Results 31 to 40 of about 32,279 (227)

C13orf31 (FAMIN) is a central regulator of immunometabolic function. [PDF]

open access: yes, 2016
Single-nucleotide variations in C13orf31 (LACC1) that encode p.C284R and p.I254V in a protein of unknown function (called 'FAMIN' here) are associated with increased risk for systemic juvenile idiopathic arthritis, leprosy and Crohn's disease.

core   +2 more sources

Electroacupuncture alleviates zymosan-induced colorectal hypersensitivity. [PDF]

open access: greenJ Tradit Chin Med
Siting LI   +6 more
europepmc   +3 more sources

Anti-atherogenic properties associated with the antioxidant activity from the hydrophilic extracts of Halimeda incrassata (Chlorophyta, Bryopsidales) [PDF]

open access: yes, 2017
Seaweeds are a source of natural antioxidants having potential application in oxidative stress and associated diseases. In this work, anti-atherogenic properties associated with the antioxidant activity from the hydrophilic extracts of Halimeda ...
Claudina, Zaldívar-Munoz   +8 more
core   +1 more source

Experimental Validation of Alzheimer's Disease Targets Prioritized Through Systems Biology [PDF]

open access: yesAlzheimers Dement
Abstract Background Genome‐wide association studies and multi‐omic analyses of Alzheimer's disease have generated extensive lists of potential therapeutic targets. Effectively prioritizing these targets for drug development remains a significant challenge.
Cary G.
europepmc   +2 more sources

Formation of sustained antitumor effect in mice’s liver and spleen (CBA х C57BL/6)F1 after a single intravenous injection of zymosan-treated neutrophils

open access: yesActa Biomedica Scientifica, 2016
Application of zymosan in medicine is limited because of its side effects, since the native granules of zymosan directly activate serum complement components and phagocytic cells.
A. G. Lyubimov   +2 more
doaj   +1 more source

Neonatal Cystitis Makes Adult Female Rat Urinary Bladders More Sensitive to Low Concentration Microbial Antigens

open access: yesResearch and Reports in Urology, 2023
Ashley C Archer,1 Jennifer J DeBerry,2 Cary DeWitte,2 Timothy J Ness2 1University of Alabama at Birmingham School of Medicine, Birmingham, AL, USA; 2Department of Anesthesiology and Perioperative Medicine, University of Alabama at Birmingham, Birmingham,
Archer AC   +3 more
doaj  

Pyrogenic and neuroinflammatory properties of zymosan and its potential as an alternative to live yeast in antipyretic drug testing

open access: yesFACETS, 2019
Zymosan, an immunogenic cell wall extract of Saccharomyces cerevisiae has potential for use as an experimental pyrogen. However, the short-lived sickness responses noted with intraperitoneal and intra-articular administration of zymosan limits ...
Rachael Dangarembizi   +5 more
doaj   +1 more source

Noninflammatory Changes of Microglia Are Sufficient to Cause Epilepsy. [PDF]

open access: yes, 2018
Microglia are well known to play a critical role in maintaining brain homeostasis. However, their role in epileptogenesis has yet to be determined.
Adamo, Matthew A   +13 more
core   +2 more sources

Particulate Matter Exposure Impairs Systemic Microvascular Endothelium-Dependent Dilation [PDF]

open access: yes, 2004
Acute exposure to airborne pollutants, such as solid particulate matter (PM), increases the risk of cardiovascular dysfunction, but the mechanisms by which PM evokes systemic effects remain to be identified.
Barger, Mark   +4 more
core   +3 more sources

Nitric Oxide Production and Apoptosis Induction in T Cells through Stimulation of Mesenchymal Stem Cells with Zymosan [PDF]

open access: yesJournal of Kerman University of Medical Sciences, 2015
Background & Aims: Mesenchymal stem cells (MSCs) are non-hematopoietic multipotant cells, which multiply through attaching to culture plates. Toll-like receptors (TLRs) are inherent immune sensors and regulators of immunomodulatory activities of MSCs ...
Elham darabi   +3 more
doaj  

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