Results 11 to 20 of about 40,088 (308)
Background Melanoma is one of the most common types of skin malignancies. Since current therapies are suboptimal, considerable interest has focused on novel natural-based treatments.
Mehdi Taghavi+8 more
doaj +2 more sources
Ouabain Modulates Zymosan‐Induced Peritonitis in Mice [PDF]
Ouabain, a potent inhibitor of the Na+, K+‐ATPase, was identified as an endogenous substance. Recently, ouabain was shown to affect various immunological processes. We have previously demonstrated the ability of ouabain to modulate inflammation, but little is known about the mechanisms involved.
Jacqueline Alves Leite+8 more
openaire +5 more sources
Background/Aims: The hematopoietic system is vulnerable to ionizing radiation and is often severely damaged by radiation. Molecules affecting radioresistance include Toll-like receptor 2.
Jicong Du+11 more
doaj +2 more sources
Inflammation and resolution are associated with upregulation of fatty acid β-oxidation in Zymosan-induced peritonitis. [PDF]
Inflammation is a fundamental defensive response to harmful stimuli. However, it can cause damage if it does not subside. To avoid such damage, organisms have developed a mechanism called resolution of inflammation.
Yusuke Fujieda+7 more
doaj +2 more sources
Phagocytosis of zymosan by phagocytes is a widely used model of microbial recognition by the innate immune system. Live-cell imaging showed that fluorescent protein-fused Rab35 accumulated in the membranes of phagocytic cups and then dissociated from the
Youhei Egami+5 more
doaj +2 more sources
Collagen hydrolysate inhibits zymosan-induced inflammation
During the past years, evidence accumulated showing that glycine comprises anti-inflammatory activities. These effects occur, at least in part, via the activation of glycine-gated chloride channels (GlyR). Glycine is one of the major structural units of collagen, making up about 30% of the amino acids.
Miranda Cozijnsen+3 more
openaire +5 more sources
Zymosan-mediated inflammation impairs in vivo reverse cholesterol transport[S]
Inflammation has been proposed to impair HDL function and reverse cholesterol transport (RCT). We investigated the effects of inflammation mediated by zymosan, a yeast glucan, on multiple steps along the RCT pathway in vivo and ex vivo.
Priya Malik+5 more
doaj +2 more sources
Efeito de inibidores da sintase de óxido nítrico na dor inflamatória articular e influxo celular da artrite induzida por zymosan em ratos [PDF]
OBJETIVO: Investigar o papel do óxido nítrico (NO) no influxo celular (IC) e a incapacitação articular (IA) na artrite por zymosan (AZy). MÉTODOS: Ratos Wistar receberam injeção de Zy (1mg) no joelho direito. Grupos-controles receberam salina.
Francisco Airton Castro da Rocha+5 more
doaj +2 more sources
Ankylosing spondylitis is a male-predominant disease and previous study revealed that estrogens have an anti-inflammatory effect on the spondyloarthritis (SpA) manifestations in zymosan-induced SKG mice.
Hyemin Jeong+5 more
doaj +1 more source
Anti-PCSK9 monoclonal antibody attenuates high-fat diet and zymosan-induced vascular inflammation in C57BL/6 mice by modulating TLR2/NF-ƙB signaling pathway [PDF]
Objective(s): Excess intake of a high-fatty diet (HFD) together with zymosan administration mediates vasculitis response which leads to impaired serum lipid levels and causes arterial stiffness. In the development of new cholesterol-lowering medications,
Priyanka Arya+3 more
doaj +1 more source