Results 41 to 50 of about 32,279 (227)

Zymosan-mediated inflammation impairs in vivo reverse cholesterol transport[S]

Journal of Lipid Research, 2011
Inflammation has been proposed to impair HDL function and reverse cholesterol transport (RCT). We investigated the effects of inflammation mediated by zymosan, a yeast glucan, on multiple steps along the RCT pathway in vivo and ex vivo.
Priya Malik, Stela Z. Berisha, Jennifer Santore, Colin Agatisa-Boyle, Gregory Brubaker, Jonathan D. Smith   +5 more
doaj   +1 more source

Zymosan-a Protects the Hematopoietic System from Radiation-Induced Damage by Targeting TLR2 Signaling Pathway

Cellular Physiology and Biochemistry, 2017
Background/Aims: The hematopoietic system is vulnerable to ionizing radiation and is often severely damaged by radiation. Molecules affecting radioresistance include Toll-like receptor 2.
Jicong Du, Ying Cheng, Suhe Dong, Pei Zhang, Jiaming Guo, Jiaqi Han, Fu Gao, Hainan Zhao, Ding Sun, Jianguo Cui, Jianming Cai, Cong Liu   +11 more
doaj   +1 more source

Zymosan A Improved Doxorubicin‐Induced Ventricular Remodeling by Evoking Heightened Cardiac Inflammatory Responses and Healing in Mice

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background Doxorubicin‐induced myocardial injury is reflected by the presence of vacuolization in both clinical and animal models. The lack of scar tissue to replace the vacuolizated cardiomyocytes indicates that insufficient cardiac inflammation and ...
Guiwen Xu, Zhujing Hao, Wei Xiao, Ruopeng Tan, Mengyang Yuan, Yunlong Xia, Yang Liu   +6 more
doaj   +1 more source

Granulocyte-activating mediators (GRAM) [PDF]

, 1988
In the present study we investigated the capability of human epidermal cells to generate granulocyte-activating mediators (GRAM). It could be shown that human epidermal cells as well as an epidermoid carcinoma cell line (A431) produce an epidermal cell ...
Kapp, A., Möller, A., Putz, Reinhard, Zeck-Kapp, G.   +3 more
core   +1 more source

The influence of reticuloendothelial stimulation on the response of rats to dietary cholesterol*

Journal of Lipid Research, 1962
The influence of zymosan, and of various chemical fractions obtained from the yeast cell wall, on lipid alterations induced by the feeding of a cholesterol-cholate diet to rats was studied.
S.J. Riggi, N.R. Di Luzio
doaj   +1 more source

The Distribution of Complement Proteins in Soft and Hard Coronas Impacts Macrophage Uptake of Nanoparticles

Advanced Healthcare Materials, EarlyView.
Protein corona plays a critical role in the biological behavior of nanoparticles. This study investigates the distribution of complement proteins in soft corona and their impact on the macrophage uptake of polymer nanoparticles. It underlines the significance of soft corona investigation for understanding in vivo performance of nanomedicines.
Ying Qiu, Tianchang He, Chunjie Miao, Xinyang Shi, Yuanyuan Niu, Volker Mailänder, Daniel Crespy, Katharina Landfester, Shuai Jiang   +8 more
wiley   +1 more source

Study on the Therapeutic Effects and Mechanisms of Gintonin in Irritable Bowel Syndrome and Its Relationship with TRPV1, TRPV4, and NaV1.5

Pharmaceuticals
Irritable bowel syndrome (IBS) is a gastrointestinal (GI) disease accompanied by changes in bowel habits without any specific cause. Gintonin is a newly isolated glycoprotein from ginseng that is a lysophosphatidic acid (LPA) receptor ligand.
Na-Ri Choi, Seok-Jae Ko, Joo-Hyun Nam, Woo-Gyun Choi, Jong-Hwan Lee, Seung-Yeol Nah, Jae-Woo Park, Byung-Joo Kim   +7 more
doaj   +1 more source

Effects of pH on the Adsorption and Desorption of Naringin onto Zymosan A in Aqueous Systems [PDF]

Chemical and Biochemical Engineering Quarterly
This study aimed to investigate the interactions between naringin and dietary fiber from yeast (zymosan A) through adsorption and desorption processes. The effects of different solution pH conditions (pH 3.0, pH 7.0, and pure water at pH 5.5), as well as
P. Matić, P. Pőc, L. Šoher, D. Kenjerić, L. Jakobek   +4 more
doaj   +1 more source

Inflammation and resolution are associated with upregulation of fatty acid β-oxidation in Zymosan-induced peritonitis. [PDF]

PLoS ONE, 2013
Inflammation is a fundamental defensive response to harmful stimuli. However, it can cause damage if it does not subside. To avoid such damage, organisms have developed a mechanism called resolution of inflammation.
Yusuke Fujieda, Atsushi Manno, Yasuhiro Hayashi, Nelson Rhodes, Lining Guo, Makoto Arita, Takeshi Bamba, Eiichiro Fukusaki   +7 more
doaj   +1 more source

Decoding the Pathophysiology of Autoimmune Diseases—Mechanism, Triggers, and Nanotherapeutics: A Review

Advanced NanoBiomed Research, EarlyView.
This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari, Yunhui Min, Eun‐Ju Ko, Doyoung Kwon, Rehan Khan, Young‐Ok Son   +5 more
wiley   +1 more source