Results 61 to 70 of about 21,302 (208)

Modulation of Salmonella virulence by a novel SPI-2 injectisome effector that interacts with the dystrophin-associated protein complex

mBio
The injectisome encoded by Salmonella pathogenicity island 2 (SPI-2) had been thought to translocate 28 effectors. Here, we used a proteomic approach to characterize the secretome of a clinical strain of invasive non-typhoidal Salmonella enterica serovar
Xiu-Jun Yu, Haixia Xie, Yan Li, Mei Liu, Ruhong Hou, Alexander V. Predeus, Blanca M. Perez Sepulveda, Jay C. D. Hinton, David W. Holden, Teresa L. M. Thurston   +9 more
doaj   +1 more source

Effects of an Organic Acid Blend on Growth Performance, Redox Homeostasis, and Intestinal Microbiota of Broilers in an Antibiotic‐Free Production System Under Winter Environmental Challenges

Animal Research and One Health, EarlyView.
Schematic summary of the effects of organic acids on growth performance and gut health‐related parameters in broilers. ABSTRACT This study was conducted to evaluate the effects of an organic acid blend on growth performance, redox homeostasis, and intestinal microbiota of broilers raised in an antibiotic‐free system during the winter season in China ...
Rong‐Hui Huang, Hong‐Lin Li, Yu Zhang, Jie Wang, Shao‐Qing Wang, Xue‐Wu Li, Lane Pineda, Xiang‐Dong Kuang, Giseli Heim, Mahmoud Mohamed Khalil, Lv‐Hui Sun, Zhang‐Chao Deng   +11 more
wiley   +1 more source

Quantification of Zonula Occludens-1 mRNA expression in cultured bovine retinal endothelial cells, using SYBR green real-time PCR [PDF]

, 2008
A simple and rapid real-time reverse transcription-PCR (RT-PCR) technique using SYBR green fluorescence was developed to quantify Zonula Occludens-1 (ZO-1) mRNA expression in histamine-treated cultured bovine retinal microvessel endothelial cells.
Qvist, R., Muniandy, S., Yaiw, K.C., Rayappan, A.V., Ismail, I.S., Wong, K.T., Chook, J.B.   +6 more
core   +1 more source

Gut‐microbiota‐brain Axis and post‐traumatic epilepsy

Epilepsia Open, EarlyView.
Abstract There has been growing evidence that perturbations in gut‐microbiota‐brain axis (GMBA) are involved in mechanisms of chronic sequelae of traumatic brain injury (TBI). This review discusses the connection between GMBA and post‐traumatic epilepsy (PTE), the latter being a common outcome of TBI.
Andrey Mazarati
wiley   +1 more source

Targeting Cx43 and N-cadherin, which are abnormally upregulated in venous leg ulcers, influences migration, adhesion and activation of Rho GTPases.

, 2012
Venous leg ulcers can be very hard to heal and represent a significant medical need with no effective therapeutic treatment currently ...
Thrasivoulou, C, Serena Thomas, Becker, DL, Christopher Thrasivoulou (165615), Serrano, AE, Serrano Antonio E., White Alexis, Cormie Peter, Becker David L., Thomas Serena, Cormie, P, Peter Cormie (165594), Thrasivoulou Christopher, Anthony R. J. Phillips (165633), Alexis White, Wang Chiuhui Mary, Shay O'Neill (165605), Kieran T Power, Christopher Thrasivoulou, Rebecca Hu, Shay O'Neill, David L Becker, David L. Becker (165638), Anthony R J Phillips, Kieran T. Power (165618), White, A, Alexis White (165623), O'Neill Shay, Serena, T, Antonio E. Serrano (165597), Power Kieran T., Peter Cormie, Chiuhui Mary Wang (165610), Thomas Serena (165628), Rebecca Hu (165601), Mendoza-Naranjo, A, Wang, CM, Antonio E Serrano, Hu Rebecca, Phillips Anthony R. J., Ariadna Mendoza-Naranjo (165592), Hu, R, O'Neill, S, Power, KT, Ariadna Mendoza-Naranjo, Chiuhui Mary Wang, Mendoza-Naranjo Ariadna, Phillips, AR   +47 more
core   +1 more source

