Results 21 to 30 of about 37,096 (257)

Identification of a TRBD zinc finger-interacting protein in Giardia duodenalis and its regulation of telomerase

Parasites & Vectors, 2019
Background Giardia duodenalis causes giardiasis, with diarrhea as the primary symptom. The trophozoite proliferation of this zoonotic parasite is mainly affected by telomerase, although the mechanism of telomerase regulation has not been thoroughly ...
Jing-Tong Zheng, Nan Zhang, Yan-Hui Yu, Peng-Tao Gong, Xian-He Li, Na Wu, Can Wang, Xiao-Cen Wang, Xin Li, Jian-Hua Li, Xi-Chen Zhang   +10 more
doaj   +1 more source

Development of an LFD-RPA Assay for Rapid Detection of Pentatrichomonas hominis Infection in Dogs

Current Issues in Molecular Biology, 2023
Pentatrichomonas hominis is a trichomonad protozoan that infects the cecum and colon of humans and other mammals. It is a zoonotic pathogen that causes diarrhea in both animals and humans. As companion animals, dogs infected with P.
Yao Rong, Xichen Zhang, Xuejiao Chen, Jianhua Li, Pengtao Gong, Xiaocen Wang, Xin Li, Xu Zhang, Taotao Yue, Hongbo Zhang, Xiaofei Zhou, Nan Zhang   +11 more
doaj   +1 more source

Host Prdx6 contributing to the intracellular survival of Brucella suis S2 strain

BMC Veterinary Research, 2019
Background Brucellosis is a worldwide zoonotic infectious disease that is transmitted in various ways and causes great harm to humans and animals. The brucellosis pathogen is Brucella, which mainly resides in macrophage cells and survives and replicates ...
Lu-Lu Wang, Xiao-Feng Chen, Pan Hu, Shi-Ying Lu, Bao-Quan Fu, Yan-Song Li, Fei-Fei Zhai, Dan-Di Ju, Shi-Jun Zhang, Yi-Ming Shui, Jiang Chang, Xiao-Long Ma, Bing Su, Yu Zhou, Zeng-Shan Liu, Hong-Lin Ren   +15 more
doaj   +1 more source

Disruption of Epithelial Barrier of Caco-2 Cell Monolayers by Excretory Secretory Products of Trichinella spiralis Might Be Related to Serine Protease

Frontiers in Microbiology, 2021
The physical barrier is composed of epithelial cells which are joined together through intercellular connections. It serves to prevent pathogenic microorganisms from departing the intestinal lumen to invade the host. The excretory secretory (ES) products
Chengyao Li, Xue Bai, Xiaolei Liu, Yuanyuan Zhang, Lei Liu, Lixiao Zhang, Fengyan Xu, Yong Yang, Mingyuan Liu, Mingyuan Liu   +9 more
doaj   +1 more source

Discrepancy in Response of Mouse Dendritic Cells against BCG: Weak Immune Effects of Plasmacytoid Dendritic Cells Compared to Classical Dendritic Cells despite the Uptake of Bacilli

Tropical Medicine and Infectious Disease, 2023
Tuberculosis (TB), a zoonosis characterized by chronic respiratory infections, is mainly caused by Mycobacterium tuberculosis and is associated with one of the heaviest disease burdens in the world.
Chuang Meng, Jun Liu, Xilong Kang, Zhengzhong Xu, Shuangyuan Xu, Xin Li, Zhiming Pan, Xiang Chen, Xinan Jiao   +8 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Entry of Challenge Virus Standard (CVS) -11 into N2a cells via a clathrin-mediated, cholesterol-, dynamin-, pH-dependent endocytic pathway

Virology Journal, 2019
Background Rabies virus (RABV), a member of Lyssavirus of Rhabdoviridae family, is a kind of negative-strand RNA virus. The zoonosis caused by RABV leads to high mortality in animals and humans.
Jie Gao, Xinyu Wang, Mingxin Zhao, Enhua Liu, Ming Duan, Zhenhong Guan, Yidi Guo, Maolin Zhang   +7 more
doaj   +1 more source

TREM2 Regulates High Glucose-Induced Microglial Inflammation via the NLRP3 Signaling Pathway

Brain Sciences, 2021
Background: TREM2 expressed on microglia plays an important role in modulating inflammation in neurodegenerative diseases. It remains unknown whether TREM2 modulates hyperglycemia-induced microglial inflammation.
Yuan Li, Weihong Long, Menghan Gao, Fangtai Jiao, Zecai Chen, Mingyuan Liu, Lu Yu   +6 more
doaj   +1 more source

MFPD: A Multiple Fungal Pathogen Detection Pipeline Across Diverse Habitats

Advanced Science, EarlyView.
The MFPD pipeline integrates a comprehensive ITS reference database of fungal pathogens, optimized parameters, and algorithms tailored for both full‐length and subregion sequences that balance accuracy and computational efficiency; it enables high‐throughput, species‐level identification from amplicon sequencing data, supporting large‐scale ...
Yi Shen, Xinrun Yang, Jiabao Yu, Yaozhong Zhang, Tianjie Yang, Yang Gao, Xiaofang Wang, Alexandre Jousset, Waseem Raza, Fang‐Jie Zhao, Qirong Shen, Gaofei Jiang, Zhong Wei, Yangchun Xu   +13 more
wiley   +1 more source

Effect of Circular RNA hsa_circ_004389 on Replication of Influenza A Virus

Guangdong nongye kexue, 2022
【Objective】Based on the preliminary transcriptome profiles of A549 cells responding to influenza A virus (IAV) infection, one of the most significantly up-regulated host circular RNA(circRNA), hsa_circ_004389, was selected to further validate its ...
Shu ZHANG, Xiaohang YU, Le ZHANG, Ning SU, Lili ZHAO, Ming DUAN   +5 more
doaj   +1 more source