]

open access: yes, 2008
A reconnaissance survey of multibeam bathymetry and magnetic anomaly data of the Menard Fracture Zone allows for significant refinement of plate motion history of the South Pacific over the last 44 million years.
Atwater   +47 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

The application of Fresnel zone plate based projection in optofluidic microscopy [PDF]

open access: yes, 2008
Optofluidic microscopy (OFM) is a novel technique for low-cost, high-resolution on-chip microscopy imaging. In this paper we report the use of the Fresnel zone plate (FZP) based projection in OFM as a cost-effective and compact means for projecting the ...
Cui, Xiquan   +3 more
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Wood zone plate fishnet metalens

open access: yesEPJ Applied Metamaterials, 2015
Fresnel-zone plate lenses provide focusing performance while having low profile. Unfortunately, they usually display higher reflection losses than conventional dielectric lenses.
Orazbayev Bakhtiyar   +2 more
doaj   +1 more source

Research on prediction model of slot milling forces for hollow thin-walled welded structural parts

open access: yesJournal of Advanced Mechanical Design, Systems, and Manufacturing, 2023
The milling force of hollow thin-walled welded structural parts varies greatly at each position, and the analytical model was less studied, which affects the prediction accuracy of milling force.
Jiaheng MA   +5 more
doaj   +1 more source

Asymmetric continental deformation during South Atlantic rifting along southern Brazil and Namibia [PDF]

open access: yes, 2017
Plate restoration of South America and Africa to their pre-breakup position faces the problem of gaps and overlaps between the continents, an issue commonly solved with implementing intra-plate deformation zones within South America.
Koehn, Daniel   +2 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Investigation of strain measurements in (curved) wide plate specimens using digital image correlation and finite element analysis [PDF]

open access: yes, 2012
Some pipelines face global plastic straining due to the nature of their installation process or harsh environmental conditions during operation. The ability of the girth welds to withstand these plastic strains is often evaluated on the basis of wide ...
De Waele, Wim   +3 more
core   +1 more source

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