Mena/VASP and αII-Spectrin complexes regulate cytoplasmic actin networks in cardiomyocytes and protect from conduction abnormalities and dilated cardiomyopathy [PDF]

, 2013
BACKGROUND: In the heart, cytoplasmic actin networks are thought to have important roles in mechanical support, myofibrillogenesis, and ion channel function.
Benz, PM, Frantz, Stefan, Merkel, CJ, Offner, Kristin, Fleming, Ingrid, Feller, Stephan M., Renné, T, Gambaryan, Stepan, Unger, A, Linke, Wolfgang A., Fischer, T, Merkel, Carla J., Bayer, B, Schuh, K, Benz, Peter M., Wagner, Helga, Ullrich, Melanie, Linke, WA, Bayer, Barbara, Ullrich, M, Offner, K, Renné, Thomas, Abeßer, M, Ursitti, Jeanine A., Frantz, S, Adham, Ibrahim M., Unger, Andreas, Adham, IM, Feller, SM, Fischer, Tobias, Wagner, H, Abeßer, Marco, Schuh, Kai, Gambaryan, S, Fleming, I, Ursitti, JA   +35 more
core   +1 more source

Resveratrol Ameliorates Allergic Rhinitis by Activating SIRT1 to Disrupt the Mitochondrial ROS‐Inflammation Vicious Cycle

Flavour and Fragrance Journal, EarlyView.
This study demonstrates that resveratrol alleviates allergic rhinitis by activating SIRT1, thereby disrupting the mitochondrial ROS‐inflammatory cycle, improving mitochondrial function, promoting anti‐inflammatory M2 macrophage polarisation, and reducing epithelial oxidative damage.
Xinyu Zhou, Yi Yue, Wenwen Qi, Wenqing Zhu, Xinran Liu, Rongcui Sui, Xuanchen Zhou   +6 more
wiley   +1 more source

Calcitonin Receptor-Zonula Occludens-1 Interaction Is Critical for Calcitonin-Stimulated Prostate Cancer Metastasis. [PDF]

, 2016
The role of neuroendocrine peptide calcitonin (CT) and its receptor (CTR) in epithelial cancer progression is an emerging concept with great clinical potential.
Kenneth A Iczkowski, Girish V. Shah (370657), Arvind Thakkar (2548525), Thakkar, Arvind, Vijaybasker Lakshmikanthan, Arvind Thakkar, Girish V Shah, Shibu Thomas (2548534), Ahmed Aljameeli, Aljameeli, Ahmed, Vijaybasker Lakshmikanthan (2548531), Lakshmikanthan, Vijaybasker, Thomas, Shibu, Shibu Thomas, Ahmed Aljameeli (2548528), Shah, Girish, Iczkowski, Kenneth, Kenneth A. Iczkowski (370739)   +17 more
core   +1 more source

Spatial Overlap of Claudin- and Phosphatidylinositol Phosphate-Binding Sites on the First PDZ Domain of Zonula Occludens 1 Studied by NMR

Molecules, 2018
Background: The tight junction is an intercellular adhesion complex composed of claudins (CLDs), occludin, and the scaffolding proteins zonula occludens 1 (ZO-1) and its two paralogs ZO-2 and ZO-3.
Hidekazu Hiroaki, Kaori Satomura, Natsuko Goda, Yukako Nakakura, Minami Hiranuma, Takeshi Tenno, Daizo Hamada, Takahisa Ikegami   +7 more
doaj   +1 more source

Beyond Gut Modulation: A Critical Review of the Therapeutic Potential, Safety, and Clinical Prospects of Natural Polysaccharides for IBD

Food Safety and Health, EarlyView.
In this review, we critically summarized the application of natural polysaccharides (NPs) for the treatment of IBD. This approach combines, in a unique way (right), the basic structure–activity relationships of NPs from different origins (left) with their multipronged mode of action, which involves modulation of the gut microbiota and other ...
Felix Danso, A. M. Abd El‐Aty, Kwaku Amoah, Xianghong Ju   +3 more
wiley   +1 more source