Optimisation of phagocytosis assay in rainbow trout (Oncorhynchus mykiss)
Veterinární Medicína, 2021 A phagocytosis assay is one of the most commonly used functional immunological methods. There are many possible ways of assessing leucocytes and their ability to ingest different particles.
H Minarova +6 more
doaj +1 more source
Comparative lipid profiling dataset of the inflammation-induced optic nerve regeneration. [PDF]
, 2019 In adult mammals, retinal ganglion cells (RGCs) fail to regenerate following damage. As a result, RGCs die after acute injury and in progressive degenerative diseases such as glaucoma; this can lead to permanent vision loss and, eventually, blindness ...
Bhattacharya, Sanjoy K +5 more
core +1 more source
Cell Death and Disease, 2016 Programmed cell death-1 (PD-1) is a member of the CD28 superfamily that delivers negative signals on interaction with its 2 ligands, PD-L1 and PD-L2.
Wenna Chen +4 more
semanticscholar +1 more source
Modulation of apoprotein E secretion in response to receptor-mediated endocytosis in resident and inflammatory macrophages. [PDF]
, 1984 We have determined the effect of various endocytic ligands on the secretion of ApoE by macrophages. ApoE was a major secreted protein of resident macrophages, but BCG-activated macrophages secreted little ApoE and periodate-elicited macrophages secreted ...
Takemura, R, Werb, Z
core +2 more sources
Consequences of altered eicosanoid patterns for nociceptive processing in mPGES-1-deficient mice [PDF]
, 2007 Cyclooxygenase-2 (COX-2)-dependent prostaglandin (PG) E2 synthesis in the spinal cord plays a major role in the development of inflammatory hyperalgesia and allodynia. Microsomal PGE2 synthase-1 (mPGES-1) isomerizes COX-2-derived PGH2 to PGE2.
Angioni, Carlo Federico +8 more
core +1 more source
Immunomodulatory properties of recombinant human granulocyte-macrophage colony-stimulating factor
Медицинская иммунология, 2023 Granulocyte-macrophage colony stimulating factor (GM-CSF) is a myelopoietic growth factor that exerts pleiotropic effect not only on the differentiation of immature progenitor cells into polymorphonuclear neutrophils, monocytes/macrophages and dendritic ...
G. M. Sysoeva +3 more
doaj +1 more source
Dendritic cells activated with products released by schistosome larvae drive Th2-type immune responses, which can be inhibited by manipulation of CD40 costimulation [PDF]
, 2005 The early immune events in response to infective larvae of the parasitic helminth Schistosoma mansoni are poorly understood, but here for the first time we report on the potential of products released by schistosome larvae (material released in the first
Jenkins, S J, Mountford, A P
core +2 more sources
Complement activation and protein adsorption by carbon nanotubes [PDF]
, 2006 As a first step to validate the use of carbon nanotubes as novel vaccine or drug delivery devices, their interaction with a part of the human immune system, complement, has been explored.
Flahaut, Emmanuel +5 more
core +2 more sources
Prostaglandins mediate zymosan-induced sickness behavior in mice
Journal of Physiological Sciences, 2017 Previous studies have demonstrated that zymosan, a cell wall component of the yeast Saccharomyces cerevisiae, induces inflammation in experimental models. However, few studies have evaluated the potential of zymosan to induce sickness behavior, a central
J. Lima +3 more
semanticscholar +1 more source
Fungal Zymosan and Mannan Activate the Cryopyrin Inflammasome [PDF]
Journal of Biological Chemistry, 2009 Some fungal species are opportunistic pathogens that can cause infection in people with compromised immune systems. Activation of caspase-1 and the subsequent secretion of mature interleukin (IL)-1beta is a major signaling pathway of the innate immune system, but how yeasts induce caspase-1 activation is unknown.
R. K. Subbarao Malireddi +2 more
openaire +3 more sources