Immune response of hibernating European bats to a fungal challenge
Biology Open, 2019 Immunological responses of hibernating mammals are suppressed at low body temperatures, a possible explanation for the devastating effect of the white-nose syndrome on hibernating North American bats.
Marcus Fritze +5 more
doaj +1 more source
A monoclonal antibody recognizing very late activation antigen-4 inhibits eosinophil accumulation in vivo. [PDF]
, 1993 Using an in vivo test system, the role of the β1 integrin very late activation antigen-4 (VLA-4) in eosinophil accumulation in allergic and nonallergic inflammatory reactions was investigated.
Lobb, RR +3 more
core +1 more source
Optimisation of phagocytosis assay in rainbow trout (Oncorhynchus mykiss)
Veterinární Medicína, 2021 A phagocytosis assay is one of the most commonly used functional immunological methods. There are many possible ways of assessing leucocytes and their ability to ingest different particles.
H Minarova +6 more
doaj +1 more source
Frontiers in Nutrition, 2022 In this study, the effects of zymosan (HG, hydrolyzed glucan) on the structure and metabolism of fecal microbiota in Chinese healthy people was investigated by an in vitro simulated intestinal microecology fermentation model.
Xionge Pi +4 more
doaj +1 more source
Comparative lipid profiling dataset of the inflammation-induced optic nerve regeneration. [PDF]
, 2019 In adult mammals, retinal ganglion cells (RGCs) fail to regenerate following damage. As a result, RGCs die after acute injury and in progressive degenerative diseases such as glaucoma; this can lead to permanent vision loss and, eventually, blindness ...
Bhattacharya, Sanjoy K +5 more
core +1 more source
Consequences of altered eicosanoid patterns for nociceptive processing in mPGES-1-deficient mice [PDF]
, 2007 Cyclooxygenase-2 (COX-2)-dependent prostaglandin (PG) E2 synthesis in the spinal cord plays a major role in the development of inflammatory hyperalgesia and allodynia. Microsomal PGE2 synthase-1 (mPGES-1) isomerizes COX-2-derived PGH2 to PGE2.
Angioni, Carlo Federico +8 more
core +1 more source
Immunomodulatory properties of recombinant human granulocyte-macrophage colony-stimulating factor
Медицинская иммунология, 2023 Granulocyte-macrophage colony stimulating factor (GM-CSF) is a myelopoietic growth factor that exerts pleiotropic effect not only on the differentiation of immature progenitor cells into polymorphonuclear neutrophils, monocytes/macrophages and dendritic ...
G. M. Sysoeva +3 more
doaj +1 more source
Lipid Droplet-Driven Ribosome Collisions Trigger ZAKα-p38 Signaling to Accelerate Testicular Aging. [PDF]
Aging CellAging‐ and obesity‐driven lipid droplet accumulation in Sertoli cells induces ROS‐mediated ribosome collisions, activating the ZAKα‐p38 pathway to accelerate testicular aging. Pharmacological ZAKα inhibition with Nilotinib rescues age‐related testicular dysfunction, identifying ribotoxic stress as a therapeutic target.
Xu Y +18 more
europepmc +2 more sources
CXCR2 deficient mice display macrophage-dependent exaggerated acute inflammatory responses [PDF]
, 2017 CXCR2 is an essential regulator of neutrophil recruitment to inflamed and damaged sites and plays prominent roles in inflammatory pathologies and cancer. It has therefore been highlighted as an important therapeutic target.
A Mantovani +38 more
core +1 more source
Frontiers in Marine Science, 2022 The effects of dietary zymosan A on the growth performance and histological structure, digestive capacity, and microbiota were investigated in Litopenaeus vannamei, an important shrimp species used in aquaculture. L. vannamei (initial body weight = 0.41 ±
Yudong Zheng +10 more
doaj +1 more source