Results 41 to 50 of about 88,011 (296)
Advanced Science, EarlyView.RNF213 is characterized as a dual‐functional antiviral effector. It directly mediates the degradation of the influenza A virus nucleoprotein (NP) while simultaneously activating the MDA5‐mediated innate immune signaling pathway. This coordinated response establishes a powerful host defense system against viral infection. ABSTRACT Influenza A virus (IAV)
Haoning Li +5 more
wiley +1 more source
Host Prdx6 contributing to the intracellular survival of Brucella suis S2 strain
BMC Veterinary Research, 2019 Background Brucellosis is a worldwide zoonotic infectious disease that is transmitted in various ways and causes great harm to humans and animals. The brucellosis pathogen is Brucella, which mainly resides in macrophage cells and survives and replicates ...
Lu-Lu Wang +15 more
doaj +1 more source
, 2010 Zoonosis adalah penyakit-penyakit dan infeksi yang secara alami dapat ditularkan dari hewan-hewan vertebrata ke manusia dan atau sebaliknya. Pengertian tersebut juga mencakup keadaan dimana suatu organisme dapat hidup baik di dalam tubuh manusia maupun ...
Wijayanti, T. (Tri)
core
Chlamydia psittaci infection in canaries heavily infested by Dermanyssus gallinae [PDF]
, 2011 Dermanyssus gallinae is a haematophagous ectoparasite responsible for anemia, weight loss, dermatitis and a decrease in egg production. Dermanyssus gallinae may play a role in the modulation of the host immune system, maybe predisposing the host to some ...
Cafiero, Maria Assunta +5 more
core +2 more sources
Medwave, 2003 Ecological, climatic and sociocultural changes, have enhanced the number of known zoonoses being over 200 at the present. Transmission of infectious agents from animals to man occurs by direct contact with the animal, o by ingestion, inhalation or inoculation of infectious agent. In the Región Metropolitana 71 percent of houses with children have pets,
openaire +2 more sources
Discovery of H2 Receptor Antagonists as Colistin Enhancers by Targeting Acid Stress Response
Advanced Science, EarlyView.This study identifies YqgB as a key target for restoring colistin susceptibility in mcr‐positive pathogens under acidic conditions by remodeling phospholipid composition and reducing LPS modification. Deep learning‐based screening reveals H2 receptor antagonists as novel colistin adjuvants. Further investigations indicate that ranitidine and famotidine
Jinju Cai +7 more
wiley +1 more source
Virology Journal, 2019 Background Rabies virus (RABV), a member of Lyssavirus of Rhabdoviridae family, is a kind of negative-strand RNA virus. The zoonosis caused by RABV leads to high mortality in animals and humans.
Jie Gao +7 more
doaj +1 more source
TREM2 Regulates High Glucose-Induced Microglial Inflammation via the NLRP3 Signaling Pathway
Brain Sciences, 2021 Background: TREM2 expressed on microglia plays an important role in modulating inflammation in neurodegenerative diseases. It remains unknown whether TREM2 modulates hyperglycemia-induced microglial inflammation.
Yuan Li +6 more
doaj +1 more source
Assessment of porcine endogenous retrovirus transmission across an alginate barrier used for the encapsulation of porcine islets [PDF]
, 2018 BACKGROUND: Subcutaneous implantation of a macroencapsulated patch containing human allogenic islets has been successfully used to alleviate type 1 diabetes mellitus (T1DM) in a human recipient without the need for immunosuppression.
Crossan, Claire +4 more
core +1 more source
PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe
Advanced Science, EarlyView.This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao +14 more
wiley +1 more source