Results 11 to 20 of about 40,088 (308)

Zymosan attenuates melanoma growth progression, increases splenocyte proliferation and induces TLR-2/4 and TNF-α expression in mice

open access: yesJournal of Inflammation, 2018
Background Melanoma is one of the most common types of skin malignancies. Since current therapies are suboptimal, considerable interest has focused on novel natural-based treatments.
Mehdi Taghavi   +8 more
doaj   +2 more sources

Ouabain Modulates Zymosan‐Induced Peritonitis in Mice [PDF]

open access: yesMediators of Inflammation, 2015
Ouabain, a potent inhibitor of the Na+, K+‐ATPase, was identified as an endogenous substance. Recently, ouabain was shown to affect various immunological processes. We have previously demonstrated the ability of ouabain to modulate inflammation, but little is known about the mechanisms involved.
Jacqueline Alves Leite   +8 more
openaire   +5 more sources

Zymosan-a Protects the Hematopoietic System from Radiation-Induced Damage by Targeting TLR2 Signaling Pathway

open access: yesCellular Physiology and Biochemistry, 2017
Background/Aims: The hematopoietic system is vulnerable to ionizing radiation and is often severely damaged by radiation. Molecules affecting radioresistance include Toll-like receptor 2.
Jicong Du   +11 more
doaj   +2 more sources

Inflammation and resolution are associated with upregulation of fatty acid β-oxidation in Zymosan-induced peritonitis. [PDF]

open access: yesPLoS ONE, 2013
Inflammation is a fundamental defensive response to harmful stimuli. However, it can cause damage if it does not subside. To avoid such damage, organisms have developed a mechanism called resolution of inflammation.
Yusuke Fujieda   +7 more
doaj   +2 more sources

Activation-Inactivation Cycling of Rab35 and ARF6 Is Required for Phagocytosis of Zymosan in RAW264 Macrophages

open access: yesJournal of Immunology Research, 2015
Phagocytosis of zymosan by phagocytes is a widely used model of microbial recognition by the innate immune system. Live-cell imaging showed that fluorescent protein-fused Rab35 accumulated in the membranes of phagocytic cups and then dissociated from the
Youhei Egami   +5 more
doaj   +2 more sources

Collagen hydrolysate inhibits zymosan-induced inflammation

open access: yesExperimental Biology and Medicine, 2013
During the past years, evidence accumulated showing that glycine comprises anti-inflammatory activities. These effects occur, at least in part, via the activation of glycine-gated chloride channels (GlyR). Glycine is one of the major structural units of collagen, making up about 30% of the amino acids.
Miranda Cozijnsen   +3 more
openaire   +5 more sources

Zymosan-mediated inflammation impairs in vivo reverse cholesterol transport[S]

open access: yesJournal of Lipid Research, 2011
Inflammation has been proposed to impair HDL function and reverse cholesterol transport (RCT). We investigated the effects of inflammation mediated by zymosan, a yeast glucan, on multiple steps along the RCT pathway in vivo and ex vivo.
Priya Malik   +5 more
doaj   +2 more sources

Efeito de inibidores da sintase de óxido nítrico na dor inflamatória articular e influxo celular da artrite induzida por zymosan em ratos [PDF]

open access: diamondRevista Brasileira de Reumatologia, 2003
OBJETIVO: Investigar o papel do óxido nítrico (NO) no influxo celular (IC) e a incapacitação articular (IA) na artrite por zymosan (AZy). MÉTODOS: Ratos Wistar receberam injeção de Zy (1mg) no joelho direito. Grupos-controles receberam salina.
Francisco Airton Castro da Rocha   +5 more
doaj   +2 more sources

Selective estrogen receptor modulator lasofoxifene suppresses spondyloarthritis manifestation and affects characteristics of gut microbiota in zymosan-induced SKG mice

open access: yesScientific Reports, 2021
Ankylosing spondylitis is a male-predominant disease and previous study revealed that estrogens have an anti-inflammatory effect on the spondyloarthritis (SpA) manifestations in zymosan-induced SKG mice.
Hyemin Jeong   +5 more
doaj   +1 more source

Anti-PCSK9 monoclonal antibody attenuates high-fat diet and zymosan-induced vascular inflammation in C57BL/6 mice by modulating TLR2/NF-ƙB signaling pathway [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2022
Objective(s): Excess intake of a high-fatty diet (HFD) together with zymosan administration mediates vasculitis response which leads to impaired serum lipid levels and causes arterial stiffness. In the development of new cholesterol-lowering medications,
Priyanka Arya   +3 more
doaj   +1 more source

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