Results 31 to 40 of about 40,088 (308)
Synthesis, Characterization, and Biological Activity of Aminated Zymosan [PDF]
Zymosan (ZM), a naturally occurring insoluble macromolecule obtained from the cell wall of Saccharomyces cerevisiae, is used as a functional food (as dietary fiber), phagocytic stimulus, and immune potentiator. The present study aimed to increase its solubility and evaluate its immunological application. ZM was converted into soluble 6-amino-6-deoxy-β-(
Geetha Venkatachalam+2 more
openaire +4 more sources
Detection of the complement fragment C5a in inflammatory exudates from the rabbit peritoneal cavity using radioimmunoassay. [PDF]
We describe a radioimmunoassay for rabbit C5a and its use to obtain evidence of extravascular C5a generation in two inflammatory reactions in the peritoneal cavity.
Forrest, MJ, Jose, PJ, Williams, TJ
core +2 more sources
Amiloride reduces portal hypertension in rat liver cirrhosis [PDF]
Objective This study aimed to investigate the effect of amiloride on portal hypertension. Amiloride is known to inhibit Na(+)/H(+) exchangers on activated hepatic stellate cells.
Beitinger, Frigga+6 more
core +1 more source
Macrophage recognition of zymosan particles [PDF]
Zymosan particles have served as a model for recognition of microbes by the innate immune system for over 50 years. Zymosan induces inflammatory signals in macrophages through Toll-like receptors TLR2 and TLR6. In addition, phagocytic receptors on macrophages bind zymosan and stimulate particle engulfment. We have further examined the requirements for
openaire +3 more sources
Glutathione treatment protects the rat liver against injury after warm ischemia and Kupffer cell activation [PDF]
Background/Aim: The generation of reactive oxygen species by activated Kupffer cells (KC) may contribute to reperfusion injury of the liver during liver transplantation or resection.
Baron, A.+5 more
core +1 more source
Immune response of hibernating European bats to a fungal challenge
Immunological responses of hibernating mammals are suppressed at low body temperatures, a possible explanation for the devastating effect of the white-nose syndrome on hibernating North American bats.
Marcus Fritze+5 more
doaj +1 more source
Complement (C) activation can underlie the infusion reactions to liposomes and other nanoparticle-based medicines, a hypersensitivity syndrome that can be partially reproduced in animal models.
László Dézsi+8 more
doaj +1 more source
In this study, the effects of zymosan (HG, hydrolyzed glucan) on the structure and metabolism of fecal microbiota in Chinese healthy people was investigated by an in vitro simulated intestinal microecology fermentation model.
Xionge Pi+4 more
doaj +1 more source
Characterization of Zymosan-Modulated Neutrophils With Neuroregenerative Properties
Recent studies using advanced techniques such as single cell RNA sequencing (scRNAseq), high parameter flow cytometry, and proteomics reveal that neutrophils are more heterogeneous than previously appreciated. Unique subsets have been identified in the context of bacterial and parasitic infections, cancer, and tissue injury and repair.
Andrew D. Jerome+11 more
openaire +3 more sources
Phagosome-lysosome fusion is a calcium-independent event in macrophages. [PDF]
Phagosome-lysosome membrane fusion is a highly regulated event that is essential for intracellular killing of microorganisms. Functionally, it represents a form of polarized regulated secretion, which is classically dependent on increases in ...
Ernst, JD+5 more
core +2 more sources