Results 71 to 80 of about 479,302 (269)
On July 22nd, 2001, there was the third shooting in a month. The municipality of Rotterdam declared the area around Rotterdam Centraal Station a zero-tolerance zone, installed 360o security cameras, and imposed the umpteenth ban on disreputable ...
Elma van Boxel +2 more
doaj +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Termites are widely dispersed throughout the tropics and attain the highest diversity and abundance in the rainforests of Africa. Understanding their diversity in areas with human activities can provide insights into the local biodiversity and health of ...
Adeoye Abubakar Abdullahi +2 more
doaj +1 more source
Age-related neurodegenerative diseases involve reduced cell numbers and impaired behavioral capacity. Neurodegeneration and behavioral deficits also occur during aging, and notably in the absence of disease.
Sarah G Donofrio +5 more
doaj +1 more source
A survey of the Seybouse wadi (North-Eastern Algeria) between 2008 and 2011 was conducted in 26 sampling sites located on the main river and its tributaries using chironomids. From 3264 collected larvae, forty-five chironomid species were identified, and
Nadjla Chaib +5 more
doaj +1 more source
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura +19 more
wiley +1 more source
Background/Objectives: The aim of this study was to investigate the acute effect of isometric and plyometric combined activation prior to the endurance performance assessed with the 30-15 Intermittent Fitness Test (30-15 IFT) and cardiovascular ...
Dawid Koźlenia +2 more
doaj +1 more source
21 pages, 18 PostScript ...
Veerman, J. J. P. +3 more
openaire +3 more sources
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source

